Comparison between Conventional and Fast Spin-Echo Stir Sequences

1996 ◽  
Vol 37 (3P2) ◽  
pp. 943-949 ◽  
Author(s):  
K. Hittmair ◽  
S. Trattnig ◽  
C. J. Herold ◽  
M. Breitenseher ◽  
J. Kramer

Purpose: To evaluate the common characteristics and differences in contrast behavior of short-TI-inversion-recovery (STIR) and short-TI-inversion-recovery fast spin-echo (TurboSTIR) sequences. Material and Methods: Phantoms doped with increasing doses of Gd-DTPA and a pork-fat phantom were used to evaluate the dependence of the STIR and TurboSTIR signals on the T1 relaxation time. Clinical TurboSTIR images were obtained from 30 patients with musculoskeletal abnormalities and compared to conventional STIR images in 15 cases and to postcontrast TurboSTIR images in another 15 cases. Results: In the phantom measurements, a significantly shorter inversion time (TI) was needed to achieve fat suppression on TurboSTIR images, and, with an identical number of signal averages, contrast-to-noise ratios were lower on TurboSTIR images. These differences between STIR and TurboSTIR can be attributed to the contribution of stimulated echoes to overall TurboSTIR signal and can be compensated by a shorter TI and a higher number of signal averages for TurboSTIR, respectively. With these adaptations, clinical TurboSTIR and STIR images showed an identical contrast behavior with fat suppression and a high sensitivity to pathological lesions but TurboSTIR saved a significant amount of scan time and reduced some types of artifacts. Contrast uptake impaired lesion conspicuity on TurboSTIR images. Conclusion: TurboSTIR sequences should replace conventional STIR sequences and should be performed before contrast administration.

1996 ◽  
Vol 9 (2) ◽  
pp. 157-164 ◽  
Author(s):  
T. Scarabino ◽  
G.M. Giannatempo ◽  
A. Simeone ◽  
F. Perfetto ◽  
T. Popolizio ◽  
...  

Gli autori illustrano gli aspetti tecnici, semeiologici ed applicativi delle tecniche di soppressione del grasso, con sequenza Fast Spin Echo (FSE) T2 pesata, in Neuroradiologia. L'uso di queste tecniche risulta obbligatorio con la FSE in quanto tale sequenza è caratterizzata da un alto segnale del grasso non solo in T1p, ma anche in T2p. Ciò comporta un'alterazione dell'imaging FSE, rispetto a quello Spin Echo convenzionale, con possibilità di mascherare tutte quelle patologie anch'esse ad alto segnale in T2p. I distretti che possono risentire di tale inconveniente comprendono quelle strutture con ampia componente di grasso quali quelle della testa (orbite, clivus, osso temporale) e soprattutto del rachide, particolarmente ricco di grasso a livello del midollo vertebrale e dello spazio epidurale. Le tecniche più utilizzate sono la CHESS-FSE (Chemical Shift Selective Saturation -FSE) e la STIR-FSE (Short TI Inversion Recovery-FSE). Con entrambe la soppressione del grasso risulta soddisfacente e rapida; ne consegue un aumento della visibilità diagnostica di lesioni quali quelle flogistiche o tumorali (specie ripetitive) altrimenti mascherate dall'alto segnale del grasso.


2009 ◽  
Vol 29 (2) ◽  
pp. 436-442 ◽  
Author(s):  
Richard Kijowski ◽  
Michael A. Woods ◽  
Kenneth S. Lee ◽  
Kuya Takimi ◽  
Huanzhou Yu ◽  
...  

2005 ◽  
Vol 18 (3) ◽  
pp. 357-363
Author(s):  
A. Lefkopoulos ◽  
A. Tzinas ◽  
E. Papadopoulou ◽  
A. Haritanti ◽  
D. Karanikolas ◽  
...  

Hippocampal Sclerosis (HS) is the most common cause of refractory temporal lobe epilepsy in adults. The aim of our study was to evaluate the diagnostic accuracy of conventional MRI sequences in HS and devise a cost-effective protocol of choice. Forty-eight patients, 26 men and 22 women, aged 16–55 years (mean age 29 years) with seizures refractory to medical treatment were evaluated by MR imaging. Hippocampal formation was assessed by transverse spin-echo (SE) T1-weighted (WI) and fast spin-echo (FSE) T2-WI sequences and by coronal Fluid Attenuated Inversion Recovery (FLAIR) and Inversion Recovery (IR) images. Increased signal intensity in FLAIR (93.2%), hippocampal atrophy (84.8%) and decreased signal intensity in IR images (72.7%) were the most common pathological findings of HS, while loss of the ipsilateral temporal lobe gray/white matter demarcation (66,7%) and amygdala sclerosis (15.1%) were encountered less frequently. FLAIR sequence was found to be more sensitive than FSE T2-WI in detecting HS. Thin coronal images were particularly helpful in assessing hippocampal formation, while IR images were additionally useful for the detection of possible co-existent cortical abnormalities. A brief review of the imaging findings of HS in more recent MR sequences is also made, though emphasizing that conventional SE T1-WI, FSE T2-WI, FLAIR and IR sequences, with a total examination duration of less than eight minutes, provide high sensitivity and specificity in the assessment of HS.


1996 ◽  
Vol 14 (9) ◽  
pp. 1017-1022 ◽  
Author(s):  
Kryss Y. Kojima ◽  
Thomas A. Demlow ◽  
Jerzy Szumowski ◽  
Stephen F. Quinn

Blood ◽  
2007 ◽  
Vol 110 (11) ◽  
pp. 4776-4776 ◽  
Author(s):  
Sikander Ailawadhi ◽  
Lyudmyla Derby ◽  
Kena C. Miller ◽  
Terry L. Mashtare ◽  
Gregory Wilding ◽  
...  

Abstract Background: Traditionally, bone marrow aspirate/biopsy (BM-Bx) has been used for diagnosis and quantification of the extent of disease as well as response to therapy in MM patients. This information is used to make decision for treatment initiation. Since MM is not a contiguous disease, marrow involvement can be patchy and BM-Bx may be misleading in assessing the true extent of the disease. BM-MRI is a non-invasive technique that can evaluate a large amount of marrow for tumor infiltration. We prospectively investigated the sensitivity of BM-MRI and compared its results with those obtained by BM-Bx as well as with the clinical stage of disease. Methods: All patients with the diagnosis of MM who had BM-MRI at our center were evaluable. Patients must have received a BM-Bx within 4 weeks of the BM-MRI. In these patients sagittal T1 and fast spin echo inversion recovery sequences of the cervical, thoracic and lumbosacral spine and coronal T1 and fast spin echo inversion recovery sequences of the sacrum and pelvic bones were reviewed on the MRI. Durie-Salmon (DS) staging criteria were used for correlation. To study the statistical relationship between pairs of ordinal variables the test corresponding to the Spearman correlation was used. To study the statistical relationship between nominal and ordinal variables, the Wilcoxon or Kruskal-Wallis test was used. A 0.05 nominal significance level was used in all testing. Following staging system was defined for evaluation of the involvement of the marrow by BM-MRI: A (0%), B (< 10%), C (10%–25%), D (26%–50%), E (> 50%). Results of this were then compared with the extent of involvement reported on histological evaluation of the BM-Bx. Results: A total of 50 patients (23 females and 27 males) were identified. Median age was 61.5 years (range 35–82 years) with 23 (46%) having stage IIIA disease. As per the staging system defined above, 6%, 10%, 10%, 22% and 52% of the patients had categories A, B, C, D and E involvement as per BM-MRI, respectively. Similarly, involvement observed on the BM-Bx was 8%, 24%, 22%, 16% and 30%, respectively. Categories of marrow involvement on BM-Bx and BM-MRI were concordant in 23 (46%) and discordant in 27 (54%) patients. Of the patients that showed discordance, 89% had a more extensive BM involvement detected by the BM-MRI and 11% had a higher reading on BM-Bx. The estimated Spearman correlation coefficient between MRI involvement and MM stage was 0.4849 (95% CI; 0.2494, 0.7205), showing a significant association between BM-MRI involvement and MM stage (p =0.0002). The estimated Spearman correlation coefficient between BM-Bx involvement and MM stage was 0.1775 (95% CI; −0.1406, 0.4956), showing no significant association between BM-Bx involvement and MM stage (p = 0.2764). Conclusions: We demonstrate for the first time that BM-MRI is a more sensitive technique to assess the true disease burden in MM and is significantly better than BM-Bx. We also observe that the extent of marrow infiltration noted on the BM-MRI correlates significantly with other prognostic characteristics like DS stage. Based on this observation we recommend that BM-MRI should be considered as part of the pre-treatment evaluation of patients with multiple myeloma.


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