Clinical characteristics and treatment outcomes of angioid streak associated choroidal neovascular membrane (AS-CNV): a Zambian case series

Abstract Background Aggressive surgical therapy such as en-bloc resection of the joint is favored in the treatment of sternoclavicular (SC) septic arthritis. However, this practice is based on expert opinion and small case series. We analyzed the clinical characteristics and treatment outcomes of patients with S. aureus SC septic arthritis treated with medical therapy alone or with limited surgical therapy. Methods All adult patients with SC septic arthritis caused by S. aureus at the Asan Medical Center between September 2009 and December 2016 were retrospectively reviewed. Demographic characteristics, laboratory results, underlying diseases/conditions, patient management, and treatment outcomes were assessed. SC septic arthritis due to S. aureus was defined if patients had positive cultures of specimens from the SC joint, or if blood cultures yielded S. aureus, together with physical findings and imaging studies supporting the diagnosis of SC septic arthritis. Limited surgical therapy was defined as simple incision, drainage, and debridement of infected SC joint. Results In total, 22 cases of S. aureus SC septic arthritis were enrolled. Of these 22 patients, 11 received medical therapy alone, 11 underwent limited surgical therapy, and none underwent aggressive surgery. Most patients (73%) had underlying predisposing conditions such as infection at a distant site, diabetes, and liver cirrhosis, and none had IV drug abuse or HIV infection. Complications such as chest wall and/or neck abscess, clavicular and/or sternal osteomyelitis were identified in 18 patients (82%). Patients with chest wall and/or neck abscess had a tendency to be treated with limited surgery than patients without them (73% vs. 27%, P = 0.09). The median duration of intravenous antibiotics in all patients was 35 days (IQR 25–46 days). After a median follow-up of 31 months (IQR 2–40 months), there was no relapse of SC septic arthritis or deterioration of joint function. Conclusion Medical therapy alone or with limited surgical therapy appears to be a successful therapeutic strategy for the complicated S. aureus SC septic arthritis in a selected patient. Disclosures All authors: No reported disclosures.

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Retrospective Study on Clinical Features and Treatment Outcomes of Nontraumatic Inguinal Hernias in 41 Dogs

Journal of the American Animal Hospital Association ◽

10.5326/jaaha-ms-7106 ◽

2020 ◽

Vol 56 (6) ◽

pp. 301

Author(s):

Teruo Itoh ◽

Atsuko Kojimoto ◽

Kentaro Kojima ◽

Hiroki Shii

Keyword(s):

Small Intestine ◽

Treatment Outcomes ◽

Medical Records ◽

Clinical Characteristics ◽

Case Series ◽

Long Term Results ◽

Inguinal Hernias ◽

Small Intestines ◽

Resection And Anastomosis

ABSTRACT Several factors are suggested to be involved in the development of nontraumatic inguinal hernias (NTIHs) in dogs, but case series studies focusing on the etiology and treatment outcomes are limited. The aim of this study was to retrospectively evaluate the clinical characteristics and treatment outcomes of NTIHs in dogs. Medical records of 42 dogs with surgically treated NTIHs were reviewed. Forty-one dogs were included in the study, all dogs were small breeds weighing <10 kg, and middle to older age (>5 yr old; 33 cases), female sex (34 cases), and miniature dachshunds (26 cases) predominated. Left-sided occurrence was common (30 left, 9 right, 2 bilateral), and organ protrusion was seen in 22 cases (15 uteri, 9 small intestines, 1 colon). Fourteen of 15 uterine herniations (93%) were located left side. Ovariohysterectomy was performed with herniorrhaphy in 27/30 intact bitches, two of whom also underwent resection and anastomosis of a devitalized portion of the small intestine. Recurrence was seen in only one male dog. These results suggest that NTIHs are more likely to occur in small-breed female dogs, and that age may increase the risk of left-sided uterine protrusion; however, the long-term results after herniorrhaphy with ovariohysterectomy are excellent.

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Clinical characteristics and treatment outcomes in acromegaly, a retrospective single-center case series from Thailand

Pan African Medical Journal ◽

10.11604/pamj.2021.40.31.29920 ◽

2021 ◽

Vol 40 ◽

Author(s):

Poranee Ganokroj ◽

Sarat Sunthornyothin ◽

Rungsak Siwanuwatn ◽

Kraisri Chantra ◽

Patinut Buranasupkajorn ◽

...

Keyword(s):

Treatment Outcomes ◽

Clinical Characteristics ◽

Case Series ◽

Single Center

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Treatment Outcomes of Lesser Tuberosity Osteotomy Nonunion After Total Shoulder Arthroplasty

Journal of Shoulder and Elbow Arthroplasty ◽

10.1177/2471549218807777 ◽

2018 ◽

Vol 2 ◽

pp. 247154921880777

Author(s):

Zachary J Bloom ◽

Cesar D Lopez, BA ◽

Stephen P Maier ◽

Brian B Shiu ◽

Djuro Petkovic ◽

...

Keyword(s):

Treatment Outcomes ◽

Shoulder Arthroplasty ◽

Surgical Repair ◽

Total Shoulder Arthroplasty ◽

Case Series ◽

Radiographic Evaluation ◽

Lesser Tuberosity ◽

Conservative Care ◽

Conservative Group

Introduction Lesser tuberosity osteotomy (LTO) during anatomic total shoulder arthroplasty has a 13% nonunion rate. Treatment for LTO nonunion is controversial and poorly described in the literature. The purpose of this study was to compare the surgical and nonsurgical treatment outcomes of LTO nonunion. Methods A retrospective case series of 9 consecutive patients with LTO nonunion after primary anatomic shoulder arthroplasty at 1 institution from 2010 to 2016 were studied. Outcomes measured were radiographic evaluation of LTO on axillary X-ray, clinical range of motion (ROM), subscapularis strength, and pain at the time of LTO nonunion diagnosis and after either conservative care or surgical repair of the LTO nonunion. Results LTO nonunion was treated surgically in 4 and conservatively in 5 patients with average follow-up of 30 and 22 months, respectively. There were no significant differences in age, sex, or smoking status between groups. Treatment decision was a shared model of surgeon and patient. Displaced LTO nonunion was treated surgically in 2 and conservatively in 3 patients. There were no differences in LTO union rate of 50% in the surgical versus 60% in the conservative group. Abdominal compression test was abnormal in 50% of surgical versus 40% of conservative groups. At follow-up, ROM was lower in the surgical group with 128° forward elevation (FE) and 33° external rotation (ER) compared to 148° FE and 62° ER. Only 1 patient with LTO nonunion required conversion to reverse replacement. Conclusion LTO nonunion after shoulder arthroplasty is rare. Surgical repair of LTO nonunion does not significantly improve clinical or radiographic outcomes compared to conservative care.

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Etiologies and clinical characteristics of young patients with angle-closure glaucoma: a 15-year single-center retrospective study

Graefe s Archive for Clinical and Experimental Ophthalmology ◽

10.1007/s00417-021-05172-6 ◽

2021 ◽

Author(s):

Feng Gao ◽

Jiajian Wang ◽

Junyi Chen ◽

Xiaolei Wang ◽

Yuhong Chen ◽

...

Keyword(s):

Clinical Characteristics ◽

Anterior Segment ◽

Young Patients ◽

Case Series ◽

Neovascular Glaucoma ◽

Angle Closure Glaucoma ◽

Angle Closure ◽

Primary Angle Closure Glaucoma ◽

Uncommon Presentation ◽

Underlying Causes

Abstract Purpose To investigate the etiologies and the clinical characteristics of angle-closure glaucoma (ACG) patients younger than 40 years old in Chinese. Methods Inpatients with diagnosis of ACG and diagnosed age younger than or equal to 40 years old, who were admitted in Eye, Ear, Nose, and Throat Hospital Fudan University from 2002 to 2017, were included in this retrospective non-comparative case series. The underlying causes and clinical features for all the patients were analyzed by comprehensive review of medical charts. Results A total of 298 patients (463 eyes) met the criteria, including 153 females (51.3%) and 145 males (48.7%); the mean age was 25.6 ± 13.0 years. Primary angle-closure glaucoma (PACG), uveitis, and anterior segment dysgenesis (ASD) were the top three etiologies in our patients, which accounted for 32.6%, 20.3%, and 15.1% of the total patients respectively. PACG mainly occurs after 30 years of age and ASD is the top reason of ACG in patients younger than 20 years old. Other known etiologies include iridocorneal endothelial syndrome, neovascular glaucoma, nanophthalmos, retinitis pigmentosa, spherophakia, bestrophinopathy, persistent fetal vasculature, iridociliary cysts, congenital retinoschisis, Marfan’s syndrome, retinopathy of prematurity, familial exudative vitreoretinopathy, congenital retinal folds, Coat’s disease, and neurofibromatosis. Conclusions We described the uncommon presentation of ACG in Chinese young patients. Although unusual, most of the etiologies could be identified. Therefore, more careful and comprehensive examinations are needed for early detection and timely treatment for young ACG patients.

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