scholarly journals Research Status of Three-Dimensional Pseudo-Continuous Arterial Spin Labeling in Ischemic Cerebrovascular Diseases

2018 ◽  
Vol 4 (1) ◽  
pp. 1
Author(s):  
Lina Zhu
Keyword(s):  
Arterial Spin Labeling ◽  
Three Dimensional ◽  
Spin Labeling ◽  
Cerebrovascular Diseases ◽  
Research Status ◽  
Ischemic Cerebrovascular Diseases ◽  
Continuous Arterial Spin Labeling

scholarly journals Collateral perfusion using arterial spin labeling in symptomatic versus asymptomatic middle cerebral artery stenosis

2017 ◽  
Vol 39 (1) ◽  
pp. 108-117 ◽  
Author(s):  
Xin Lou ◽  
Xiaoxiao Ma ◽  
David S Liebeskind ◽  
Ning Ma ◽  
Chenglin Tian ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Arterial Spin Labeling ◽  
Three Dimensional ◽  
Spin Labeling ◽  
Asymptomatic Group ◽  
Asymptomatic Patients ◽  
The Difference ◽  
Continuous Arterial Spin Labeling ◽  
Antegrade Flow

The purpose was to assess the difference of collaterals in symptomatic versus asymptomatic patients with unilateral middle cerebral artery (MCA) stenosis by comparing cerebral blood flow (CBF) at two post labeling delays (PLD) using three-dimensional pseudo-continuous arterial spin labeling (3D pCASL). Eighty-one patients (49 symptomatic and 32 asymptomatic) with unilateral MCA stenosis ≥50% who underwent pCASL with two PLDs were included. Mean CBF and CBF subtraction images between two PLDs of MCA territories were compared in symptomatic and asymptomatic groups, respectively. Compared with the asymptomatic group, patients with symptomatic MCA stenosis had significantly lower CBF in the MCA territory of stenotic side at each PLD. The CBF of stenotic territory showed greater increase than that of normal side from PLD 1.5 to 2.5 s. The CBF of asymptomatic MCA territory increased similarly with that of symptomatic MCA territory from PLD of 1.5 to 2.5 s in stenotic side, while symptomatic patients experienced significantly slower antegrade flow. On CBF subtraction images, asymptomatic patients showed larger volume of differences between PLD of 1.5 and 2.5 s compared with those of symptomatic patients ( p = 0.037). The results suggest that more robust collateral perfusion on two-delay 3D pCASL is present in asymptomatic patients compared with symptomatic patients.

scholarly journals Cerebaral Hyperperfusion in  General Paralysis Patients

2020 ◽  
Author(s):  
Yali Wu ◽  
jingjing li ◽  
wenqing wu
Keyword(s):  
Blood Flow ◽  
Healthy Subjects ◽  
Arterial Spin Labeling ◽  
Parietal Lobe ◽  
Three Dimensional ◽  
Occipital Lobe ◽  
Spin Labeling ◽  
General Paralysis ◽  
Limbic Lobe ◽  
Continuous Arterial Spin Labeling

Abstract Objective This study aimed to identify the cerebral blood flow (CBF) in patients with general paralysis (GP). Methods Three-dimensional pseudo-continuous arterial spin labeling (3D-pCASL) imaging was performed to measure the CBF in twenty patients with GP and twenty healthy subjects(NC). CBF was normalized to reduce variations among subjects. CBF was compared between the groups. Results Compared with the healthy subjects, the patients with GP exhibited increased CBF in the frontal lobe, temporal lobe, insular lobe, limbic lobe, and parietal lobe(all P<0.05). There was no difference in CBF of the occipital lobe between the GP group and the NC group(all P>0.05). Conclusions Our results suggest that the patients with GP may exhibit regional increased CBF, which may be one of the pathogenesis of general paralysis.

scholarly journals Reliability of Three-Dimensional Pseudo-Continuous Arterial Spin Labeling MR Imaging for Measuring Visual Cortex Perfusion on Two 3T Scanners

PLoS ONE ◽  
2013 ◽  
Vol 8 (11) ◽  
pp. e79471 ◽  
Author(s):  
Diandian Huang ◽  
Bing Wu ◽  
Kaining Shi ◽  
Lin Ma ◽  
Youquan Cai ◽  
...  
Keyword(s):  
Visual Cortex ◽  
Mr Imaging ◽  
Arterial Spin Labeling ◽  
Three Dimensional ◽  
Spin Labeling ◽  
Continuous Arterial Spin Labeling

scholarly journals Test–retest reliability of perfusion of the precentral cortex and precentral subcortical white matter on three-dimensional pseudo-continuous arterial spin labeling

2018 ◽  
Vol 46 (9) ◽  
pp. 3788-3795
Author(s):  
Mengqi Liu ◽  
Zhiye Chen ◽  
Lin Ma
Keyword(s):  
White Matter ◽  
Resting State ◽  
Arterial Spin Labeling ◽  
Three Dimensional ◽  
Spin Labeling ◽  
Subcortical White Matter ◽  
Finger Tapping ◽  
Retest Reliability ◽  
Continuous Arterial Spin Labeling ◽  
Test Retest Reliability

Objective This study was performed to evaluate the test–retest reliability of perfusion of the cortex and subcortical white matter on three-dimensional spiral fast spin echo pseudo-continuous arterial spin labeling (3D-ASL). Methods Eight healthy subjects underwent 3D-ASL and structural imaging at the same time each day for 1 week. ASL data acquisition was performed in the resting state and right finger-tapping state. Cerebral blood flow (CBF) images were calculated, and the CBF values of the precentral cortex (PCC) and precentral subcortical white matter (PCSWM) were automatically extracted based on the structural images and CBF images. Results In the resting state, the intraclass correlation coefficient (ICC) of the bilateral PCC was 0.84 (left) and 0.81 (right) and that of the bilateral SCWM was 0.89 (left) and 0.85 (right). In the finger-tapping state, the ICC of the bilateral PCC was 0.91 (left) and 0.87 (right) and that of the bilateral PCSWM was 0.87 (left) and 0.92 (right). The CBF value of the left PCC and PCSWM was not significantly different between the resting state and finger-tapping state on two ASL scans. Conclusion 3D-ASL provides reliable CBF measurement in the cortex and subcortical white matter in the resting or controlled state.

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