Cocaine Use during Pregnancy Research Findings and Clinical Implications

1990 ◽  
Vol 19 (4) ◽  
pp. 285-292 ◽  
Author(s):  
Martha Lynch ◽  
Valerie Ann Mckeon
Keyword(s):  
Clinical Implications ◽  
Cocaine Use ◽  
Research Findings

scholarly journals Patient engagement and problematic behaviours in nurse-staffed residential rehabilitation units

2014 ◽  
Vol 38 (6) ◽  
pp. 260-264 ◽  
Author(s):  
Alan Meaden ◽  
Martin Commander ◽  
Colin Cowan ◽  
Tom Edwards
Keyword(s):  
Clinical Implications ◽  
Complex Care ◽  
The Past ◽  
Everyday Activities ◽  
Community Rehabilitation ◽  
High Dependency ◽  
Total Data ◽  
Research Findings ◽  
Two Measures ◽  
Residential Rehabilitation

Aims and methodTo build on previous research findings by examining engagement and problematic behaviours of patients in 10 residential rehabilitation units. Two measures were completed on patients in community rehabilitation, longer-term complex care and high-dependency units (109 patients in total). Data were analysed and categorised into higher-engagement ratings across the domains of engagement and behaviour over the past 6 months and lifetime in terms of presence of the behaviour and likelihood of resulting harm.ResultsData were available for 73% of patients. All aspects of engagement were consistently low for all units, with highest levels in community rehabilitation units. Levels of problematic behaviours were similar across all units. Socially inappropriate behaviours and failure to complete everyday activities were evident for over half of all patients and higher for lifetime prevalence. Verbal aggression was at significantly lower levels in community units. Lifetime behaviours likely to lead to harm were much more evident in high-dependency units.Clinical implicationsDespite some benefits of this type of care, patients continue to present challenges in engagement and problematic behaviours that require new approaches and a change in focus.

Family Caregiving: Research Findings and Clinical Implications

1998 ◽  
pp. 499-523 ◽  
Author(s):  
Steven H. Zarit ◽  
Adam Davey ◽  
Anne B. Edwards ◽  
Elia E. Femia ◽  
Shannon E. Jarrott
Keyword(s):  
Family Caregiving ◽  
Clinical Implications ◽  
Research Findings

The Cochlear Nucleus as a Generator of Tinnitus-Related Signals

2018 ◽  
pp. 188-222
Author(s):  
J.A. Kaltenbach ◽  
D.A. Godfrey
Keyword(s):  
Cochlear Nucleus ◽  
Neural Circuitry ◽  
Clinical Implications ◽  
Future Treatment ◽  
Cortical Level ◽  
The Future ◽  
Research Findings ◽  
The Brain

Tinnitus most commonly begins with alterations of input from the ear resulting from cochlear trauma or overstimulation of the ear. Because the cochlear nucleus is the first processing center in the brain receiving cochlear input, it is the first brainstem station to adjust to this modified input from the cochlea. Research published over the last 30 years demonstrates changes in neural circuitry and activity in the cochlear nucleus that are associated with and may be the origin of the signals that give rise to tinnitus percepts at the cortical level. This chapter summarizes what is known about these disturbances and their relationships to tinnitus. It also summarizes the mechanisms that trigger tinnitus-related disturbances and the anatomical, chemical, neurophysiological, and biophysical defects that underlie them. It concludes by highlighting some major controversies that research findings have generated and discussing the clinical implications the findings have for the future treatment of tinnitus.

scholarly journals Potential Clinical Implications of miR-1 and miR-21 in Heart Disease and Cardioprotection

2020 ◽  
Vol 21 (3) ◽  
pp. 700 ◽  
Author(s):  
Branislav Kura ◽  
Barbora Kalocayova ◽  
Yvan Devaux ◽  
Monika Bartekova
Keyword(s):  
Public Health ◽  
Current Knowledge ◽  
Cardiac Injury ◽  
Review Article ◽  
Public Health Issue ◽  
Modern World ◽  
Clinical Implications ◽  
Research Findings ◽  
Non Coding Rnas ◽  
New Generation

The interest in non-coding RNAs, which started more than a decade ago, has still not weakened. A wealth of experimental and clinical studies has suggested the potential of non-coding RNAs, especially the short-sized microRNAs (miRs), to be used as the new generation of therapeutic targets and biomarkers of cardiovascular disease, an ever-growing public health issue in the modern world. Among the hundreds of miRs characterized so far, microRNA-1 (miR-1) and microRNA-21 (miR-21) have received some attention and have been associated with cardiac injury and cardioprotection. In this review article, we summarize the current knowledge of the function of these two miRs in the heart, their association with cardiac injury, and their potential cardioprotective roles and biomarker value. While this field has already been extensively studied, much remains to be done before research findings can be translated into clinical application for patient’s benefit.

Melody, Memory, and Engagement in Alzheimer’s Disease

2019 ◽  
pp. 67-87
Author(s):  
Ashley D. Vanstone ◽  
Lola L. Cuddy
Keyword(s):  
Individual Differences ◽  
Process Model ◽  
Clinical Case ◽  
Theory Building ◽  
Clinical Implications ◽  
Case Formulation ◽  
Research Findings ◽  
Inclusive Concept ◽  
Clinical Case Formulation ◽  
Case Based

What are the personal and clinical implications of preserved memory for music in dementia? In light of this question, a framework is proposed for integrating basic and clinical research findings and for case formulation and theory building in music-based interventions. Elaborating on the Comprehensive Process Model of Engagement, a proposal is made for music engagement as an inclusive concept that encompasses the variety of ways in which individuals involve themselves with musical stimuli. It is argued that instances of music engagement arise through the combined influence of person, stimulus, and environment attributes. Preserved memory for melodies is discussed as an attribute of the person with particular relevance to music engagement. This approach orients naturally toward considering individual differences and, as such, lends itself well to case-based research and clinical case formulation.

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