Arthrocentesis of the Temporomandibular Joint: Systematic Review and Clinical Implications of Research Findings

2021 ◽  
Vol 35 (1) ◽  
pp. 17-29
Author(s):  
Luca Guarda-Nardini ◽  
Andrè De Almeida ◽  
Daniele Manfredini
Cancers ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1334
Author(s):  
Ye Liu ◽  
Zahra Mohri ◽  
Wissal Alsheikh ◽  
Umber Cheema

The development of biomimetic, human tissue models is recognized as being an important step for transitioning in vitro research findings to the native in vivo response. Oftentimes, 2D models lack the necessary complexity to truly recapitulate cellular responses. The introduction of physiological features into 3D models informs us of how each component feature alters specific cellular response. We conducted a systematic review of research papers where the focus was the introduction of key biomimetic features into in vitro models of cancer, including 3D culture and hypoxia. We analysed outcomes from these and compiled our findings into distinct groupings to ascertain which biomimetic parameters correlated with specific responses. We found a number of biomimetic features which primed cancer cells to respond in a manner which matched in vivo response.


2014 ◽  
Vol 38 (6) ◽  
pp. 260-264 ◽  
Author(s):  
Alan Meaden ◽  
Martin Commander ◽  
Colin Cowan ◽  
Tom Edwards

Aims and methodTo build on previous research findings by examining engagement and problematic behaviours of patients in 10 residential rehabilitation units. Two measures were completed on patients in community rehabilitation, longer-term complex care and high-dependency units (109 patients in total). Data were analysed and categorised into higher-engagement ratings across the domains of engagement and behaviour over the past 6 months and lifetime in terms of presence of the behaviour and likelihood of resulting harm.ResultsData were available for 73% of patients. All aspects of engagement were consistently low for all units, with highest levels in community rehabilitation units. Levels of problematic behaviours were similar across all units. Socially inappropriate behaviours and failure to complete everyday activities were evident for over half of all patients and higher for lifetime prevalence. Verbal aggression was at significantly lower levels in community units. Lifetime behaviours likely to lead to harm were much more evident in high-dependency units.Clinical implicationsDespite some benefits of this type of care, patients continue to present challenges in engagement and problematic behaviours that require new approaches and a change in focus.


2015 ◽  
Vol 60 (1) ◽  
pp. e15-e49 ◽  
Author(s):  
I. Pluvy ◽  
M. Panouillères ◽  
I. Garrido ◽  
J. Pauchot ◽  
J. Saboye ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document