scholarly journals Human parainfluenza virus evolution during lung infection of immunocompromised humans promotes viral persistence

2021 ◽  
Author(s):  
Alexander L. Greninger ◽  
Ksenia Rybkina ◽  
Michelle J. Lin ◽  
Jennifer Drew-Bear ◽  
Tara C. Marcink ◽  
...  
Keyword(s):  
Viral Persistence ◽  
Lung Infection ◽  
Virus Evolution ◽  
Parainfluenza Virus ◽  
Human Parainfluenza Virus

Neonatal-Onset Familial Mediterranean Fever in an Infant with Human Parainfluenza Virus-4 Infection

Neonatology ◽  
2021 ◽  
pp. 1-5
Author(s):  
Alexandre Michev ◽  
Alessandro Borghesi ◽  
Caterina Tretti ◽  
Maddalena Martella ◽  
Amelia Di Comite ◽  
...  
Keyword(s):  
Familial Mediterranean Fever ◽  
Parainfluenza Virus ◽  
Compound Heterozygous ◽  
Inborn Errors ◽  
Immunological Responses ◽  
Inflammatory Conditions ◽  
Neonatal Onset ◽  
Mediterranean Fever ◽  
Compound Heterozygous Variants ◽  
Human Parainfluenza Virus

Unusual, severe infections or inflammatory episodes in newborns and infants are largely unexplained and often attributed to immature immune responses. Inborn errors of immunity (IEI) are increasingly recognized as the etiology of life-threatening inflammatory and infectious diseases in infancy. We describe a patient with a unique neonatal-onset Familial Mediterranean Fever (FMF) due to compound heterozygous variants in <i>MEFV</i>, presenting as pleuritis following human parainfluenza virus-4 infection. Diagnostic challenges of FMF in infancy include the interpretation of the attacks as infectious episodes. Newborns and infants with acute, recurrent, or chronic, unusually severe infectious or inflammatory conditions should be screened for IEI, including both disorders with defective immunological responses and autoinflammatory disorders.

scholarly journals Epidemiological Investigation and Seroprevalence of Human Parainfluenza Virus in Mie Prefecture in Japan during 2009^|^ndash;2013

2014 ◽  
Vol 67 (6) ◽  
pp. 506-508 ◽  
Author(s):  
Takuya Yano ◽  
Miwa Fukuta ◽  
Chie Maeda ◽  
Shigehiro Akachi ◽  
Yukari Matsuno ◽  
...  
Keyword(s):  
Parainfluenza Virus ◽  
Epidemiological Investigation ◽  
Human Parainfluenza Virus
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