Is poor insight in psychotic disorders associated with poor performance on the Wisconsin Card Sorting Test? [published erratum appears in Am J Psychiatry 1996 Feb;153(2):270]

1995 ◽  
Vol 152 (9) ◽  
pp. 1380-1382 ◽  
Keyword(s):  
Psychotic Disorders ◽  
Poor Performance ◽  
Wisconsin Card Sorting Test ◽  
Card Sorting ◽  
Wisconsin Card Sorting ◽  
Sorting Test

Cognitive Inflexibility and Pre-frontal Dysfunction in Schizophrenia and Mania

1990 ◽  
Vol 157 (1) ◽  
pp. 50-54 ◽  
Author(s):  
Rodney Morice
Keyword(s):  
Cognitive Assessment ◽  
Poor Performance ◽  
Wisconsin Card Sorting Test ◽  
Control Group ◽  
Card Sorting ◽  
Frontal Dysfunction ◽  
Cognitive Inflexibility ◽  
Wisconsin Card Sorting ◽  
Sorting Test ◽  
And Control

The ability to shift cognitive set, which is probably subserved, at least in part, by the pre-frontal cortex, was determined for schizophrenic, bipolar (manic) and control subjects, using the Wisconsin Card Sorting Test (WCST). The schizophrenic and manic subjects both demonstrated poor performance on the WCST, suggesting that cognitive inflexibility and/or pre-frontal dysfunction, is not specific to schizophrenia (although laterality differences could exist). Moderate levels of poor performance in the non-psychiatric control group suggest the need for a review of the cut-off figures in the WCST currently used for predicting ‘brain damage’ and ‘focal frontal involvement‘, especially given the trend for the increasing use of cognitive assessment and rehabilitation in the major psychoses.

Dopaminergic Genes Polymorphisms and Prefrontal Cortex Efficiency Among Obese People - Whether Gender is a Differentiating Factor?

2019 ◽  
Vol 19 (6) ◽  
pp. 405-418
Author(s):  
Maciej Bieliński ◽  
Natalia Lesiewska ◽  
Roman Junik ◽  
Anna Kamińska ◽  
Andrzej Tretyn ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Executive Functions ◽  
Tandem Repeats ◽  
Wisconsin Card Sorting Test ◽  
Variable Number ◽  
Card Sorting ◽  
Obese People ◽  
Perseverative Errors ◽  
Wisconsin Card Sorting ◽  
Sorting Test

Background:Obesity is a chronic condition associated with poorer cognitive functioning. Wisconsin Card Sorting Test (WCST) is a useful tool for evaluating executive functions. In this study, we assessed the association between dopaminergic gene polymorphisms: DAT1 (SLC6A3), COMTVal158Met, DRD4 (48-bp variable number of tandem repeats - VNTR) and WCST parameters to investigate the functions of the frontal lobes in obese individuals.Objective:To find the significant correlations between polymorphisms of DAT1, COMTVal158Met, DRD4 and executive functions in obese subjects.Methods:The analysis of the frequency of individual alleles was performed in 248 obese patients (179 women, 69 men). Evaluation of the prefrontal cortex function (operating memory and executive functions) was measured with the Wisconsin Card Sorting Test (WCST). Separate analyzes were performed in age subgroups to determine different activities and regulation of genes in younger and older participants.Results:Scores of WCST parameters were different in the subgroups of women and men and in the age subgroups. Regarding the COMT gene, patients with A/A and G/A polymorphisms showed significantly better WCST results in WCST_P, WCST_CC and WCST_1st. Regarding DAT1 men with L/L and L/S made less non-perseverative errors, which was statistically significant. In DRD4, significantly better WCST_1st results were found only in older women with S allele.Conclusion:Obtained results indicate the involvement of dopaminergic transmission in the regulation of prefrontal cortex function. Data analysis indicates that prefrontal cortex function may ensue, from different elements such as genetic factors, metabolic aspects of obesity, and hormonal activity (estrogen).

Fast Neural Dynamics of Proactive Cognitive Control in a Task-Switching Analogue of the Wisconsin Card Sorting Test

2017 ◽  
Vol 31 (3) ◽  
pp. 407-418 ◽  
Author(s):  
Gema Díaz-Blancat ◽  
Juan García-Prieto ◽  
Fernando Maestú ◽  
Francisco Barceló
Keyword(s):  
Cognitive Control ◽  
Task Switching ◽  
Wisconsin Card Sorting Test ◽  
Neural Dynamics ◽  
Card Sorting ◽  
Wisconsin Card Sorting ◽  
Sorting Test

No deficit in Wisconsin Card Sorting Test performance of schizophrenic patients' first-degree relatives

1997 ◽  
Vol 26 (2-3) ◽  
pp. 147-151 ◽  
Author(s):  
P Stratta ◽  
E Daneluzzo ◽  
P Mattei ◽  
M Bustini ◽  
M Casacchia ◽  
...  
Keyword(s):  
Test Performance ◽  
Wisconsin Card Sorting Test ◽  
Card Sorting ◽  
First Degree Relatives ◽  
Schizophrenic Patients ◽  
Wisconsin Card Sorting ◽  
Sorting Test
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