scholarly journals Accuracy of Multiplanar MR Images in Determination of Actual Tumour Size in Comparison to the Pelvic Examination of Carcinoma Cervix

2021 ◽  
Vol 6 (3) ◽  
pp. 136
Author(s):  
Husnaion Zubery ◽  
Mahbuba Shirin ◽  
Falguni Binte Rahman ◽  
Biswajit Bhowmik ◽  
Mohammad Ibrahim ◽  
...  
Keyword(s):  
Tumour Size ◽  
Pelvic Examination ◽  
Mr Images ◽  
Carcinoma Cervix

scholarly journals Size of cervical lesion in locally advanced carcinoma cervix and response to neoadjuvant chemotherapy

2019 ◽  
Vol 8 (11) ◽  
pp. 4254
Author(s):  
Neetu Ahirwar
Keyword(s):  
Neoadjuvant Chemotherapy ◽  
Tumour Size ◽  
Locally Advanced ◽  
Vascular Supply ◽  
Cervical Lesion ◽  
Carcinoma Cervix ◽  
Advanced Carcinoma ◽  
Response To Chemotherapy ◽  
Treatment Volume ◽  
Pre Treatment

Background: Recently neoadjuvant chemotherapy has started being considered for advanced stage of carcinoma cervix. Drug delivery to pelvic tumour is optimal with neoadjuvant chemotherapy since tumour vascular supply has not been damaged by any previous pelvic interference. Tumor size and parametrial involvement have been reported to be important predictor of NACT response. Objective of this study was to find out association between size of cervical lesion in locally advanced carcinoma cervix and response to neoadjuvant chemotherapy.Methods: The present prospective cohort study was carried out in the Department of Obstetrics and Gynaecology with the collaboration of Department of Radiotherapy, Chhatrapati Shahuji Maharaj Medical University Lucknow for a period of 1-year august 2010 to august 2011. 26 patients with histologically proven locally advanced carcinoma cervix were studied. In all cases Cisplatin 75 mg/m2 and paclitaxel 135 mg/m2 on day one was given at 14 days interval up to maximum of three courses. Evaluation of operability status was done two weeks after second course of chemotherapy. Those found operable were taken up for radical hysterectomy and rest were given 3rd course of chemotherapy. After two weeks of 3rd course again operability assessment was done and patient was taken up either for surgery or radiotherapy.Results: It was observed that out of 14 patients who had tumour size <4 cm, 9 (64.2%) responded completely (CR), 2 (14.2%) responded partially and 3 (21.4%) responded as SD while in 12 patients with tumour size >4 cm, 4 (33.3%) responded completely (CR) and rest 8 (66.6%) response was partial (PR).Conclusions: Response to chemotherapy was modified by pre-treatment volume of the tumour.

scholarly journals Carcinoma Cervix- Significance of Tumour Size in Treatment Outcome

2019 ◽  
Vol 8 (33) ◽  
pp. 2629-2632
Author(s):  
Agarwal Amit ◽  
Agrawal Gaurav ◽  
Kumar Piyush ◽  
Sharma Manish Kumar ◽  
Patneedi Bhavya
Keyword(s):  
Treatment Outcome ◽  
Tumour Size ◽  
Carcinoma Cervix

scholarly journals Cautery artifact understages urothelial cancer at initial transurethral resection of large bladder tumours

2017 ◽  
Vol 11 (5) ◽  
pp. 203 ◽  
Author(s):  
Matthew Truong ◽  
Lorraine Liang ◽  
Janet Kukreja ◽  
Jeanne O’Brien ◽  
Jerome Jean-Gilles ◽  
...  
Keyword(s):  
Transurethral Resection ◽  
Urothelial Cancer ◽  
Tumour Size ◽  
Accurate Determination ◽  
Bladder Tumour ◽  
Billing Data ◽  
Accurate Staging ◽  
Resident Involvement ◽  
Bladder Tumours

Introduction: We sought to determine how frequently cautery (thermal) artifact precludes an accurate determination of stage at initial transurethral resection of bladder tumour (TURBT) of large bladder tumours.Methods: We queried our institution’s billing data to identify patients who underwent TURBT for large bladder tumours >5cm (CPT 52240) by two urologists at an academic centre from January 2009 through April 2013. Only patients who underwent initialstaging TURBT for urothelial cancer were included. Pathological reports were reviewed for stage, number of separate pathological specimens per TURBT, and presence of cautery artifact. Operative reports were reviewed for whether additional cold cup biopsies were taken of other suspicious areas of the bladder, resident involvement, and type of electrocautery.Results: We identified 119 patients who underwent initial staging TURBT for large tumours. Cautery artifact interfered with accurate staging in 7/119 (6%) of cases. Of these, six patients underwent restaging TURBT, with 50% percent experiencing upstaging to T2 disease. Tumour size, tumour grade, whether additional cold cup biopsies were taken, number of separate pathological specimens sent, and resident involvement were not associated with cautery artifact (all p>0.05). Bipolar resection had a higher rate of cautery artifact 5/42 (12%), compared to monopolar resection 2/77 (2.6%) approaching significance (p=0.095).Conclusions: Cautery artifact may delay accurate staging at initial TURBT for large tumours by understaging up to 6% of patients.

scholarly journals Automatic determination of MS lesion subtypes based on fractal analysis in brain MR images

2012 ◽  
Vol 05 (04) ◽  
pp. 162-169
Author(s):  
Mahdi Mohamadkhanloo ◽  
Farzad Mehrabi ◽  
Abdolhamid Sohrabi
Keyword(s):  
Fractal Analysis ◽  
Mr Images ◽  
Automatic Determination ◽  
Brain Mr Images

Reliability of postoperative MR imaging in the determination of level and side of lumbar spinal decompression surgery

2016 ◽  
Vol 58 (5) ◽  
pp. 581-585
Author(s):  
Florian Wanivenhaus ◽  
Florian M Buck ◽  
Michael Betz ◽  
Nadja A Farshad-Amacker ◽  
Mazda Farshad
Keyword(s):  
High Reliability ◽  
Surgical Decompression ◽  
Time Interval ◽  
Decompression Surgery ◽  
Mr Images ◽  
Spinal Decompression ◽  
Lumbar Spinal ◽  
Lumbar Spinal Decompression ◽  
Musculoskeletal Radiologist

Background Magnetic resonance imaging (MRI) is the diagnostic modality of choice in defining soft tissue compromise of the spinal canal. Purpose To evaluate the reliability of postoperative MRI in the determination of level and side of lumbar spinal decompression surgery, investigated by two reviewers, in different levels of training and specialization. Material and Methods Postoperative MR images of 86 patients who underwent spinal decompression (single level, n = 70; multilevel, n = 16; revision decompression, n = 9) were reviewed independently by an experienced musculoskeletal radiologist and a fourth-year orthopedic surgery resident. The level (single or multiple) and side of previous surgical decompression were determined and compared to the surgical notes. We examined factors that may have influenced the reliability, including demographics, type of surgical decompression, use of a drain, and time interval from surgery to MRI. Results Significantly fewer levels were correctly determined by the resident (77/86 cases, 89.5%) compared with the radiologist (84/86 cases, 97.7%) ( P = 0.014). The resident interpreted significantly more MR images incorrectly in cases where a drain was used (n = 8; P < 0.001). Re-decompression cases were interpreted incorrectly significantly more often by both the radiologist (n = 2, P = 0.032) and the resident (n = 4, P = 0.014). Conclusion Determination of the level and side operated on in previous lumbar spinal decompression surgery on MRI has a high reliability, especially when performed by a musculoskeletal radiologist. However, this reliability is decreased in cases involving surgical drainage and same-level revision surgery.

scholarly journals MRI-based 3D retinal shape determination

2021 ◽  
Vol 6 (1) ◽  
pp. e000855
Author(s):  
Luc van Vught ◽  
Denis P Shamonin ◽  
Gregorius P M Luyten ◽  
Berend C Stoel ◽  
Jan-Willem M Beenakker
Keyword(s):  
Three Dimensional ◽  
Good Method ◽  
Peripheral Retina ◽  
Mr Images ◽  
Central Retina ◽  
Complete Procedure ◽  
The Mean ◽  
Shape Determination ◽  
Posterior Shift

ObjectiveTo establish a good method to determine the retinal shape from MRI using three-dimensional (3D) ellipsoids as well as evaluate its reproducibility.Methods and analysisThe left eyes of 31 volunteers were imaged using high-resolution ocular MRI. The 3D MR-images were segmented and ellipsoids were fitted to the resulting contours. The dependency of the resulting ellipsoid parameters on the evaluated fraction of the retinal contour was assessed by fitting ellipsoids to 41 different fractions. Furthermore, the reproducibility of the complete procedure was evaluated in four subjects. Finally, a comparison with conventional two-dimensional (2D) methods was made.ResultsThe mean distance between the fitted ellipsoids and the segmented retinal contour was 0.03±0.01 mm (mean±SD) for the central retina and 0.13±0.03 mm for the peripheral retina. For the central retina, the resulting ellipsoid radii were 12.9±0.9, 13.7±1.5 and 12.2±1.2 mm along the horizontal, vertical and central axes. For the peripheral retina, these radii decreased to 11.9±0.6, 11.6±0.4 and 10.4±0.7 mm, which was accompanied by a mean 1.8 mm posterior shift of the ellipsoid centre. The reproducibility of the ellipsoid fitting was 0.3±1.2 mm for the central retina and 0.0±0.1 mm for the peripheral retina. When 2D methods were used to fit the peripheral retina, the fitted radii differed a mean 0.1±0.1 mm from the 3D method.ConclusionAn accurate and reproducible determination of the 3D retinal shape based on MRI is provided together with 2D alternatives, enabling wider use of this method in the field of ophthalmology.

Rapid magnetic resonance imaging–guided reduction of craniovertebral junction deformities

2009 ◽  
Vol 10 (1) ◽  
pp. 27-32 ◽  
Author(s):  
Tim E. Darsaut ◽  
Muthana M. Sartawi ◽  
Perry Dhaliwal ◽  
Richard J. Fox
Keyword(s):  
Mr Imaging ◽  
Soft Tissues ◽  
Craniovertebral Junction ◽  
Resonance Imaging ◽  
Mr Images ◽  
Rapid Reduction ◽  
Plain Radiographs ◽  
Sequential Addition ◽  
Spine Board

The authors demonstrate the utility of an MR imaging–compatible traction board for the rapid reduction of craniovertebral junction (CVJ) deformities. To choose the appropriate surgical management, patients with compressive CVJ deformities often undergo a trial of traction. Conventional traction trials require the treating surgeon to infer from plain radiographs the manner in which traction forces affect neural and ligamentous structures at the CVJ. To avoid overdistraction injury, low increments of weight are added in a gradual fashion, a process that typically requires 48–72 hours. The authors outline the use of an MR imaging–compatible traction board to determine reducibility safely and rapidly in 4 patients with compressive CVJ deformities. Four patients with advanced CVJ deformities underwent a trial of MR imaging–guided traction performed using an MR imaging–compatible spine board. Serial sagittal images were acquired at baseline and following each sequential addition of force. All patients tolerated traction without neurological worsening. The neural elements were seen to be adequately decompressed in all cases during a single MR imaging session. Patients subsequently underwent craniocervical stabilization and fusion. Postoperative imaging showed maintenance of the reduction without neural compression. An MR imaging–guided trial of traction can facilitate the rapid and safe determination of the reducibility of compressive lesions in patients with advanced CVJ deformities. Rapidly acquired sagittal MR images permit the surgeon to evaluate the effects of traction on the soft tissues at the CVJ, thereby expediting the traction trial and avoiding the risks of immobility in this often-fragile patient population.

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