scholarly journals Enzymatically Degraded, Nonoxidized LDL Induces Human Vascular Smooth Muscle Cell Activation, Foam Cell Transformation, and Proliferation

Circulation ◽  
2000 ◽  
Vol 101 (15) ◽  
pp. 1799-1805 ◽  
Author(s):  
Mariam Klouche ◽  
Stefan Rose-John ◽  
Walther Schmiedt ◽  
Sucharit Bhakdi
Keyword(s):  
Smooth Muscle ◽  
Vascular Smooth Muscle ◽  
Smooth Muscle Cell ◽  
Muscle Cell ◽  
Vascular Smooth Muscle Cell ◽  
Cell Activation ◽  
Cell Transformation ◽  
Foam Cell

scholarly journals Nitric Oxide Attenuates Vascular Smooth Muscle Cell Activation by Interferon-

1996 ◽  
Vol 271 (19) ◽  
pp. 11317-11324 ◽  
Author(s):  
Wee Soo Shin ◽  
Yi-Hui Hong ◽  
Hai-Bing Peng ◽  
Raffaele De Caterina ◽  
Peter Libby ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Smooth Muscle ◽  
Vascular Smooth Muscle ◽  
Smooth Muscle Cell ◽  
Muscle Cell ◽  
Vascular Smooth Muscle Cell ◽  
Cell Activation

scholarly journals A proteomic approach to the investigation of early events involved in vascular smooth muscle cell activation

2007 ◽  
Vol 328 (1) ◽  
pp. 185-195 ◽  
Author(s):  
Claudia Boccardi ◽  
Antonella Cecchettini ◽  
Anna Caselli ◽  
Guido Camici ◽  
Monica Evangelista ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Vascular Smooth Muscle ◽  
Smooth Muscle Cell ◽  
Muscle Cell ◽  
Vascular Smooth Muscle Cell ◽  
Cell Activation ◽  
Proteomic Approach

scholarly journals Associations between Vaspin Levels and Coronary Artery Disease

2020 ◽  
Vol 4 (3) ◽  
pp. 211-216
Author(s):  
Lutfu Askin ◽  
Okan Tanriverdi ◽  
Hakan Tibilli ◽  
Serdar Turkmen
Keyword(s):  
Coronary Artery Disease ◽  
Smooth Muscle ◽  
Coronary Artery ◽  
Vascular Smooth Muscle ◽  
Smooth Muscle Cell ◽  
Muscle Cell ◽  
Vascular Smooth Muscle Cell ◽  
Foam Cell ◽  
Foam Cell Formation ◽  
Artery Disease

The relationship between serum vaspin levels and metabolic or coronary artery disease is currently of interest for researchers. Although adipokine concentrations have been shown to be increased significantly in atherosclerotic lesions, the role adipokines in the atherosclerotic process remains to be elucidated. Vaspin is a new biological marker associated with obesity and impaired insulin sensitivity. Plasma vaspin concentration has been shown to correlate with the severity of coronary artery disease. Vascular inflammation triggered by vaspin inhibits atherogenesis by suppressing macrophage foam cell formation and vascular smooth muscle cell migration and proliferation. Vaspin also contributes to plaque stabilization by increasing collagen content and reducing the intraplaque macrophage to vascular smooth muscle cell ratio. The therapeutic goal concerning vaspin is to fight atherosclerosis and related diseases, as well as to maintain vascular health.

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