Our Experience on Light Reflection Rheography (LRR): A New Non-Invasive Method for Lower Limbs Venous Examination

1986 ◽  
Vol 1 (3) ◽  
pp. 231-241 ◽  
Author(s):  
Giuseppe Nuzzaci ◽  
Nicola Mangoni ◽  
Argene Patrizia Tonarelli ◽  
Eleonora Lucente ◽  
Daniele Righi ◽  
...  

By means of a light reflection rheograph (LRR 100), the authors studied 353 lower limbs: 128 with primary varices, 41 with a post-phlebitic syndrome and 81 controls. The parameters that were selected were: VRT (venous refill time) and ΔLR (as expression of the venous emptying rate). In order to assess the accuracy of LRR measurements, simultaneous recordings of both LRR and venous pressure changes in 97 limbs (58 with primary varicose disease, 21 with post-phlebitic syndrome and 18 normals) were compared with each other. The correlation rate for VRT in the two methods revealed very high agreement, (r = 0.96). A fairly good correlation also occurred between changes in venous pressure and ΔLR (r = 0.74). The reproducibility rates ranged between ± 15.9% s.d. (VRT) and ± 7.7% s.d. (ΔLR), using 100 as the average value obtained from each subject. The authors conclude that LRR appears to offer high specificity, sensitivity and reproducibility rates for non-invasive assessment of valvular incompetence. It appears also potentially reliable for the evaluation of calf musculo-venous pump efficiency.

1986 ◽  
Vol 1 (3) ◽  
pp. 211-215 ◽  
Author(s):  
A. Pecking ◽  
R. Cluzan ◽  
J.P. Desprez-Curely ◽  
P. Guerin

One thousand four hundred and fifty-five lymphoscintigraphies using a radio-labelled colloid were performed as an objective test for the diagnosis and the survey of lower limb oedemas. It is a non-invasive method involving only a subdermic bipedal injection into the first web space of each foot. Our results demonstrate that in chronic swollen legs due to venous causes occuring from post-thrombotic syndrome or varicose disease the lymphatic system can be insufficient (14.9% and 19.8% of these cases). Abnormal results are found in 91.3% of clinically primary lymphoedemas. In unilateral primary lymphoedemas the clinically healthy controlateral limb can be insufficient (25%). In post-traumatic lower limb oedemas the lymphatic flow remains normal while perilymphatic extravasation and dermal filling are always to be found at the trauma site. The lymphoscintigraphy is a simple, physiological and reliable test. The morphological findings based upon 1455 examinations allow us to think that this method may resolve the clinical problems without recourse to more invasive procedures. We can expect that in a few years this morphological study will be completed with a functional lymphatic test.


1979 ◽  
Vol 23 (3) ◽  
pp. 173
Author(s):  
J. A. D??RR ◽  
M. B. VALLOTTON ◽  
C. A. SIMON ◽  
B. KR??HENB??HL

The Lancet ◽  
1978 ◽  
Vol 311 (8064) ◽  
pp. 586-587 ◽  
Author(s):  
J.A. Dürr ◽  
M.B. Vallotton ◽  
C.A. Simon ◽  
B. Krähenbühl

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Keitaro Domae ◽  
Shigeru Miyagawa ◽  
Satsuki Fukushima ◽  
Teruya Nakamura ◽  
Yasushi Yoshikawa ◽  
...  

Background: Cardiac sympathetic activity, in general assessed by 123I-meta-iodobenzylguanidine cardiac scintigraphy (mIBG-s), has been shown to be a critical indicator to predict morbidity and mortality associated with chronic heart failure (HF). We herein hypothesized that nocturnal respiratory stability, which has been suggested to be impaired by autonomic dysfunction, may be correlated with sympathetic nerve activity in advanced HF. To test this hypothesis, we developed respiratory stability index (RSI), which is calculated by computer-based non-invasive measurements. Methods: Fifteen patients with chronic HF under intensive medical treatments including maximized beta-blocker therapy were enrolled. All patients echocardiographically displayed their ejection fraction (EF) less than 35%. Nocturnal respiratory signals were serially collected by the under-pillow sensor to evaluate the respiratory spectrum during asleep. RSI was calculated from average of the reciprocal of the standard deviation of respiratory spectral ranges (Figure). Results: RSI was successfully and reproducibly evaluated in all cohorts with an average value being 44±21. mIBG-s-based values to indicate sympathetic activity, such as heart-to-mediastinum ratio (HMR) or wash-out rate, showed abnormality in all cohorts. Of note, the RSI was strongly correlated with HMR (ρ=0.83, p<0.01) or wash-out rate (ρ=-0.87, p<0.01). In addition, RSI was significantly correlated with standard indicator of HF such as plasma brain natriuretic peptide level (ρ=-0.59, p<0.05), EF (ρ=0.73, p<0.05) or pulmonary capillary wedge pressure assessed by right heart catheter study (ρ=-0.70, p<0.05). Conclusions: RSI showed a significant correlation with degree of autonomic dysfunction assessed by mIBG-s in advanced HF of chronic stage. This non-invasive method might enable serial evaluation to predict cardiac events even in patients on home healthcare, though further validation is required.


1999 ◽  
Vol 14 (4) ◽  
pp. 146-150
Author(s):  
P. Zamboni ◽  
D. Quaglio ◽  
C. Cisno ◽  
F. Marchetti ◽  
L. Cisno ◽  
...  

Objective: To study the relationship between two non-invasive methods for determining ambulatory venous pressure (AVP) in primary chronic venous insufficiency of the lower limbs. Design: Comparison between ultrasonic AVP (US-AVP) and residual volume fraction (RVF) determined by means of air plethysmography (APG). Setting: Department of Surgery and Vascular Laboratory, University of Ferrara, Italy. Patients: Twenty-one subjects affected by primary chronic venous insufficiency (CVI). Main outcome measure: A comparison of the AVP values extrapolated from the change in ultrasonic diameter of the saphenous vein after exercise and from RVF values. Ultrasonographic extrapolation was also made by the means of the software Venometer and compared with manual assessment. Results: Linear regression analysis demonstrated that US-AVP values were significantly correlated with RVF values ( r = 0.86 and p<0.0001). Assessment by Venometer as compared with manual calculation showed a high degree of correlation ( r = 0.98), p<0.0001). Conclusions: The two methods for non-invasive assessment of AVP appear to be closely and significantly correlated. The Venometer allows reliable and rapid extrapolation of AVP values.


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