scholarly journals Cardiac Output Measurements by Thermal Dilution in Anaesthesia and Intensive Care

1973 ◽  
Vol 1 (5) ◽  
pp. 393-399 ◽  
Author(s):  
James Loughman

Cardiac output measurements are rarely used in the evaluation of cardiovascular disorders encountered in anaesthesia and intensive care. The thermal dilution technique provides a practical method for its widespread introduction and only requires techniques already familiar to people working in this field. Adequate commercial equipment is now available in Australia, and a consideration of its use is presented. The principle of indicator dilution and its application is described. A comparison is made of dye and thermal dilution, and the relative advantages of two catheter systems for use in thermal dilution are discussed. The reported complications and those experienced by us are presented.

1965 ◽  
Vol 209 (4) ◽  
pp. 723-726 ◽  
Author(s):  
H. Victor Murdaugh ◽  
Eugene D. Robin ◽  
J. Eugene Millen ◽  
William F. Drewry

A dye-dilution technique has been adapted for the measurement of cardiac output in the elasmobranch, Squalus acanthias. Cardiac output averaged 1.60 ± 1.00 liter/kg per hr in 26 fish. Small fish showed a relatively high cardiac index (liters/kg per hr) as compared with large fish. The use of this technique permits sequential cardiac output measurements with the maintenance of an intact physiological status. This technique should permit quantitation of exchange of a variety of substances across the gill membranes.


1986 ◽  
Vol 14 (4) ◽  
pp. 294-297 ◽  
Author(s):  
JOHAN F. VANDENBOGAERDE ◽  
RUDY G. SCHELDEWAERT ◽  
DIRK L. RIJCKAERT ◽  
DENIS L. CLEMENT ◽  
FRANCIS A. COLARDYN

1981 ◽  
Vol 241 (3) ◽  
pp. H442-H448 ◽  
Author(s):  
K. R. Fitzgerald ◽  
C. F. Babbs ◽  
H. A. Frissora ◽  
R. W. Davis ◽  
D. I. Silver

Cardiac output during cardiopulmonary resuscitation (CPR) was measured by a modified indicator-dilution technique in 20 anesthetized dogs (6-12 kg), during repeated 1- to 2-min episodes of electrically induced ventricular fibrillation, by a mechanical chest compressor and ventilator. With compression rates from 20 to 140/min and compression durations (duty cycles) from 10 to 90% of cycle time, cardiac output (CO) was predicted by the equation: CO = CR . SVmax . [DC/(k1 . CR + DC)] . [(1 — DC)/k2 . CR + 1 - DC)], where CR is compression rate, DC is duty cycle, SVmax (19 ml) is the effective capacity of the pumping chamber, and k1 (0.00207 min) and k2 (0.00707 min) are ejection and filling constants. This expression predicts maximal CO for DC = 0.40 and cR = 126/min and 90-100% of maximal CO for 0.3 less than DC less than 0.5 and 70 less than CR less than 150/min. Such mathematical analysis may prove useful in the optimization of CPR.


1979 ◽  
Vol 36 (9) ◽  
pp. 1156-1157
Author(s):  
Edward J. Mattea ◽  
Anthony N. Paruta ◽  
Leonard R. Worthen

Author(s):  
Theodore G Papaioannou ◽  
Dimitrios Xanthis ◽  
Antonis Argyris ◽  
Pavlos Vernikos ◽  
Georgia Mastakoura ◽  
...  

Non-invasive monitoring of cardiac output is a technological and clinical challenge, especially for critically ill, surgically operated, or intensive care unit patients. A brachial cuff-based, automated, oscillometric device used for blood pressure and arterial stiffness ambulatory monitoring (Mobil-O-Graph) provides a non-invasive estimation of cardiac output values simultaneously with regular blood pressure measurement. The aim of the study was to evaluate the feasibility of this apparatus to estimate cardiac output in intensive care unit patients and to compare the non-invasive estimated cardiac output values with the respective gold standard method of thermodilution during pulmonary artery catheterization. Repeated sequential measurements of cardiac output were performed, in random order, by thermodilution (reference) and Mobil-O-Graph (test), in 24 patients hospitalized at intensive care unit. Reproducibility and accuracy of the test device were evaluated by Bland–Altman analysis, intraclass correlation coefficient, and percentage error. Mobil-O-Graph underestimated significantly the cardiac output by −1.12 ± 1.38 L/min ( p < 0.01) compared to thermodilution. However, intraclass correlation coefficient was >0.7 indicating a fair agreement between the test and the reference methods, while percentage error was approximately 39% which is considered to be within the acceptable limits. Cardiac output measurements were reproducible by both Mobil-O-Graph (intraclass correlation coefficient = 0.73 and percentage error = 27.9%) and thermodilution (intraclass correlation coefficient = 0.91 and percentage error = 26.7%). We showed for the first time that cardiac output estimation in intensive care unit patients using a non-invasive, automated, oscillometric, cuff-based apparatus is reproducible (by analyzing two repeated cardiac output measurements), exhibiting similar precision to thermodilution. However, the accuracy of Mobil-O-Graph (error compared to thermodilution) could be considered fairly acceptable. Future studies remain to further examine the reliability of this technology in monitoring cardiac output or stroke volume acute changes which is a more clinically relevant objective.


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