scholarly journals Superficial Deposit of Cholesterin in Corneal Scar

1922 ◽  
Vol 15 (Sect_Ophthalmol) ◽  
pp. 23-23
Author(s):  
R. Affleck Greeves
2012 ◽  
Vol 4 (1) ◽  
Author(s):  
Márton Veress ◽  
István Németh ◽  
Roland Schläffer

AbstractThe effects of the intensive rainfall episodes in the years 2009 and 2010 in the Kőszeg Mountains were investigated. Channel profiles were constructed at various times during these periods, which were used to describe the channel changes. We measured the length of the incised and filled sections on multiple occasions. We could establish the degree and the direction of the changes using this data. The sediment veneer that developed in the area of Kőszeg town was mapped and its conditions of development were examined. The erosion and accumulation landforms developed during these years were classified and described. These forms are the following: rills, gullies, alluvial fans and sediment veneer. We distinguished and characterised those which had previously formed, but they were changed or increased (the channels). We established the conditions under which the sediment veneer can develop, furthermore those conditions which can increase the chance of the formation of this landform. These conditions are the following: the high density of roads in the catchment areas of valleys leading to settlements, the great thickness of superficial deposit, and the steep slope of the surface of the catchment area. We created theoretical classification of the morphological environment where the development of sediment veneer may happen and identified settlements with structures which promote or prevent the development of the sediment veneer. We determined the probability of the development of the sediment veneer at some settlements in Kőszeg, and suggestions have been given to decrease the chance of the development of this sediment veneer.


2013 ◽  
Vol 5 (2) ◽  
pp. 207-214 ◽  
Author(s):  
Leena Bajracharya ◽  
R Gurung ◽  
EH DeMarchis ◽  
M Oliva ◽  
S Ruit ◽  
...  

Introduction: Corneal disease, especially infective keratitis, is one of the major causes of visual impairment and blindness in developing countries. Objective: To find out the current indications for keratoplasty, how these indications have changed over time as well as how they are different from those in other parts of the world. Materials and methods: A retrospective study of a case series of 645 keratoplasty surgeries (589 patients) was conducted at the Tilganga Institute of Ophthalmology from January 2005 to December 2010. Outcome measures: The cases were evaluated in terms of demographic parameters, preoperative diagnosis and the type of surgery performed. Results: The most common indication for surgery was active infectious keratitis (264 eyes, 40.9 %), followed by corneal opacity (173 eyes, 26.8 %), regraft (73 eyes, 11.2 %), bullous keratopathy (58 eyes, 9.0 %), keratoconus (45 eyes, 7.0 %) and corneal dystrophy (11 eyes, 1.7 %). The mean recipient age was 41.7 ± 19.9 years with over a half of the patients between 15 to 49 years of age. More men (64.1 %) underwent keratoplasty than women (35.8 %). 59.8 % of the eyes with infectious keratitis had a perforated corneal ulcer. 49.7 % of corneal opacities were due to previous infectious keratitis. 72 % of regrafts were for endothelial failure of various causes. In older patients (> 50 years), bullous keratopathy was an important indication, after infectious keratitis. Keratoconus and corneal scar were major causes of keratoplasty in children of 14 years or less. Four percent of the patients had keratoplasty in both the eyes. 17.1 % of the patients who had one eye operated on had a blind fellow eye with a vision of less than 3/60. Conclusion: Currently, keratitis, either active or healed, is the major indication for keratoplasty, suggesting that improved primary eye health care is necessary to decrease the prevalence of corneal blindness. Nepal J Ophthalmol 2013; 5(10): 207-214 DOI: http://dx.doi.org/10.3126/nepjoph.v5i2.8730


1994 ◽  
Vol 67 (4) ◽  
pp. 1743-1748 ◽  
Author(s):  
I.M. Rawe ◽  
K.M. Meek ◽  
D.W. Leonard ◽  
T. Takahashi ◽  
C. Cintron

2017 ◽  
Vol 233 (5) ◽  
pp. 3817-3830 ◽  
Author(s):  
Shikha Chawla ◽  
Sourabh Ghosh

Author(s):  
Sakar Abdulkarim Nidhamalddin

To compare the effects of using motorized diamond burr polisher in pterygium excision versus manual polishing of the corneoscleral bed in reducing the recurrent rate. A prospective, comparative and interventional study of 90 consecutive patients with different grads of primary pterygium, who underwent pterygium excision at Shahid Aso teaching eye hospital in Sulaimani city, between August 2018 till September 2019, which was performed by single surgeon. In group A (45) eyes polishing of the corneoscleral bed done using motorized diamond polishing burr, and in group B (45) eyes using manual crescent blade for polishing. Recurrent rate was evaluated after about (8±2) months postoperatively. Ethical consideration of the risks and the benefits of the procedure was observed for each individual patient. A 90 patients with the mean age of group A (48.84±12.7) years and group B (49.67±12.3) years, complained of different grads of primary pterygium, group A had 31(68.9%) male and 14(31.1%) female, while group B had 22(48.9%) male and 23(51.1%) female. Each individual factors like age, gender, visual acuity, BCVA pre and postoperatively, IOP measurement, dryness of the eye and risk factors like smoking and UV exposure affecting the recurrence were assessed. In both groups the main indication for surgery was sign of irritation. The mean surgical time was calculated and the difference between two groups were significant. After follow-up of average six months the outcomes and recurrent rate were checked, recurrent rate was in group A 1(2.2%) while in group B was 6(13.3%) patients. it significantly decreased. Corneal scar happens in only 1(2.2%) case of group A while in 11(24.4%) cases in group B, Corneal scar was statistically significant. In both groups the change of BCVA was significant but the visual change was more significant in group A in compare to group B. Motorized diamond burr is a safe instrument for polishing the cornea during pterygium excision, it is easy to handle, low price, need lesser operative time, its effect on recurrence postoperatively is significant and beside it leaves lesser corneal scar and early visual recovery postoperatively.   


2019 ◽  
Author(s):  
Yue Zhou ◽  
Yuqing Chen ◽  
Suiyue Wang ◽  
Fangyuan Qin ◽  
Wang liya

Abstract Background Fungal Keratitis (FK) is an infective keratopathy with extremely high blindness rate. The damaging effect of this disease is not only the destruction of corneal tissue during fungal infection, but also the cornea scar formed during the healing period after infection control, which can also seriously affect a patient's vision. The purpose of the study was to observe the effect of umbilical cord mesenchymal stem cells (uMSCs) on corneal scar formation in FK. Methods The FK mouse model was made according to a previously reported method. Natamycin eye drops were used for antifungal treatment 24 hours after modeling. There are four groups involved in the study, including control group, FK group, vehicleinj FK group and uMSCsinj FK group. Mice in uMSCsinj FK group received repeated subconjunctival injections of uMSCs for 3 times at the 1d, 4d and 7d after FK modeling. At 14d, 21d and 28d after trauma, clinical observation, histological examination, second harmonic generation and molecular assays were performed. Results The uMSCs topical administration reduced corneal scar formation area and corneal opacity, accompanying with decreased corneal thickness and inflammatory cell infiltration, following down-regulated fibrotic-related factors α-SMA, TGFβ1, CTGF, and COLI and finally inhibited phosphorylation of TGFβ1/Smad2 signaling pathway during FK corneal fibrosis. Conclusion The results confirmed that uMSCs can improve corneal opacity during the scar formation stage of FK, and exert anti-inflammatory and anti-fibrotic effects..


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