Acoustic Rhinometry in the Study of the Acute Nasal Allergic Response

1996 ◽  
Vol 105 (10) ◽  
pp. 811-818 ◽  
Author(s):  
Burton Zweiman ◽  
Richard Doty ◽  
Andrew P. Lane ◽  
Donald C. Lanza ◽  
Hun-Jun Dhong ◽  
...  
Keyword(s):  
Nasal Cavity ◽  
Objective Assessment ◽  
Allergen Challenge ◽  
Olfactory Function ◽  
Acoustic Rhinometry ◽  
Allergic Response ◽  
Nasal Airway ◽  
Nasal Patency ◽  
Airway Caliber ◽  
Nasal Allergen Challenge

Acoustic rhinometry is a recently developed method for the objective assessment of nasal patency. In this study, acoustic rhinometry was used to measure changes in nasal cavity dimensions in the immediate response to nasal allergen challenge in eight pollen-sensitive subjects. Acoustic rhinometric changes were compared with subjective symptoms, as well as histamine in nasal secretions, cytology of nasal mucosal scrapings, and changes in olfactory function. A significantly greater decrease in nasal airway caliber occurred following allergen challenge as compared to buffer diluent challenge in the same individuals (70% ± 1% versus 22% ± 5%). During an allergic response, a strong correlation was found between the minimum cross-sectional area and the volume of the nasal cavity measured by acoustic rhinometry (r = .9). However, no correlation was observed between nasal airway caliber and concomitant subjective congestion reported by the subjects. Amodest decrease in olfactory function was seenfollowing allergen challenge (3.1 ± 1.4 fewer odors identified correctly out of 20; p = .08). However, the alterations of olfactory function did not correlate with changes in nasal patency. The results presented in this study demonstrate that acoustic rhinometry has great potential as a reproducible method for the objective assessment of nasal obstruction occurring in nasal allergen challenge studies.

Reproducibility of Acoustic Rhinometry in the Investigation of Occupational Rhinitis

2007 ◽  
Vol 21 (4) ◽  
pp. 474-477 ◽  
Author(s):  
Roberto Castano ◽  
Gilles Thériault ◽  
Denyse Gautrin ◽  
Heberto Ghezzo ◽  
Carole Trudeau ◽  
...  
Keyword(s):  
Objective Assessment ◽  
Intraclass Correlation ◽  
Correlation Coefficients ◽  
Acoustic Rhinometry ◽  
Nasal Patency ◽  
Cross Sectional ◽  
Occupational Rhinitis ◽  
Intraclass Correlation Coefficients ◽  
Objective Monitoring ◽  
Coefficients Of Variation

Background To diagnose occupational rhinitis, it is mandatory to conduct an objective assessment of changes in nasal patency during specific inhalation challenge (SIC). The reproducibility of acoustic rhinometry measurements in the setting of occupational challenges has never been examined. This study assessed the reproducibility of acoustic rhinometry during SIC investigation of occupational rhinitis. Methods Twenty-four subjects underwent acoustic rhinometry measurements during SIC investigation of occupational rhinitis. Subjects attended 3–6 days of SIC within a week by means of a realistic or closed-circuit apparatus methodology Results All of the within-day intraclass correlation coefficients (ICCs) for nasal volume (2–5 cm) and minimum cross-sectional area (MCA) based on a different number of measurements (2–7) were above 0.85; all of the coefficients of variation (CVs) for the same parameters were low (below 10%). The between-day CVs based on different numbers of SIC sessions ranged from 8.0 to 8.8% and from 6.8 to 8.8% for nasal volume and MCA, respectively. The between-day ICCs ranged from 0.80 to 0.88 and from 0.83 to 0.94 for nasal volume and MCA, respectively. Conclusion Acoustic rhinometry showed good within- and between-day reproducibility and can be recommended for the objective monitoring of nasal patency during SIC investigating occupational rhinitis.

Objective Assessment of the Breathe-Right Device during Exercise in Adult Males

1997 ◽  
Vol 11 (5) ◽  
pp. 393-398 ◽  
Author(s):  
Louis G. Portugal ◽  
Rajeev H. Mehta ◽  
Bonnie E. Smith ◽  
Jaishiri B. Sabnani ◽  
Matthew J. Matava
Keyword(s):  
African American ◽  
Objective Assessment ◽  
Acoustic Rhinometry ◽  
Nasal Airway ◽  
Nasal Resistance ◽  
Adult Males ◽  
Nasal Breathing ◽  
Cross Sectional ◽  
American Group ◽  
Paradoxical Worsening

In order to improve nasal breathing during competition, many athletes recently have been wearing a spring-loaded, external nasal dilator referred to as the Breathe-Right device (BRD). Although there are many subjective claims that this device improves breathing during exercise, there are currently no controlled studies documenting its efficacy. To determine objectively whether the device improves the nasal airway, 20 subjects (10 Caucasian and 10 African-American) were studied during rest and after 15 minutes of exercise using anterior rhinomanometry and acoustic rhinometry to measure changes in airway resistance and minimal cross-sectional area, respectively. We found that the BRD exerts its main effect in the region of the nasal valve improving the airway an overall 21% in our group of subjects. This anatomic improvement in nasal airway resulted in an overall 27% reduction in nasal resistance in the Caucasian group. However, in the African-American group, a wider range of resistance changes was observed with application of the BRD with significant improvement in nasal resistance in some subjects but paradoxical worsening in others. In the African-American group as a whole, no significant change in nasal resistance occured with application of the BRD. These measured differences are likely due to variations in nasal anatomy that exist not only between races but also between individuals within a given race. In addition, this study confirms the well known decongestant effects of exercise providing anatomic data with acoustic rhinometry not previously documented in the literature. Overall improvement in nasal airway seen with application of the BRD occured independent of these exercise-related decongestant effects.

Comparison of diagnostic accuracy of acoustic rhinometry and symptoms score for nasal allergen challenge monitoring

Allergy ◽  
2020 ◽  
Vol 76 (1) ◽  
pp. 371-375 ◽  
Author(s):  
Ibon Eguiluz‐Gracia ◽  
Almudena Testera‐Montes ◽  
Maria Salas ◽  
Natalia Perez‐Sanchez ◽  
Adriana Ariza ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Allergen Challenge ◽  
Acoustic Rhinometry ◽  
Nasal Allergen Challenge

Determinants and Evaluation of Nasal Airflow Perception

2017 ◽  
Vol 33 (04) ◽  
pp. 372-377 ◽  
Author(s):  
Kevin Hur ◽  
Kai Zhao ◽  
Donald Leopold ◽  
Bozena Wrobel ◽  
Jasper Shen
Keyword(s):  
Treatment Outcome ◽  
Airway Obstruction ◽  
Airway Resistance ◽  
Dynamic Change ◽  
Acoustic Rhinometry ◽  
Nasal Airway ◽  
Nasal Airflow ◽  
Nasal Patency ◽  
Airway Patency

AbstractThe sensation of nasal airflow, or nasal airway patency, is an important consideration in the treatment outcome of nasal airway obstruction. Clinicians striving to optimize the nasal passageway have relied on techniques aimed at decreasing peak airway resistance across nasal valves. Nonetheless, the evaluation of the nasal airway is multifaceted, and the objective determinants of subjective nasal patency remain incompletely elucidated. While rhinomanometry, peak nasal inspiratory airflow, and acoustic rhinometry have traditionally been used in research to focus on resistance as a measure of patency, an emerging body of evidence suggests that subjective nasal patency is more significantly correlated to the dynamic change of nasal mucosal temperature. The objective of this review is to provide the technical background on nasal airflow perception and intranasal trigeminal function as crucial to those performing functional and aesthetic rhinosurgery.

scholarly journals Nasal airway interference: considerations for evaluation.

1988 ◽  
Vol 14 (1) ◽  
pp. 11-21
Author(s):  
John Riski ◽  
Keyword(s):  
Nasal Cavity ◽  
Nasal Airway ◽  
Response Patterns ◽  
Nasal Patency ◽  
Special Issue ◽  
Adaptive Process ◽  
Respiratory Tree ◽  
Physiological Demands ◽  
Broad Subject

Introduction: Respiration for speech and non-speech activities is an ongoing, adaptive process. The adaptations involved may relate to anatomical factors in the respiratory tree, or physiological demands in the environment. When the nasal cavity is not adequately patent, adjustments in oral and pharyngeal posture must take place in order to allow respiration to proceed effectively. In some instances resting oral postures may be influenced and habit response patterns may be developed. These adjustments of oral posture are the broad subject of this journal special issue. More specific to the article, the discussion is of those factors which influence nasal patency and the techniques available for measuring the degree of nasal patency. [excerpt]

Nasal airway changes assessed by acoustic rhinometry and mediator release during immediate and late reactions to allergen challenge

1997 ◽  
Vol 100 (5) ◽  
pp. 624-631 ◽  
Author(s):  
Burton Zweiman ◽  
John Getsy ◽  
Mark Kalenian ◽  
Andrew Lane ◽  
Lawrence B. Schwartz ◽  
...  
Keyword(s):  
Allergen Challenge ◽  
Acoustic Rhinometry ◽  
Mediator Release ◽  
Nasal Airway

The Effect of Cetirizine on Nasal Allergic Response

1995 ◽  
Vol 9 (6) ◽  
pp. 361-366 ◽  
Author(s):  
P. Small ◽  
Doreen Barrett
Keyword(s):  
Late Phase ◽  
Eosinophil Cationic Protein ◽  
Allergen Challenge ◽  
Early Response ◽  
Significant Rise ◽  
Phase Changes ◽  
Allergic Response ◽  
Response Threshold ◽  
Cationic Protein ◽  
Nasal Allergen Challenge

The effect of cetirizine on both early and late nasal allergic response was assessed in 15 ragweed sensitive patients. All patients were challenged before treatment and after 7 days of cetirizine 10 mg qd. Clinical assessments and measurements of mediators were performed at baseline, after positive challenge, 1 and 2 hours later, and repeated 7 and 8 hours later. There was a significant change (P < 0.0001) in the early response threshold to ragweed challenges after cetirizine. There were early phase elevations of prostaglandin D2, leukotriene C4, and eosinophil cationic protein both pre and post-treatment. Late phase changes were difficult to detect, but a statistically significant rise of both prostaglandin D2 and histamine was diminished after cetirizine treatment. Cetirizine clinically inhibited the early response to nasal allergen challenge, but early mediators were not affected. An effect on the late phase could not be clearly demonstrated.

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