Forced Expiratory Volume In One Second (FEV1) Can Predict Hospitalizations Due To Acute Exacerbations Of Chronic Obstructive Pulmonary Disease (AECOPD) And Coronary Heart Disease (CHD) In Patients With Chronic Obstructive Pulmonary Disease (COPD)

2011 ◽  
Author(s):  
Mumtaz U. Zaman
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Pulmonary Disease ◽  
Forced Expiratory Volume ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Acute Exacerbations

scholarly journals Factors Associated with Hospital Admission in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease in a Teaching Hospital

2018 ◽  
Vol 28 (2) ◽  
pp. 52-57
Author(s):  
Md Nure Alom Siddiqui ◽  
Shahnaj Sultana ◽  
MMR Khan ◽  
PM Basak
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Hospital Admissions ◽  
Forced Expiratory Volume ◽  
Chronic Obstructive ◽  
Related Factors ◽  
Obstructive Pulmonary Disease ◽  
Factors Associated ◽  
Acute Exacerbations

Background: Acute exacerbations of chronic obstructive pulmonary disease (AE-COPD) impair quality of life (QOL), accelerate the decline in lung function and often require hospitalization, and thus, leading to increased healthcare burden. By identifying factors that may be associated with AE-COPD and managing them rationally, not only the hospital admissions could be avoided but progression of the disease may also be slowed.Objective. The aim of the present study was to determine the factors associated with hospital admissions among adults with AE-COPD.Methods. Seventy-three patients admitted with AE-COPD were administered a structured questionnaire during their hospital stay. Data on body mass index (BMI), smoking, symptoms, co-morbidities course of the disease, spirometry management and outcomes during the hospitalisation were obtained. Factors associated with hospital admissions were analyzed.Results. The hospitalization due to AE-COPD was significantly associated with the reduced forced expiratory volume in one second (FEV1), and peak expiratory flow rates, increasing sputum purulence, number of hospitalizations during previous year for COPD and presence of co-morbidities.Conclusions. The study shows that both disease and healthcare-related factors are predictors for hospitalisation. Identification of risk factors and appropriate management may reduce hospitalisation due to AE-COPD.TAJ 2015; 28(2): 52-57

scholarly journals THE PECULIARITIES OF THE COMBINED COURSE OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND CORONARY HEART DISEASE (LITERATURE REVIEW)

2021 ◽  
Vol 20 (2) ◽  
Author(s):  
Т.О. Ilashchuk ◽  
O.P. Mykytyuk ◽  
Y.V. Chobanu
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Pulmonary Disease ◽  
Therapeutic Strategies ◽  
Data Sources ◽  
Chronic Obstructive ◽  
Physiological Effects ◽  
Obstructive Pulmonary Disease ◽  
Promising Area

The aim – to analyze the literature data sources concerning the peculiarities of thecombined course of chronic obstructive pulmonary disease (COPD) and coronaryheart disease (CHD), taking into account the endothelial dysfunction of systemicinflammation and oxidative stress.Conclusions. The main mechanisms involved in the progression of the combinedcourse of chronic obstructive pulmonary disease and coronary heart disease are theendothelial dysfunction, the systemic inflammation and desynchronosis. The pleiotropiceffects and diverce molecular interactions of sirtuins have distinct physiological effects,such as preventing the development and progression of emphysema in COPD and avoiding the progression of myocardical hypertrophy and heart failure. The researchof intermolecular interactions with the help of Sirtuin is a promising area for findingnew effective diagnostic and prognostic criteria and therapeutic strategies for COPDand CVD.

scholarly journals Chinese Herbal Medicine (WeijingDecoction) Combined with Pharmacotherapy for the Treatment of Acute Exacerbations of Chronic Obstructive Pulmonary Disease

2014 ◽  
Vol 2014 ◽  
pp. 1-12 ◽  
Author(s):  
Shaonan Liu ◽  
Johannah Shergis ◽  
Xiankun Chen ◽  
Xuhua Yu ◽  
Xinfeng Guo ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Blood Gases ◽  
Effective Rate ◽  
Forced Expiratory Volume ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Randomized Controlled ◽  
Arterial Blood ◽  
Acute Exacerbations

Objective. To evaluate the efficacy and safety ofWeijingdecoction combined with routine pharmacotherapy (RP) for the treatment of acute exacerbations of chronic obstructive pulmonary disease (AECOPD).Methods. Randomized controlled trials (RCT) evaluatingWeijingdecoction for AECOPD were included. English, Chinese, and Japanese databases were searched from their respective inceptions to June 2013. The methodological quality was assessed according to the Cochrane Collaboration’s risk of bias tool. All data were analyzed and synthesized using RevMan 5.2 software.Results. Fifteen (15) studies involving 986 participants were included. Participants were diagnosed with COPD in the acute exacerbation stage. In addition, most of studies reported that they included participants with the Chinese medicine syndrome, phlegm-heat obstructing the Lung.Weijingdecoction combined with RP improved lung function (forced expiratory volume in one second; FEV1), arterial blood gases (PaO2 and PaCO2), clinical effective rate, and reduced inflammatory biomarkers (TNF-αand IL-8) when compared with RP alone. No severe adverse events were reported in these studies.Conclusions.Weijingdecoction appeared to be beneficial for AECOPD and well-tolerated when taken concurrently with RP, such as antibiotics, bronchodilators (oral and inhaled), and mucolytics.

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