scholarly journals Subcutaneous Injection of Nitroglycerin at the Radial Artery Puncture Site Reduces the Risk of Early Radial Artery Occlusion After Transradial Coronary Catheterization

2018 ◽  
Vol 11 (7) ◽  
Author(s):  
Yequn Chen ◽  
Zhiquan Ke ◽  
Jiaxin Xiao ◽  
Mengyue Lin ◽  
Xiru Huang ◽  
...  
Keyword(s):  
Radial Artery ◽  
Subcutaneous Injection ◽  
Treated Group ◽  
Artery Occlusion ◽  
Control Group ◽  
Placebo Control ◽  
Puncture Site ◽  
Coronary Catheterization ◽  
Placebo Control Group ◽  
Radial Artery Occlusion

Background: Transradial coronary catheterization is widely used as a diagnostic or interventional procedure for coronary disease. However, it can lead to adverse complications, such as radial artery occlusion. We sought to determine whether preprocedural injection of nitroglycerin at the radial artery puncture site reduces radial artery occlusion. Methods and Results: A total of 188 patients undergoing transradial coronary catheterization were randomized in a single-blind fashion to receive subcutaneous injection of 0.5 mL 0.1% nitroglycerin or a placebo at the radial artery puncture site. The participants underwent ultrasound examinations of the radial artery before and at 24 hours after the procedure. Of the 188 patients enrolled, 182 completed the study, as the procedure failed in 2 participants in the nitroglycerin-treated group and 4 in the placebo group. Baseline demographic and clinical characteristics were similar between 2 groups. Comparing the radial artery diameters before and after the operation, there was a statistically significant increase in the nitroglycerin-treated group (2.48±0.45 versus 2.45±0.46 mm; P =0.003) but a decrease in the placebo control group (2.41±0.50 versus 2.46±0.49 mm; P <0.001). Importantly, the incidence of radial arterial occlusion was substantially lower in the nitroglycerin-treated group than in the placebo control group (5.4% versus 14.4%; P =0.04). There was not significant difference in other complications (forearm hematoma and radial artery pseudoaneurysm, respectively), and there was no incidence of cause hypotension or an intolerable headache. Conclusions: Subcutaneous injection of nitroglycerin at the radial artery puncture site dilates the radial artery and reduces the incidence of early radial artery occlusion post-catheterization. Clinical Trial Registration: URL: https://www.chictr.org.cn . Unique identifier: ChiCTR-IPR-15006559.

scholarly journals Incidence and predictors of radial artery occlusion after transradial coronary catheterization

2019 ◽  
Vol 71 (1) ◽  
Author(s):  
Mohamed A. Sadaka ◽  
Waleed Etman ◽  
Walid Ahmed ◽  
Saeed Kandil ◽  
Salah Eltahan
Keyword(s):  
Radial Artery ◽  
Artery Occlusion ◽  
Coronary Catheterization ◽  
Radial Artery Occlusion

scholarly journals A Randomized Trial Comparing Short versus Prolonged Hemostasis with Rescue Recanalization by Ipsilateral Ulnar Artery Compression: Impact on Radial Artery Occlusion—The RESCUE-RAO Trial

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Dmitrii V. Ognerubov ◽  
Alexander Sedaghat ◽  
Sergey I. Provatorov ◽  
Andrey S. Tereshchenko ◽  
Olivier F. Bertrand ◽  
...  
Keyword(s):  
Coronary Angiography ◽  
Randomized Trial ◽  
Hospital Discharge ◽  
Radial Artery ◽  
Ulnar Artery ◽  
Artery Occlusion ◽  
Puncture Site ◽  
Coronary Procedures ◽  
Baseline Characteristics ◽  
Radial Artery Occlusion

Background. Despite the enormous benefits of radial access, this route is associated with a risk of radial artery occlusion (RAO). Objective. We compared the incidence of RAO in patients undergoing transradial coronary angiography and intervention after short versus prolonged hemostasis protocol. Also we assessed the efficacy of rescue 1-hour ipsilateral ulnar artery compression if RAO was observed after hemostasis. Material and Methods. Patients referred for elective transradial coronary procedures were eligible. After 6 F radial sheath removal, patients were randomized to short (3 hours) (n = 495) or prolonged (8 hours) (n = 503) hemostasis and a simple bandage was placed over the puncture site. After hemostasis was completed, oximetry plethysmography was used to assess the patency of the radial artery. Results. One thousand patients were randomized. Baseline characteristics were similar between both groups with average age 61.4 ± 9.4 years (71% male) and PCI performed on half of the patients. The RAO rate immediately after hemostasis was 3.2% in the short hemostasis group and 10.1% in the prolonged group ( p < 0.001 ). Rescue recanalization was successful only in the short group in 56.2% (11/19); at hospital discharge, RAO rates were 1.4% in the short group and 10.1% in the prolonged group ( p < 0.001 ). Conclusion. Shorter hemostasis was associated with significantly less RAO compared to prolonged hemostasis. Rescue radial artery recanalization was effective in > 50%, but only in the short hemostasis group.

scholarly journals Influence of Puncture Site on Radial Artery Occlusion After Transradial Coronary Intervention

2016 ◽  
Vol 129 (8) ◽  
pp. 898-902 ◽  
Author(s):  
Xi-Le Bi ◽  
Xiang-Hua Fu ◽  
Xin-Shun Gu ◽  
Yan-Bo Wang ◽  
Wei Li ◽  
...  
Keyword(s):  
Radial Artery ◽  
Coronary Intervention ◽  
Artery Occlusion ◽  
Puncture Site ◽  
Radial Artery Occlusion

P6524The comparison of radial artery occlusion rate after distal radial artery puncture between hemodialysis and non-hemodialysis patients

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
S Yokota ◽  
K Tobita ◽  
T Hayashi ◽  
Y Mashimo ◽  
H Miyashita ◽  
...  
Keyword(s):  
Radial Artery ◽  
Hemodialysis Patients ◽  
Artery Occlusion ◽  
Dialysis Patients ◽  
Puncture Site ◽  
Single Center Study ◽  
Significant Difference ◽  
Radial Artery Occlusion ◽  
Event Rates ◽  
Distal Radial Artery

Abstract Background In recent years it has been attempted to use a distal radial artery (DRA) as a puncture site for cardiac catheterization and intervention. A patency of radial artery is important in hemodialysis patients because the radial artery is source as an arteriovenous shunt. However, the incidence of radial artery occlusion (RAO) is not known after DRA puncture. Purpose To compare RAO rates after DRA puncture between dialysis and non-dialysis patients. Method This was retrospective, observational and single center study. All consecutive 1,533 patients undergoing DRA puncture were analyzed. The primary endpoint is RAO rates. The secondary endpoint is composite bleeding adverse event rates. These endpoints were evaluated by a vascular echocardiography several hours or the next day after the procedure. Result Among 1,533 patients, 26 were dialysis patients and 1,504 were non-dialysis patients. 1,386 people (90.5%) succeeded in puncture. Radial artery occlusion occurred in 7 patients (0.4%), all of whom were non-dialysis patients. There was no significant difference of RAO rate in dialysis patients and non-dialysis patients. Conclusion When performing DRA puncture, the probability of radial artery occlusion is not higher in dialysis patients than non-dialysis patients. The DRA puncture may be one of the option as puncture site even in dialysis patients.

scholarly journals The frequency of radial artery occlusion following cardiac catheterization with the use of transradial pneumatic compression band

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Kashif Ali Hashmi ◽  
Zahid Iqbal ◽  
Atif Ali Hashmi ◽  
Maira Shoaib ◽  
Muhammad Irfan ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Radial Artery ◽  
Cardiac Catheterization ◽  
Age Groups ◽  
Vascular Complications ◽  
Artery Occlusion ◽  
Study Cohort ◽  
Coronary Catheterization ◽  
Significant Difference ◽  
Radial Artery Occlusion

Abstract Objectives Radial artery occlusion is a silent complication of a transradial approach to cardiac catheterization that may complicate subsequent transradial procedures in patients undergoing cardiac catheterization. A transradial band reduces vascular complications and provides brisk, powerful and effective haemostasis. The purpose of this study was to assess the frequency of radial artery occlusion in 180 patients undergoing transradial coronary catheterization. Results The median age of the study cohort was 58 years. Radial artery occlusion was found in 14 (7.8%) patients. When stratifying by age group and sex, there was no significant difference in radial artery occlusion between age groups and sex. It was likewise found that comorbidities such as diabetes mellitus, hypertension and smoking, increased the risk of radial artery occlusion however this was observed to be significant only for diabetes mellitus. We therefore conclude that a transradial pneumatic pressure band is an extremely helpful and safe strategy to prevent radial artery occlusion.

scholarly journals Efficacy of a novel topical combination of esafoxolaner, eprinomectin and praziquantel against Echinococcus multilocularis infections in cats

Parasite ◽  
2021 ◽  
Vol 28 ◽  
pp. 29
Author(s):  
Joe Prullage ◽  
Dwight Bowman ◽  
Michael Ulrich ◽  
Eric Tielemans
Keyword(s):  
Echinococcus Multilocularis ◽  
Experimental Studies ◽  
The United States ◽  
Treated Group ◽  
Control Group ◽  
Placebo Control ◽  
The Novel ◽  
Control Groups ◽  
Geometric Means ◽  
Placebo Control Group

NexGard® Combo, a novel topical endectoparasiticide formulation for cats combining esafoxolaner, eprinomectin and praziquantel, for the treatment of internal and external parasite infestations, including arthropods, nematodes and cestodes, was tested for efficacy against induced infections of Echinococcus multilocularis in cats, in two experimental studies. The two studies were performed in the United States with the same E. multilocularis isolate sourced locally. In each study, 20 cats were inoculated intra-gastrically with ~30,000 E. multilocularis protoscoleces three weeks before treatment, then ten cats were randomly allocated to a placebo control group or to the novel formulation treated group. Inoculated cats were treated topically once at the minimum recommended dose of the novel formulation, or with an identical volume of placebo. One week after treatment, cats were humanely euthanized for parasite recovery and count. The efficacy calculation was based on comparison of number of scoleces found in the control group and the novel formulation group. In the two control groups, E. multilocularis scoleces were found in five (range: 30–1025) and eight (range 2–345) cats, the geometric means inclusive of the ten cats per group were 8.9 and 28.8, respectively. In the two novel formulation-treated groups, none of the cats harbored any E. multilocularis scoleces, demonstrating 100% efficacy.

scholarly journals Radial artery occlusion after transradial coronary catheterization

2017 ◽  
Vol 7 (3) ◽  
pp. 305-316 ◽  
Author(s):  
Grigorios Avdikos ◽  
Aris Karatasakis ◽  
Andreas Tsoumeleas ◽  
Efstathios Lazaris ◽  
Antonios Ziakas ◽  
...  
Keyword(s):  
Radial Artery ◽  
Artery Occlusion ◽  
Coronary Catheterization ◽  
Radial Artery Occlusion
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