Acinic Cell Carcinoma of the Oral Cavity

1982 ◽  
Vol 90 (6) ◽  
pp. 696-699 ◽  
Author(s):  
William M. Keane ◽  
James C. Denneny Iii ◽  
Joseph P. Atkins ◽  
Francis McBrearty

A rare case of acinic cell carcinoma of minor salivary gland origin within the oral cavity is reported in a 62-year-old woman. These tumors most commonly arise in the parotid gland and follow an insidious course requiring long-term follow-up. The gross and histologic features of the patient's tumor include pseudoencapsulation, mixed solid and acinar architecture, microcyst formation, and the presence of conspicuous diastase-fast and PAS-positive cytoplasmic granules, characteristic of lesions that have been called acinic cell carcinoma by a variety of authors. Surgical excision is the treatment of choice. However, following an incisional biopsy, the patient refused further surgical treatment and has remained clinically disease-free three years postoperatively.

2007 ◽  
Vol 95 (4) ◽  
pp. 281-285 ◽  
Author(s):  
Mallika Tewari ◽  
Pramod Rai ◽  
Gautam Bir Singh ◽  
Mohan Kumar ◽  
Hari S. Shukla

2011 ◽  
Vol 1 (3) ◽  
pp. 58
Author(s):  
Rana Sherwani ◽  
Kafil Akhtar ◽  
Murad Ahmad ◽  
Abrar Hasan

A rare case of acinic cell carcinoma of minor salivary gland with cervical lymph node metastasis in a 50-year-old man is reported and the literature regarding this type of tumor is reviewed. These tumors arise from either an intercalated duct stem cell or the reserve cell of the salivary gland terminal tubule but not from both simultaneously. Rarely these neoplasms arise from more mature acinar cells. It is clear that these tumors behave ominously. The 25 year determinate survival rate is 50%, with a 20% incidence of metastasis. Surgical excision is the treatment of choice. Radiotherapy, especially neutron therapy, has a place in the treatment of this tumor but the role of chemotherapy is not exactly known at this time.


2013 ◽  
Vol 4 (1) ◽  
pp. 24-28
Author(s):  
Akshay Kudpaje ◽  
Sumit Gupta ◽  
Sudhir Naik ◽  
Rajshekar Halkud ◽  
V Prashanth ◽  
...  

ABSTRACT Background Acinic cell carcinoma (ACC) is a relatively rare and slowly growing tumor of the major salivary glands, usually arising from the parotid and rarely from the submandibular and sublingual salivary glands. ACC accounts for 3 to 4% of parotid tumors, 2 to 6% of all salivary gland tumors and 10 to 17% of all malignant salivary gland tumors. Case report A 40-year-old woman reported a slow growing mass in the oral cavity. The transoral aspiration biopsy was reported as pleomorphic adenoma arising from the minor salivary glands of the junctional zone of base of tongue. Rest of the neck examination was normal and magnetic resonance imaging (MRI) revealed the mass confined to the superficial layers of the tongue without invasion. Intervention The tumor was resected transorally with adequate margins. The tumor histology was typical of ACC with the margins free and wide on all the sides. The patient was kept on monthly follow-up where palpable nodes developed during the course of 6 months. The neck was addressed with supraomohyoid dissection and followed up without irradiation. Conclusion ACC is a low-grade malignant salivary neoplasm rarely diagnosed in minor salivary glands of the oral cavity. The overall prognosis after surgical resection depends on the extent of lesion and the adequacy of the initial resection. Hence, keeping in mind the malignant potential of the disease careful long-term follow-up is advised. How to cite this article Naik SM, Kudpaje A, Gupta S, Nanjundappa A, Halkud R, Prashanth V, Biswas S. Acinic Cell Carcinoma of the Minor Salivary Glands of the Tongue: A Case Study with Review of Literature. Int J Head and Neck Surg 2013; 4(1):24-28.


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