scholarly journals Dorsomedial/Perifornical Hypothalamic Stimulation Increases Intraocular Pressure, Intracranial Pressure, and the Translaminar Pressure Gradient

2012 ◽  
Vol 53 (11) ◽  
pp. 7328 ◽  
Author(s):  
Brian C. Samuels ◽  
Nathan M. Hammes ◽  
Philip L. Johnson ◽  
Anantha Shekhar ◽  
Stuart J. McKinnon ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Intracranial Pressure ◽  
Pressure Gradient ◽  
Hypothalamic Stimulation

Author Response: Retinal Vein Pulsation Is in Phase with Intracranial Pressure and Not Intraocular Pressure

2012 ◽  
Vol 53 (11) ◽  
pp. 6880 ◽  
Author(s):  
William H. Morgan ◽  
Christopher R. P. Lind ◽  
Samuel Kain ◽  
Naeem Fatehee ◽  
Arul Bala ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Intracranial Pressure ◽  
Author Response

scholarly journals Intraocular pressure vs intracranial pressure in disease conditions: A prospective cohort study (Beijing iCOP study)

BMC Neurology ◽  
2012 ◽  
Vol 12 (1) ◽  
Author(s):  
Zhen Li ◽  
Yingxin Yang ◽  
Yan Lu ◽  
Dachuan Liu ◽  
Erhe Xu ◽  
...  
Keyword(s):  
Cohort Study ◽  
Intraocular Pressure ◽  
Intracranial Pressure ◽  
Prospective Cohort Study ◽  
Prospective Cohort

Retinal Vein Pulsation is in Phase with Intracranial Pressure and not Intraocular Pressure

2012 ◽  
Vol 53 (10) ◽  
pp. 6045 ◽  
Author(s):  
Jost B. Jonas ◽  
Ningli Wang ◽  
Diya Yang
Keyword(s):  
Intraocular Pressure ◽  
Intracranial Pressure

scholarly journals Accuracy of Noninvasive Intraocular Pressure or Optic Nerve Sheath Diameter Measurements for Predicting Elevated Intracranial Pressure in Cryptococcal Meningitis

2014 ◽  
Vol 1 (3) ◽  
Author(s):  
Henry W. Nabeta ◽  
Nathan C. Bahr ◽  
Joshua Rhein ◽  
Nicholas Fossland ◽  
Agnes N. Kiragga ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Optic Nerve ◽  
Intracranial Pressure ◽  
Cryptococcal Meningitis ◽  
Optic Nerve Sheath Diameter ◽  
Diagnostic Value ◽  
Optic Nerve Sheath ◽  
Increased Intracranial Pressure ◽  
Nerve Sheath ◽  
Immunodeficiency Virus

Abstract Background.  Cryptococcal meningitis is associated with increased intracranial pressure (ICP). Therapeutic lumbar puncture (LP) is recommended when the initial ICP is >250 mm H2O, yet the availability of manometers in Africa is limited and not always used where available. We assessed whether intraocular pressure could be a noninvasive surrogate predictor to determine when additional therapeutic LPs are necessary. Methods.  Ninety-eight human immunodeficiency virus-infected Ugandans with suspected meningitis (81% Cryptococcus) had intraocular pressure measured using a handheld tonometer (n = 78) or optic nerve sheath diameter (ONSD) measured by ultrasound (n = 81). We determined the diagnostic performance of these methods for predicting ICP vs a standard manometer. Results.  The median ICP was 225 mm H2O (interquartile range [IQR], 135–405 mm H2O). The median intraocular pressure was 28 mm Hg (IQR, 22–37 mm Hg), and median ultrasound ONSD was 5.4 mm (IQR, 4.95–6.1 mm). ICP moderately correlated with intraocular pressure (ρ = 0.45, P < .001) and with ultrasound ONSD (ρ = 0.44, P < .001). There were not discrete threshold cutoff values for either tonometry or ultrasound ONSD that provided a suitable cutoff diagnostic value to predict elevated ICP (>200 mm H2O). However, risk of elevated ICP >200 mm H2O was increased with an average intraocular pressure >28 mm Hg (relative risk [RR] = 3.03; 95% confidence interval [CI], 1.55–5.92; P < .001) or an average of ONSD >5 mm (RR = 2.39; 95% CI, 1.42–4.03; P = .003). As either intraocular pressure or ONSD increased, probability of elevated ICP increased (ie, positive predictive value increased). Conclusions.  Noninvasive intraocular pressure measurements by tonometry or ultrasound correlate with cerebrospinal fluid opening pressure, but both are a suboptimal replacement for actual ICP measurement with a manometer.

Negative-pressure hydrocephalus

1995 ◽  
Vol 83 (3) ◽  
pp. 486-490 ◽  
Author(s):  
Michael Vassilyadi ◽  
Jean-Pierre Farmer ◽  
José L. Montes
Keyword(s):  
Intracranial Pressure ◽  
Pressure Gradient ◽  
Negative Pressure ◽  
Subarachnoid Space ◽  
Ventricular Dilation ◽  
Content Type ◽  
Arnold Chiari Malformation ◽  
System A ◽  
Subarachnoid Spaces ◽  
Fine Print

✓ Two cases of children with closed myelodysplasia, Arnold-Chiari malformation, and shunted hydrocephalus who underwent spinal arachnoid cystopleural shunting are presented. Postoperatively, both patients developed craniovertebral symptomatology accompanied by radiologically documented ventricular dilation in spite of negative intracranial pressure and functional ventriculoperitoneal (VP) shunts. Both patients recovered after the cystopleural shunts were revised to increase the resistance to flow within the system. The authors believe that some communication between the arachnoid cyst and the subarachnoid space existed in both cases and that the negative pleural pressure was transmitted preferentially to the spinal and cerebral convexity subarachnoid spaces with relative sparing of the ventricular system. A transmantle pressure gradient was thereby established, leading to ventricular dilation. The authors further suggest that a craniospinal gradient was possibly established as well, leading to craniovertebral symptomatology in the patients. Return of flow in the VP shunts was obtained by correcting this iatrogenic transmantle pressure gradient.

The Influence of Translaminar Pressure Gradient and Intracranial Pressure in Glaucoma

2019 ◽  
pp. 1
Author(s):  
David Andrew Price ◽  
Alon Harris ◽  
Brent Siesky ◽  
Sunu Mathew
Keyword(s):  
Intracranial Pressure ◽  
Pressure Gradient

scholarly journals The Relationships Among Transverse Sinus Stenosis Measured by CT Venography, Venous Trans-stenotic Pressure Gradient and Intracranial Pressure in Patients With Unilateral Venous Pulsatile Tinnitus

2021 ◽  
Vol 15 ◽  
Author(s):  
Xiaoyu Qiu ◽  
Pengfei Zhao ◽  
Xiaoshuai Li ◽  
Heyu Ding ◽  
Han Lv ◽  
...  
Keyword(s):  
Intracranial Pressure ◽  
Pressure Gradient ◽  
Characteristic Curve ◽  
Transverse Sinus ◽  
Optimal Threshold ◽  
Pulsatile Tinnitus ◽  
Cross Sectional ◽  
Predictive Values ◽  
Non Invasive ◽  
Sinus Stenosis

ObjectivesTo assess a non-invasive means of predicting a venous trans-stenotic pressure gradient (TPG) and intracranial pressure (ICP) as opposed to invasive examinations in unilateral venous pulsatile tinnitus (PT) patients.MethodsThirty patients with unilateral venous PT who presented symptomatic-sided transverse sinus stenosis (TSS) on computed tomography venography (CTV), ipsilateral TPG measured by digital subtraction angiography (DSA) and cerebrospinal fluid (CSF) pressure measured by lumbar puncture were included. The ratio of TSS was calculated by dividing the cross-sectional areas of the maximal stenosed transverse sinus by that of the adjacent normal transverse sinus on CTV. The correlations among and predictive values of TSS, TPG, and ICP were analyzed.ResultsIn patients with unilateral venous PT, the symptomatic-sided and average bilateral TSS values were 78 ± 11 and 77 ± 9%; ICP, 230.50 ± 55.75 mmH2O; and the TPG, 9.51 ± 5.76 mmHg. The symptomatic-sided TSS was linearly and positively correlated with TPG (R2 = 0.400), and the symptomatic-sided and bilateral average TSS both showed weak correlations with ICP (R2 = 0.288, R′2 = 0.156). When the degree of TSS increased by 10%, the TPG and ICP increased by approximately 3.3 mmHg and 25.8 mmH2O, respectively. The receiver operating characteristic curve showed the optimal threshold of ipsilateral TSS for a positive TPG was 0.75, while TSS had no significant predictive value for ICP (p > 0.05). TPG and ICP also exhibited a linear positive correlation (R2 = 0.552). When ICP increased by 10 mmH2O, the TPG increased by approximately 0.77 mmHg, and the optimal threshold of ICP for a positive TPG was 227.5.ConclusionTSS, TPG, and ICP are interrelated. TSS measured by CTV can predict TPG in patients with unilateral venous PT.

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