scholarly journals High‐Resolution Mapping and Ablation of Atrial Tachycardias Involving the Lateral Left Atrium

Author(s):  
Shinsuke Miyazaki ◽  
Kanae Hasegawa ◽  
Kazuya Yamao ◽  
Moe Mukai ◽  
Daisetsu Aoyama ◽  
...  

Background The lateral left atrium (LA) is often associated with atrial tachycardia (AT) because of its complex anatomy. We sought to characterize ATs associated with the lateral LA, including the posterolateral mitral isthmus (MI) and left atrial ridge. Methods and Results Twenty‐eight lateral LA‐associated ATs were mapped with high‐resolution mapping systems and entrainment pacing. The vein of Marshall was mapped with a 1.8‐Fr mapping catheter when possible. ATs were associated with the posterolateral MI in 18 ATs (14 perimitral, 3 small reentry, and 1 focal AT). All patients had undergone MI area ablation, and all ATs were successfully eliminated. During 27.0 (interquartile range, 10.5–40.0) months of follow‐up, all were free from any atrial tachyarrhythmias, with 3 patients on antiarrhythmics. Of 10 ATs involving the ridge or Marshall bundle, 3 were ridge related, 3 were Marshall bundle related based on vein of Marshall mapping, and 1 was a persistent left superior vena cava related AT. All 7 patients had undergone MI linear ablation. The critical isthmus was in the LA‐ridge junction or the LA‐Marshall bundle junction. Bidirectional conduction block between the LA and ridge or Marshall bundle was created. Two patients had the critical isthmus in the other area. The remaining patient had micro‐reentry in the ridge. All 10 ATs were terminated during ablation at the critical isthmus. During 12.0 (5.2–31.7) months of follow‐up, all were free from any atrial tachyarrhythmias, with 7 patients on antiarrhythmics. Conclusions Most ATs occurred after MI area ablation. An high resolution mapping‐guided approach is highly effective for identifying the mechanism.

2018 ◽  
Vol 82 (8) ◽  
pp. 2007-2015 ◽  
Author(s):  
Yasuaki Tanaka ◽  
Atsushi Takahashi ◽  
Takamitsu Takagi ◽  
Jun Nakajima ◽  
Katsumasa Takagi ◽  
...  

Heart Rhythm ◽  
2018 ◽  
Vol 15 (2) ◽  
pp. 193-200 ◽  
Author(s):  
Seigo Yamashita ◽  
Michifumi Tokuda ◽  
Ryota Isogai ◽  
Kenichi Tokutake ◽  
Kenichi Yokoyama ◽  
...  

2020 ◽  
Vol 127 (Suppl_1) ◽  
Author(s):  
Hanjay Wang ◽  
Terrence Pong ◽  
Haley Lucian ◽  
Joy Aparicio-Valenzuela ◽  
Yuko Tada ◽  
...  

Introduction: Newborn piglets reportedly exhibit natural heart regeneration after myocardial infarction (MI). However, the electrophysiologic properties of this regenerated muscle have not been examined. We hypothesized that epicardial electrical conduction is preserved after MI in newborn piglets. Methods: Yorkshire-Landrace piglets underwent left anterior descending coronary artery ligation on postnatal day 1 (P1, n=4) or postnatal day 7 (P7, n=7), infarcting the anteroseptal left ventricle through which the Purkinje conduction system passes. After 7 weeks, cardiac magnetic resonance imaging (MRI) was performed with late gadolinium enhancement for fibrosis analysis. Epicardial conduction mapping was performed using custom 3D-printed, 256-channel high-resolution mapping arrays (Fig 1A). Age- and weight-matched healthy pigs served as controls (n=7). Data are expressed as mean±SD. Results: MRI analysis revealed significant differences between the control, P1, and P7 groups in ejection fraction (47.6±3.1% vs 37.6±3.3% vs 30.2±6.6%, p<0.001, Fig 1B) and the degree of transmural anteroseptal LV scar (0.0±0.0% vs 9.1±5.4% vs 15.4±4.2%, p<0.001), respectively. Evidence of infarcted myocardium was identified with high-resolution mapping in the P1 and P7 piglets (black arrows, Fig 1C-F). Epicardial electrical conduction was preserved in control and all P1 pigs (Figs 1C-D), whereas variable conduction block or aberrant propagation were observed in all P7 pigs (Fig 1E-F, p=0.001). Conclusion: P1 piglets exhibited incomplete natural cardiac regeneration after MI but nevertheless demonstrated electrophysiologic conservation of epicardial conduction dynamics.


2020 ◽  
Vol 4 (5) ◽  
pp. 1-4
Author(s):  
Tomoyuki Arai ◽  
Rintaro Hojo ◽  
Takeshi Kitamura ◽  
Seiji Fukamizu

Abstract Background Superior vena cava (SVC) isolation has improved the outcomes of paroxysmal atrial fibrillation (AF) originating from the SVC. However, right phrenic nerve (PN) injury is a major complication of this procedure. Therefore, in cases where the right atrium (RA)-SVC conduction site is near the PN, tremendous care is required to prevent PN injury. Case summary Repeated SVC isolation was performed due to the recurrence of SVC-triggered AF. The RA-SVC activation map revealed that the partial conduction block line was detected, and the propagation broke through the gap at the course of the PN site from the RA to the SVC. Since the course of the PN identified at high-output pacing was wide, the SVC was isolated by making longitudinal lines on both sides of the PN in a cranial direction, except for where low-output pacing captured, confirming compound muscle action potential to detect PN injury. Eventually, the SVC was successfully isolated without PN injury, and the sinus rhythm was maintained without antiarrhythmic drugs during a 14-month follow-up period. Conclusion Superior vena cava isolation was difficult depending on the course of the PN, and some methods to avoid PN injury were reported. However, this method can facilitate safe and effective SVC isolation with the conventional system, including the cases with AF foci located on the course of the PN.


1996 ◽  
Vol 270 (4) ◽  
pp. F567-F574 ◽  
Author(s):  
W. J. Lammers ◽  
H. R. Ahmad ◽  
K. Arafat

In renal pelvis preparations isolated from the sheep, the location of the pacemaker and the pathway of conduction of the electrical impulse in the pelvis were analyzed in detail. An electrophysiological acquisition system was used allowing simultaneous recordings from 240 extracellular electrodes. Reconstruction of the spread of activity showed that the site of the pelvis pacemaker was, in virtually all cases, located at the pelvicalyceal border and never in the body of the pelvis or in the area of the pelviureteric junction. One single pacemaker was responsible for a particular spread of activation, and fusion of activity originating from two or more pacemakers did not place. Furthermore, spontaneous shifts of the pacemaker could occur from one site to another along the pelvicalyceal border. Conduction from the site of the current pacemaker to the pelviureteric junction and the ureter was slow, inhomogeneous, and contorted. Multiple instances of partial or total conduction block were seen at all levels in the pelvis and were not restricted to the pelviureteric junction. The occurrence of the conduction block did not seem to be related to the length of the preceding interval, implying that the refractory period did not play a major role in the genesis of intrapelvic conduction block. In conclusion, high-resolution mapping of the renal pelvis is possible and reveals location and behavior of the pacemaker and documents inhomogeneities in conduction and conduction block.


EP Europace ◽  
2017 ◽  
Vol 19 (suppl_3) ◽  
pp. iii29-iii30
Author(s):  
S. Honarbakhsh ◽  
W. Ullah ◽  
E. Keating ◽  
G. Dhillon ◽  
M. Finlay ◽  
...  

1990 ◽  
Vol 123 ◽  
pp. 297-306
Author(s):  
Geoffrey A. Briggs

After a decade long hiatus in launches beyond Earth orbit, NASA’s planetary exploration program is again moving forward, beginning with the Magellan launch to Venus in May 1989 and the Galileo launch to Jupiter in October 1989. These spacecraft will reach their targets in August 1990 and December 1995, respectively. Both are missions of longstanding priority, Magellan to provide the first global high resolution mapping of the cloud-shrouded Venus surface, Galileo to make comprehensive measurements of the Jovian system in follow-up to the 1979/1980 Voyager flybys.Beyond these two missions there are other already approved missions: the Mars Observer for launch in 1992, the Comet Rendezvous and Asteroid Flyby CRAF mission (Fig. 1) for launch in 1995, and the Cassini mission (Figs. 2 and 3) to Saturn and its moon Titan for launch in 1996. The very diversity of these five missions and their targets (Venus, the Jovian system, Mars, comet Kopff, asteroids Gaspra and Ida by Galileo, Hamburga by CRAF, and Maja by Cassini, and the Saturnian system, is indicative of the strategy being pursued in the program: one of deliberate breadth that seeks to explore all three main classes of solar system bodies (the terrestrial planets, the outer giants and their moons, and the primitive small bodies).


Sign in / Sign up

Export Citation Format

Share Document