Abstract 18096: Screening of Abdominal Aortic Aneurysm during Transthoracic Echocardiography

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Takao Kato ◽  
Masahiro Kimura ◽  
Moritoshi Funasako ◽  
Eisaku Nakane ◽  
Toshiaki Izumi ◽  
...  

Introduction: We previously reported that the prevalence of abdominal aortic aneurysm (AAA) in patients who underwent scheduled transthoracic echocardiography (TTE) was higher than that of AAA in patients who underwent abdominal ultrasonography (AUS). However, the patient backgrounds differed significantly between the two groups. Hypothesis: We hypothesized TTE detected AAA as similarly as AUS, one of standard methods for the screening of AAA. Methods: A total of 7,619 patients who were scheduled for TTE from 2009 to 2010 in our hospital were prospectively included. The abdominal aorta was evaluated at the end of the routine protocol. All patients who received scheduled abdominal ultrasonography (AUS) during the same period, a total of 15,433 patients, were included. The patients with known AAA and those without consent were excluded. In order to compare the TTE group to AUS group, we developed a propensity score for profiles of patients who received TTE or AUS for potential confounding bias. Specifically, a multivariate logistic regression model was fit with TTE or AUS as a dependent variable, which included age, sex, numbers of comorbidities, and the presence of each comorbidity. Consequently, 4,388 patients in each group were matched for analyses. Results: In propensity-matched patients, AAA was detected in 59 patients of TTE group and 48 patients of AUS group and the prevalence of the detection of AAA was not different between TTE and AUS (p=0.331). Positive associations were observed between AAA detected and male sex (adjusted odds ratio [OR], 3.25; 95% CI, 2.05-5.15; P<.001), older age (adjusted OR, 1.029; 95% CI, 1.01-1.046; P<.001), having ischemic heart disease (adjusted OR, 1.78; 95% CI, 1.04-3.03; P=0.033), and having hypertension (adjusted OR, 2.16; 95% CI, 1.38-3.38; P=001). Conclusions: TTE detected AAA as similarly as AUS. This result suggested that additional examination of the abdominal aorta during scheduled TTE was efficient for the screening of AAA.

2019 ◽  
Vol 13 (9) ◽  
pp. 430-434
Author(s):  
Ian Peate

This is the second article in a series of articles regarding screening programmes. In this article, an overview of the abdominal aorta is provided. The article also considers the abdominal aortic aneurysm screening programme. Aortic abdominal aneurysm is described. The majority of abdominal aortic aneurysms are asymptomatic; however, if there are any symptoms, these are explained. All four UK countries offer men aged 65 years and over a screening opportunity using an ultrasound scan, the fundamental aspects of abdominal aortic aneurysm screening programmes is offered. It is emphasised that screening is not mandatory in the UK; the man has a right to decline the invitation to attend any screening programme.


Author(s):  
Florentina Ene ◽  
Carine Gachon ◽  
Patrick Delassus ◽  
Liam Morris

Abdominal aortic aneurysm (AAA) represents an abnormal dilatation and weakening of the abdominal aorta with high risk of rupture. Most aneurysms of the infrarenal aorta possess an asymmetrical fusiform morphology.


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Chie Miyamoto ◽  
Hirona Kugo ◽  
Keisuke Hashimoto ◽  
Tatsuya Moriyama ◽  
Nobuhiro Zaima

AbstractAbdominal aortic aneurysm (AAA) is a vascular disease characterized by weakening of the vascular walls. Male sex is a risk factor for AAA, and peak AAA incidence occurs in men 10 years earlier than in women. However, the growth rate of AAA is faster in women, and women have a higher mortality due to AAA rupture. The mechanisms underlying sex-related differences in AAA remain unknown. Herein, we evaluated the effects of ovariectomy (OVX) on AAA in rats. Upon evaluation of the effects of OVX and AAA induction, AAA incidence rate and the aneurysm diameter increased in the OVX group. However, the histopathology in the developed AAA wall was not different between groups. When the effects of OVX on the vascular wall without AAA induction were evaluated, elastin and collagen levels were significantly decreased. Furthermore, the level of matrix metalloproteinase-9 significantly increased in the OVX group. According to our results, it is speculated that decreased levels of collagen and elastin fibers induced by OVX might be involved in increased incidence rate and diameter of AAA. Weakening of the vascular wall before the onset of AAA might be one reason for the faster rate of AAA growth in women.


2019 ◽  
Vol 69 (6) ◽  
pp. e94-e95
Author(s):  
Vivian C. Gomes ◽  
Madhavan L. Raghavan ◽  
Luiz F. da Silva ◽  
Selene Zyngier ◽  
Gina Silvestre ◽  
...  

2015 ◽  
Vol 62 (6) ◽  
pp. 1607-1614.e2 ◽  
Author(s):  
Zhenjie Liu ◽  
Qiwei Wang ◽  
Jun Ren ◽  
Carmel Rebecca Assa ◽  
Stephanie Morgan ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document