A General Practice Evaluation of Selexid Suspension as a Treatment for Acute Urinary Tract Infection

1982 ◽  
Vol 10 (1) ◽  
pp. 35-38 ◽  
Author(s):  
I C Murison ◽  
Dileas M Sweetenham

Fifty-seven general practice patients (fifty-five females and two males) with acute uncomplicated cystitis received a 5-day course of pivmecillinam suspension at a dose of 200 mg (2 sachets) three times a day. Positive bacteriological cultures were obtained from twenty-eight patients (49%) before treatment. The bacteriological cure rate was 100%. All patients experienced some relief of symptoms and thirty nine patients (68%) were completely symptom-free after treatment. Selexid suspension was generally well tolerated. Side effects were reported in only four patients (6%) and no patient had to stop treatment prematurely.

1981 ◽  
Vol 9 (1) ◽  
pp. 58-61 ◽  
Author(s):  
J G Winwick ◽  
S J Savage

This general practice study compared a 3-day course of a new preparation, Mictral, with a standard 7-day course of ampicillin in the treatment of uncomplicated urinary tract infection. Mictral achieved bacteriological cure in all infected patients by Day 4 while only 69% of infected patients in the ampicillin group were abacteriuric by Day 8. Symptomatic relief and the incidence of side-effects were similar for both groups. It is concluded that Mictral appears to be a useful addition to currently available therapy for urinary tract infection and merits further investigation.


1979 ◽  
Vol 17 (21) ◽  
pp. 81.1-83

Most urinary tract infections resolve without treatment, but if untreated some progress to acute pyelonephritis. Antimicrobial agents are therefore used routinely to relieve symptoms and to prevent further infection.


The Lancet ◽  
1971 ◽  
Vol 298 (7725) ◽  
pp. 615-618 ◽  
Author(s):  
K.F. Fairley ◽  
N.E. Carson ◽  
R.C. Gutch ◽  
P. Leighton ◽  
A.D. Grounds ◽  
...  

2021 ◽  
Vol 2 (3) ◽  
pp. 61-66
Author(s):  
Lev E. Belyi ◽  

Urinary tract infections remain one of the most common problems of modern medicine. In this regard, not only urologists, but also specialists of other specialties face urinary tract infection in their practice: internists, general practitioners, obstetricians and gynecologists. The growing resistance of uropathogs to antibiotics dictates the need for constant revision of the principles of antibacterial therapy of urinary tract infections. The article presents an analysis of two clinical cases: a sporadic episode of acute uncomplicated cystitis and an episode of recurrent urinary tract infection. The principles of modern diagnostics and therapeutic strategy are considered.


PEDIATRICS ◽  
1977 ◽  
Vol 60 (2) ◽  
pp. 245-247
Author(s):  
N. S. Ellerstein ◽  
T. D. Sullivan ◽  
T. Baliah ◽  
E. Neter

Trimethoprim/sulfamethoxazole and ampicillin therapy in children with acute urinary tract infection, whose microorganisms were susceptible to both drugs, proved to be of similar effectiveness. Side effects did not differ significantly between the two treatment groups.


1969 ◽  
Vol 14 (3) ◽  
pp. 76-81 ◽  
Author(s):  
J. S. Milne ◽  
A. W. Irons ◽  
G. Kennedy ◽  
Edith T. Wallace

In a general practice an attempt was made to determine the relative merits of cycloserine, sulphadimidine or nitrofurantoin in the treatment of urinary tract infection. Bacteriological follow-up continued for 2 years. The incidence of patients with symptoms and with significant bacteriuria before treatment was 13 per 1,000 females at risk. With a follow-up of 50 days nitrofurantoin and cycloserine had an apparent cure rate of 78 and 79 per cent respectively. Sulphadimidine had a cure rate of only 43 per cent due largely to a higher incidence of organisms resistant in vitro. Results after 2 years show that apparent cures are much fewer (nitrofurantoin 46%, cycloserine 36%, sulphadimidine 29%) and there is much less difference in the effectiveness of the various drugs. Only 4 patients stopped treatment because of drug toxicity. The results of intravenous pyelography in 155 patients suggest that rather than X-ray all patients with urinary-tract symptoms, prolonged bacteriological follow-up will reveal those in whom X-rays may be helpful.


2005 ◽  
Vol 12 (2) ◽  
pp. 77-83 ◽  
Author(s):  
YW Li ◽  
WL Yuen

Introduction Urinary tract infection is a common problem in females encountered in the Accident & Emergency Department. The increasing prevalence of Escherichia coli and other urine isolates resistant to trimethoprim-sulfamethoxazole and ampicillin enhances the use of nitrofurantoin as the first line therapy. A guideline of 3-day antibiotic in presumed uncomplicated cystitis has been proved to be of improved cost-effectiveness. Objective To study the outcome and efficiency of 3-day antibiotic treatment in presumed acute uncomplicated cystitis in women in the Accident & Emergency Department. Methods This was a prospective study on women aged 18–55 years with presumed uncomplicated cystitis from January to June 2004. A telephone survey was conducted to assess the clinical response, adverse effect and compliance of the treatment. Results Initially 83 patients were recruited in the study, but only 76 patients' outcomes could be traced by telephone survey and the computer system in public hospitals. Fifty-eight patients (76.3%) had good clinical response with symptoms resolved usually on day 2. Though 48.1% of the patients reported side effects with mainly gastrointestinal discomfort, most were mild and tolerable. The overall compliance was above 80%. Conclusion Three-day nitrofurantoin is an effective, inexpensive treatment for acute uncomplicated cystitis, which is a common disorder in females. Guidelines on the management of this large group of patients would help to conserve health care costs, improve compliance and reduce the emergence of resistance strains.


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