scholarly journals Three Synchronous Head and Neck Cancers: A Multidisciplinary and Surgical Challenge

2021 ◽  
pp. 014556132110079
Author(s):  
Fabio Bertone ◽  
Emanuele Robiolio ◽  
Luca Robiolio ◽  
Daniele Liscia ◽  
Carmine F. Gervasio
Keyword(s):  
Head And Neck ◽  
Narrow Band Imaging ◽  
Free Edge ◽  
Endoscopic Examination ◽  
Head And Neck Cancers ◽  
Second Primary ◽  
Primary Cancer ◽  
Aryepiglottic Fold ◽  
First Case ◽  
Laser Excision

Second primary cancer (SPC) is a term used to describe a new primary cancer occurring in patients who had formerly been diagnosed with tumor. Even though SPCs appear to be related to primary cancers, they are actually entities that have arisen independently and not as a result of recurrence. This report is of the first case in literature of a patient hospitalized for the surgical treatment of 3 synchronous Head and Neck Cancers. A 66-year-old male was admitted to our hospital (Ospedale Degli Infermi—Biella, Italy) complaining about pharyngodynia. Three different lesions were identified through endoscopic examination and narrow band imaging: the first one on left tonsil, the second one on epiglottis, and the third one on right aryepiglottic fold. The case was subject to a multidisciplinary team analysis due to its complexity, then the surgery consisted in (1) CO2 laser left tonsillectomy, associated with (2) CO2 laser excision of the lesion on epiglottis free edge, and (3) CO2 laser excision of right aryepiglottic fold lesion. Synchronous tumors are among the most defiant challenges for surgeons since no international guideline specifies differentiated strategies to be adopted in patients affected by synchronous Head and Neck Cancers, therefore surgical planning must be tailored differently from patient to patient, and many unsolved questions still concern clinical treatments to be adopted.

The risk of hepatocellular carcinoma in patients with previous malignancy

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 17075-17075
Author(s):  
A. B. Siegel ◽  
R. B. McBride ◽  
H. El-Serag ◽  
D. Hershman ◽  
L. Zablotska ◽  
...  
Keyword(s):  
United States ◽  
Risk Factors ◽  
Hepatocellular Carcinoma ◽  
Head And Neck ◽  
Kaposi's Sarcoma ◽  
Kaposi’S Sarcoma ◽  
The United States ◽  
Head And Neck Cancers ◽  
Second Primary ◽  
Primary Cancer

17075 Background: Hepatocellular carcinoma (HCC) is one of the most common malignancies in the world. Its incidence has doubled over the past 20 years in the United States. Determination of the pattern of occurrence of HCC as a second primary malignancy might give clues for new risk factors for HCC, or may reveal common genetic or environmental risks. Methods: We identified patients with a diagnosis of a second primary HCC between 1973 and 2002 using the Surveillance, Epidemiology, and End-Results Program (SEER) a compilation of population-based cancer registries in the United States, to calculate the observed to expected (O/E) frequency of second primary HCC after a different primary cancer. We stratified by ethnicity, latency from the year of diagnosis of primary cancer to HCC diagnosis, and period of diagnosis of primary cancer as early (1973–1987) or late (1987–2002). Results: We reviewed 1,931,911 subjects with cancer, and identified 1,185 second primary HCC cases. Overall, a second primary HCC after any primary cancer was less frequent than expected (O/E=0.82, 95% CI=0.77–0.87). We found positive associations with head and neck cancers (oral cavity/pharynx O/E=2.1, 95% CI=1.7–2.5), Kaposi's sarcoma (O/E=3.3, 95% CI=1.2–7.1) and Hodgkin's disease (O/E=2.3, 95% CI=1.2–4.0). Negative associations were seen for breast cancer (O/E=0.7, 95% CI=0.6–0.8), colorectal cancer (O/E=0.6, 95% CI=0.6–0.8), and prostate cancer (O/E=0.7, 95%CI=0.6–0.8). Overall, lower O/E ratios were seen in whites, while in African Americans and those of other races, the O/E ratios were close to one. Latency times were relatively short for head and neck cancers and Kaposi's sarcoma (most within 12–59 months), and greater than 120 months for most cases of HCC after Hodgkin's disease. All cases of Kaposi's sarcoma were seen in the later time period. Conclusions: These results highlight possible shared risk factors of alcohol ingestion and viral exposures which may predispose to second primary HCC after other primary malignancies. Providers should maintain heightened alertness for second primary HCC in these patients, especially those with head and neck cancers and HIV. No significant financial relationships to disclose.

Risk of second primary cancer among patients with head and neck cancers: A pooled analysis of 13 cancer registries

2008 ◽  
Vol 123 (10) ◽  
pp. 2390-2396 ◽  
Author(s):  
Shu-Chun Chuang ◽  
Ghislaine Scelo ◽  
Jon M. Tonita ◽  
Sharon Tamaro ◽  
Jon G. Jonasson ◽  
...  
Keyword(s):  
Head And Neck ◽  
Cancer Registries ◽  
Pooled Analysis ◽  
Head And Neck Cancers ◽  
Second Primary ◽  
Primary Cancer ◽  
Second Primary Cancer

Narrow Band Imaging for Detecting Metachronous Superficial Oropharyngeal and Hypopharyngeal Squamous Cell Carcinomas After Chemoradiotherapy for Head and Neck Cancers

2008 ◽  
Vol 118 (10) ◽  
pp. 1787-1790 ◽  
Author(s):  
Chikatoshi Katada ◽  
Meijin Nakayama ◽  
Satoshi Tanabe ◽  
Wasaburo Koizumi ◽  
Takashi Masaki ◽  
...  
Keyword(s):  
Head And Neck ◽  
Squamous Cell ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Squamous Cell Carcinomas ◽  
Head And Neck Cancers

scholarly journals Effectiveness of planned surveillance for detecting second primary head and neck cancers after endoscopic resection of esophageal squamous cell carcinoma

2020 ◽  
Vol 50 (10) ◽  
pp. 1162-1167 ◽  
Author(s):  
Takeshi Shinozaki ◽  
Chikatoshi Katada ◽  
Kiyoto Shiga ◽  
Takahiro Asakage ◽  
Tetsuji Yokoyama ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Endoscopic Resection ◽  
Squamous Cell ◽  
Head And Neck Cancers ◽  
Transoral Surgery ◽  
Second Primary ◽  
Laryngeal Function

Abstract Background Second primary head and neck cancers after endoscopic resection of esophageal squamous cell carcinoma adversely affect patients’ outcomes and the quality of life; however, an adequate surveillance schedule remains unclear. Methods We analyzed 330 patients with early esophageal squamous cell carcinoma who underwent endoscopic resection and were registered in the multicenter cohort study to evaluate adequate surveillance for detection of second primary head and neck cancers. Gastrointestinal endoscopists examined the head and neck regions after 3–6 months of endoscopic resection for esophageal squamous cell carcinoma and subsequently every 6 months. An otolaryngologist also examined the head and neck regions at the time of endoscopic resection for esophageal squamous cell carcinoma and at 12 months intervals thereafter. Results During the median follow-up period of 49.4 months (1.3–81.2 months), 33 second primary head and neck cancers were newly detected in 20 patients (6%). The tumor site was as follows: 22 lesions in the hypopharynx, eight lesions in the oropharynx, two lesions in larynx and one lesion in the oral cavity. The 2-year cumulative incidence rate of second primary head and neck cancers was 3.7%. Among them, 17 patients with 29 lesions were treated by transoral surgery. One patient with two synchronous lesions was treated by radiotherapy. Two lesions in two patients were not detected after biopsy. All patients were cured with preserved laryngeal function. Conclusions Surveillance by gastrointestinal endoscopy every 6 months and surveillance by an otolaryngologist every 12 months could detect second primary head and neck cancers at an early stage, thereby facilitating minimally invasive treatment.

548 NARROW BAND IMAGING ENDOSCOPY VERSUS LUGOL CHROMOENDOSCOPY IN SCREENING FOR ESOPHAGEAL CANCER AMONG PATIENTS WITH HEAD AND NECK CANCERS: A RANDOMIZED TRIAL

2019 ◽  
Vol 89 (6) ◽  
pp. AB93-AB94
Author(s):  
Anna Chaber-Ciopinska ◽  
Michal F. Kaminski ◽  
Paulina Wieszczy ◽  
Andrzej Bielasik ◽  
Marek Bugajski ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Randomized Trial ◽  
Head And Neck ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Head And Neck Cancers
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