Metabolic Complications of Total Parenteral Nutrition: Effects of a Nutrition Support Service

1996 ◽  
Vol 20 (3) ◽  
pp. 206-210 ◽  
Author(s):  
Donna Chrisanderson ◽  
Douglas C. Heimburger ◽  
Sarah L. Morgan ◽  
Wilma J. Geels ◽  
Kathy L. Henry ◽  
...  
1998 ◽  
Vol 13 (3) ◽  
pp. 123-128 ◽  
Author(s):  
Jay J. Mamel ◽  
Margaret Kuznicki ◽  
Margaret Carter ◽  
Deborah Witt ◽  
Jeffery M. Barrett

2020 ◽  
Vol 8 ◽  
pp. 205031212093822
Author(s):  
Jie Zheng ◽  
Ying-Yi Chen ◽  
Chun-Ying Zhang ◽  
Wen-Qian Zhang ◽  
Zhi-Yong Rao

Background: Chylothorax is caused by thoracic lymphatic system injuries that leads to the lymph extravasating into the thoracic cavity. There are few reports comparing the therapeutic effects of enteral nutrition with medium-chain triglyceride and total parenteral nutrition, and the results are inconsistent. Our study aimed to research the optimum nutrition support method for chylothorax. Study design: We retrospectively reviewed 35 chylothorax patients after heart and chest surgery from 2014 to 2018, at West China Hospital of Sichuan University, among them there were 27 post-heart surgery patients. We analyzed the therapeutic effects and costs of enteral nutrition with medium-chain triglyceride (E group) and total parenteral nutrition (T group) for chylothorax. Results: The results were similar in patients with all surgeries and patients with only post heart surgery. The total cost during hospitalization in E group was higher than T group ( P < 0.01), whereas the nutrition support cost was lower ( P < 0.001). The length of hospital stay was longer in E group than T group ( P > 0.05). Time from admission to surgery was shorter and from surgery to chylothorax diagnosis was longer in E group compared with T group. Time to resolution and removal of drainage was shorter in E group than T group but the differences were not significant. Conclusion: The therapeutic effects in enteral nutrition with medium-chain triglyceride and total parenteral nutrition had no obvious differences. Moreover, enteral nutrition with medium-chain triglyceride is safer and more economical. Therefore, we suggest that enteral nutrition with medium-chain triglyceride could be the first choice to treat postoperative chylothorax when the gastrointestinal tract function is allowed, and this result could be considered for postoperative chylous ascites.


2015 ◽  
Vol 108 (12) ◽  
pp. 748-753 ◽  
Author(s):  
Mario H. Mueller ◽  
Katherine Vandenbussche ◽  
Maria Pelliccia ◽  
Myles Smith ◽  
Paul Karanicolas ◽  
...  

2017 ◽  
Vol 312 (3) ◽  
pp. G246-G256 ◽  
Author(s):  
Joseph F. Pierre

Parenteral nutrition (PN) is a lifesaving therapy that provides intravenous nutrition support to patients who cannot, or should not, feed via the gastrointestinal (GI) tract. Unfortunately, PN also carries certain risks related to infection and metabolic complications compared with enteral nutrition. In this review, an overview of PN and GI immune and microbiome changes is provided. PN impacts the gut-associated lymphoid tissue functions, especially adaptive immune cells, changes the intestinal epithelium and chemical secretions, and significantly alters the intestinal microbiome. Collectively, these changes functionally result in increased susceptibility to infectious and injurious challenge. Since PN remains necessary in large numbers of patients, the search to improve outcomes by stimulating GI immune function during PN remains of interest. This review closes by describing recent advances in using enteric nervous system neuropeptides or microbially derived products during PN, which may improve GI parameters by maintaining immunity and physiology.


Nutrition ◽  
1996 ◽  
Vol 12 (7-8) ◽  
pp. 575
Author(s):  
T. Titchen ◽  
G. Curwood ◽  
A. O'Callaghan ◽  
H. Anthony ◽  
A. Mora ◽  
...  

2006 ◽  
Vol 20 (8) ◽  
pp. 527-530 ◽  
Author(s):  
Harminder Singh ◽  
Donald R Duerksen

OBJECTIVE: Nutrition education is a required part of gastrointestinal training programs. The involvement of gastroenterologists in clinical nutrition once their training has been completed is unknown. The aim of the present study was to determine the practice pattern of gastroenterologists in clinical nutrition and their perceived adequacy of nutrition training during their gastroenterology (GI) fellowship.METHODS: The Canadian Association of Gastroenterology mailed a survey to all of its 463 Canadian clinician members and 88 trainee members. Components of the survey included knowledge of nutritional assessment and total parenteral nutrition, involvement in a nutrition support service, physician involvement in nutritional assessment and nutrition support teams, obesity management, insertion of gastrostomy (G) tubes and management of tube-related complications, and adequacy of training in clinical nutrition.RESULTS: Sixty per cent (n=279) of the Canadian Association of Gastroenterology clinicians and 38% (n=33) of the fellows responded. Of the clinicians, 80% were practicing adult gastroenterologists with the following demographics: those practicing full time in academic centres (42%), community practice (45%), completed training in the last 10 years (32%) and those that completed training in the United States (14%). Although only 6% had a primary focus of nutrition in their GI practices, 65% were involved in nutrition support (including total parenteral nutrition), 74% placed G tubes and 68% managed at least one of the major complications of G tube insertion. Respondents felt a gastroenterologist should be the physician’s consultant on nutrition support services (89%). Areas of potential inadequate training included nutritional assessment, indications for nutrition support, management of obesity and management of G tube-related complications. The majority of clinicians (67%) and trainees (73%) felt that nutrition training in their GI fellowship was underemphasized.CONCLUSIONS: The majority of Canadian gastroenterologists are involved in nutrition support. However, this survey demonstrated that nutritional training is underemphasized in most training programs. It is important for GI fellowship programs to develop standardized nutrition training that prepares trainees for their practice.


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