Abstract 1776: Peripheral Arterial Disease Determined by Screening Ankle Brachial Index Testing Predicts High Risk Findings On Stress Myocardial Perfusion SPECT Imaging

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
R Parker Ward ◽  
Linda A Taillon ◽  
Justin Weiner ◽  
Kim A Williams
Keyword(s):  
Coronary Artery Disease ◽  
Stress Testing ◽  
Independent Predictor ◽  
Ankle Brachial Index ◽  
Myocardial Perfusion Spect ◽  
Arterial Disease ◽  
Stress Myocardial Perfusion ◽  
Perfusion Spect ◽  
Artery Disease ◽  
Peripheral Arterial

Background: Peripheral arterial disease (PAD) as determined by ankle brachial index (ABI) testing is a potent marker of adverse cardiovascular prognosis. Stress myocardial perfusion SPECT (MPS) testing allows diagnosis of coronary artery disease (CAD) and stratification of cardiovascular risk. The stress MPS findings in patients (pts) with occult PAD are unknown. Accordingly, our goal was to determine the prevalence high risk (HR) MPS findings in pts with occult PAD diagnosed by screening ABI who are referred for MPS testing. Methods: As part of a prospective data collection, 679 male pts referred for MPS were screened for PAD with ABI evaluation. Pts with non-diagnostic ABIs (>1.3) or prior known PAD were excluded. PAD was defined as an ABI ≤ 0.9. PAD severity (mild [ABI 0.8 – 0.9], moderate [ABI 0.4 – 0.8], severe [<0.4]) and symptoms of PAD were also noted. CAD was defined as mild (summed stress score (SSS) ≥ 4) or severe (SSS>8), and the composite of any HR finding (SSS>8, left ventricular ejection fraction [LVEF] < 40%, or TID) was recorded. Results: PAD was present in 28%. Of pts found to have PAD, 65% reported no lower extremity symptoms. Compared to no PAD, pts with PAD were found to have significantly more mild or greater CAD (51% vs. 36%, p<0.01), severe CAD (35% vs. 19%, p<0.01), LV dysfunction [LVEF < 40%] (14% vs 7%, p < 0.01), and composite HR MPS findings (40% vs. 22%, p<0.01). On multivariate logistic regression analysis considering age, HTN, diabetes, tobacco use, hypercholesterolemia, and prior coronary artery disease, PAD was found to be an independent predictor of mild or greater CAD (OR 1.6, 95% CI 1.1–2.4, p<0.01), severe CAD (OR 1.9 95% CI 1.3–3.0, p<0.01), and any HR MPS finding (OR 2.0 95% CI 1.3–3.0, p<0.01). Conclusions: Among men referred for stress testing, occult PAD is common, and is an independent predictor of significant CAD and HR findings on MPS testing. Further study is needed to determine if PAD in pts without an indication for stress testing may benefit from screening MPS.

scholarly journals To Study the Sensitivity and Specificity of Ankle Brachial Index in Diagnosis of Peripheral Arterial Disease in Diabetics With Coronary Artery Disease at a Large Tertiary Care Teaching Hospital

2020 ◽  
pp. 29-33
Author(s):  
Dr. Sajad Hussain Bhat ◽  
Dr. Adil Majeed ◽  
Dr. Mohd Yousuf Dar ◽  
Mohd Yousuf Dar
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Peripheral Arterial Disease ◽  
Sensitivity And Specificity ◽  
Teaching Hospital ◽  
Ankle Brachial Index ◽  
Arterial Disease ◽  
Diabetic Patients ◽  
Artery Disease ◽  
Peripheral Arterial

The aim of study was to determine the sensitivity and specificity of ankle brachial index in diagnosis of peripheral arterial disease in diabetics with coronary artery disease at a teaching hospital in North India. Materials and methods: All diabetic patients admitted with coronary artery disease who undergo coronary angiography irrespective of their presentation (stable angina, unstable angina, NSTEMI, STEMI) were included in the study. Systolic blood pressures of both arms at the brachial arteries and both lower limbs at the dorsalis pedis arteries were taken with the help of sphygmomanometer and a hand held doppler probe and recorded in the proforma. The higher of the two systolic pressures recorded at the ankle was divided by the highest of the systolic pressures recorded in the arms to get the ankle brachial index. The results of ABI were compared with peripheral angiography.

scholarly journals Ankle-Brachial Index predicts Coronary Artery Disease associated with Peripheral Arterial Disease

1970 ◽  
Vol 6 (1) ◽  
pp. 23-25
Author(s):  
SM Ahsan Habib ◽  
M Nazrul Islam ◽  
Kamal Pasha ◽  
Saleh Ahmed Nurul Alam ◽  
Khaled Mohsin ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Peripheral Arterial Disease ◽  
Ankle Brachial Index ◽  
Arterial Disease ◽  
Left Main ◽  
Group I ◽  
Group Ii ◽  
Artery Disease ◽  
Peripheral Arterial

Most common cause of Peripheral Arterial Disease (PAD) is atherosclerosis. Atherosclerosis is a generalized disease, also involving coronary and carotid arteries. Often atherosclerotic coronary artery disease (CAD) is associated with PAD. This prospective observational study was conducted in the National Institute of Cardiovascular Diseases, Dhaka, Bangladesh, during July 2004 to June 2005. Total 58 patients with PAD were included in the study. Patients were classified as group I having normal coronary artery, group II insignificant CAD (Left main <50% stenosis, others <70% stenosis) and group III, significant CAD (Left main ≥50% stenosis, others ≥70% stenosis). Ankle-brachial index was significantly low (0.75±0.25 Vs 0.37±0.40) in the patients with coronary artery disease (Group II and III) compare to non-CAD (P =0.001).This study suggests that ankle-brachial index (ABI) have significant relation with the presence of CAD. Key words: Ankle-Brachial Index; peripheral arterial disease DOI: 10.3329/uhj.v6i1.7186University Heart Journal Vol.6(1) 2010 pp.23-25

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