Abstract WMP43: Bright Signals of MCA Plaque on T2 Weighted Vessel Wall Imaging are Associated With Ischemic Stroke

Stroke ◽  
2018 ◽  
Vol 49 (Suppl_1) ◽  
Author(s):  
Yannan Yu ◽  
Mengwei Liu ◽  
Mingli Li ◽  
Yuyuan Xu ◽  
Shan Gao ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Vessel Wall ◽  
Vessel Wall Imaging ◽  
Wall Imaging

scholarly journals MRI Vessel Wall Imaging after Intra-Arterial Treatment for Acute Ischemic Stroke

2020 ◽  
Vol 41 (4) ◽  
pp. 624-631
Author(s):  
A. Lindenholz ◽  
I.C. van der Schaaf ◽  
A.G. van der Kolk ◽  
H.B. van der Worp ◽  
A.A. Harteveld ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Vessel Wall ◽  
Vessel Wall Imaging ◽  
Wall Imaging

Middle cerebral artery geometric features are associated with plaque distribution and stroke

Neurology ◽  
2018 ◽  
Vol 91 (19) ◽  
pp. e1760-e1769 ◽  
Author(s):  
Yan Nan Yu ◽  
Ming-Li Li ◽  
Yu-Yuan Xu ◽  
Yao Meng ◽  
Harry Trieu ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Confidence Interval ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Odds Ratio ◽  
Vessel Wall ◽  
Vessel Wall Imaging ◽  
Geometric Features ◽  
Insight Into ◽  
Wall Imaging

ObjectiveWe aimed to investigate the geometric features of the middle cerebral artery (MCA) and their relevance to plaque distribution and ischemic stroke.MethodsWe reviewed our institutional vessel wall imaging database. Patients with symptomatic MCA atherosclerosis, asymptomatic MCA atherosclerosis, or without MCA atherosclerosis were included. The MCA geometric features, including M1 segment shape and M1 curve orientation, were defined on magnetic resonance angiography. Plaque distribution and other plaque parameters were identified on vessel wall imaging. The association among MCA geometric features, plaque distribution, and ischemic stroke were analyzed.ResultsA total of 977 MCAs were analyzed (87 atherosclerotic symptomatic MCAs, 459 atherosclerotic asymptomatic MCAs, and 431 plaque-free MCAs). Overall, curved M1 segments were the predominant shape across all groups. In 91.1% of curved atherosclerotic MCAs, the plaque involved the inner wall of the curve. Plaque not involving the inner wall was shorter (p < 0.0001) and thinner (p = 0.005) compared to plaque involving the inner wall. Inferior plaque was observed in 39.9% of inferior-oriented M1 curves compared to 21.7% in non–inferior-oriented M1 curves (p < 0.0001). The absence of an inferior-oriented M1 curve (odds ratio 0.45, 95% confidence interval 0.27–0.77) and presence of superior plaque (odds ratio 2.67, 95% confidence interval 1.52–4.67) were independently associated with stroke after adjusting for plaque length and thickness, degree of stenosis, and remodeling ratio.ConclusionsMCA geometric features are associated with plaque distribution and stroke. Our findings provide insight into the vascular pathophysiology of MCA atherosclerosis.

The clinical value of head-neck joint high-resolution vessel wall imaging in ischemic stroke

2020 ◽  
Vol 29 (9) ◽  
pp. 105062
Author(s):  
Ming-Li Li ◽  
Qian-Qian Lin ◽  
Yi-Tong Liu ◽  
Bo Hou ◽  
Feng Feng ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
High Resolution ◽  
Vessel Wall ◽  
Vessel Wall Imaging ◽  
Clinical Value ◽  
Head Neck ◽  
Wall Imaging

Abstract WMP44: Differential Middle Cerebral Artery Plaque Characteristics in Patients With Transient Ischemic Attack and Ischemic Stroke: A High-Resolution MR Vessel Wall Imaging Study

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Jiayu Xiao ◽  
Matthew Padrick ◽  
Qi Yang ◽  
Tao Jiang ◽  
Shuang Xia ◽  
...  
Keyword(s):  
Risk Factor ◽  
Ischemic Stroke ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Transient Ischemic Attack ◽  
Vessel Wall ◽  
Vessel Wall Imaging ◽  
Plaque Burden ◽  
Ischemic Attack ◽  
Wall Imaging

Introduction: Intracranial atherosclerotic disease (ICAD) correlates highly with transient ischemic attack (TIA) and acute ischemic stroke (AIS). Magnetic Resonance (MR) vessel wall imaging (VWI) is an emerging non-invasive imaging modality for directly assessing ICAD lesions. Methods: We retrospectively analyzed MR-VWI from 42 TIA patients and 45 AIS patients with ICAD. All patients fulfilled the following criteria: (1) stenosis >30% of a middle cerebral artery (MCA), (2) symptoms contralateral to stenotic MCA, (3) no coexisting stenosis at other major vessels; (4) lack of compelling evidence to other etiologies of stroke/TIA. Vascular lesions were analyzed with MR-VWI with respect to the stenosis degree, vessel wall irregularity, plaque burden (PB), remodeling index (RI), plaque-wall contrast ratio (CR) and plaque enhancement grade (EG). Results: EG (OR 3.88, 95%CI 1.42-10.57, P=0.006) was a risk factor for AIS while PB (OR 0.65, 95%CI 0.27-1.54, P=0.008) was a risk factor for TIA. In patients with 30-70% degree stenosis, CR (OR 5.38, 95%CI 1.39-20.75, P=0.008) was a risk factor for stroke, while PB (OR 0.4, 95%CI 0.1-1.65, P=0.006) remained a risk factor for TIA. Conclusions: In our study, PB appeared as a risk factor for TIA but not for AIS. This suggests that unstable plaque accounting for AIS may have a wide range of PB. We further found that CR and EG are more associated with AIS than TIA. Lesions with high CR and strong enhancement may be more prone to producing the permanent ischemic injury. Further study is needed to elucidate the role of MR-VWI in differential diagnosis and management of TIA and AIS.

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