Recent developments of collagen-based materials for medical applications and drug delivery systems

1996 ◽  
Vol 7 (7) ◽  
pp. 623-645 ◽  
Author(s):  
K. Panduranga Rao
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Medical Applications ◽  
Recent Developments

scholarly journals Food-Derived Nanoscopic Drug Delivery Systems for Treatment of Rheumatoid Arthritis

Molecules ◽  
2020 ◽  
Vol 25 (15) ◽  
pp. 3506
Author(s):  
Dong Han ◽  
Qilei Chen ◽  
Hubiao Chen
Keyword(s):  
Rheumatoid Arthritis ◽  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Drug Carriers ◽  
Delivery Systems ◽  
Bioactive Molecules ◽  
Research Orientation ◽  
Therapeutic Outcomes ◽  
Systemic Inflammatory Disease ◽  
Recent Developments

Rheumatoid arthritis (RA) is a severe systemic inflammatory disease with no cure at present. Recent developments in the understanding of inflammation and nanomaterial science have led to increased applications of nanostructured drug delivery systems in the treatment of RA. The present review summarizes novel fabrications of nanoscale drug carriers using food components as either the delivered drugs or carrier structures, in order to achieve safe, effective and convenient drug administration. Polyphenols and flavonoids are among the most frequently carried anti-RA therapeutics in the nanosystems. Fatty substances, polysaccharides, and peptides/proteins can function as structuring agents of the nanocarriers. Frequently used nanostructures include nanoemulsions, nanocapsules, liposomes, and various nanoparticles. Using these nanostructures has improved drug solubility, absorption, biodistribution, stability, targeted accumulation, and release. Joint vectorization, i.e., using a combination of bioactive molecules, can bring elevated therapeutic outcomes. Utilization of anti-arthritic chemicals that can self-assemble into nanostructures is a promising research orientation in this field.

Whey protein: A functional and promising material for drug delivery systems recent developments and future prospects

2019 ◽  
Vol 30 (9) ◽  
pp. 2183-2191 ◽  
Author(s):  
Muhammad Asim Farooq ◽  
Md Aquib ◽  
Sana Ghayas ◽  
Rabia Bushra ◽  
Daulat Haleem Khan ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Whey Protein ◽  
Drug Delivery Systems ◽  
Protein A ◽  
Delivery Systems ◽  
Promising Material ◽  
Future Prospects ◽  
Recent Developments

Implant-associated local drug delivery systems for different medical applications

2012 ◽  
Vol 57 (SI-1 Track-S) ◽  
Author(s):  
K. Sternberg ◽  
S. Petersen ◽  
N. Grabow ◽  
F. Luderer ◽  
A. Bohl ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Local Drug Delivery ◽  
Medical Applications

Inorganic-organic Nanomaterials for Therapeutics and Molecular Imaging Applications

2020 ◽  
Vol 10 (6) ◽  
pp. 748-765
Author(s):  
Alaa A.A. Aljabali ◽  
Mohammad A. Obeid
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Cell Labeling ◽  
Bibliographic Databases ◽  
Medical Applications ◽  
Advantages And Disadvantages ◽  
Naturally Occurring

Background:: Surface modification of nanoparticles with targeting moieties can be achieved through bioconjugation chemistries to impart new Functionalities. Various polymeric nanoparticles have been used for the formulation of nanoparticles such as naturally-occurring protein cages, virus-like particles, polymeric saccharides, and liposomes. These polymers have been proven to be biocompatible, side effects free and degradable with no toxicity. Objectives:: This paper reviews available literature on the nanoparticles pharmaceutical and medical applications. The review highlights and updates the customized solutions for selective drug delivery systems that allow high-affinity binding between nanoparticles and the target receptors. Methods:: Bibliographic databases and web-search engines were used to retrieve studies that assessed the usability of nanoparticles in the pharmaceutical and medical fields. Data were extracted on each system in vivo and in vitro applications, its advantages and disadvantages, and its ability to be chemically and genetically modified to impart new functionalities. Finally, a comparison between naturally occurring and their synthetic counterparts was carried out. Results:: The results showed that nanoparticles-based systems could have promising applications in diagnostics, cell labeling, contrast agents (Magnetic Resonance Imaging and Computed Tomography), antimicrobial agents, and as drug delivery systems. However, precautions should be taken to avoid or minimize toxic effect or incompatibility of nanoparticles-based systems with the biological systems in case of pharmaceutical or medical applications. Conclusion:: This review presented a summary of recent developments in the field of pharmaceutical nanotechnology and highlighted the challenges and the merits that some of the nanoparticles- based systems both in vivo and in vitro systems.

Sign in / Sign up

Export Citation Format

Share Document