Prescription and Assessment of Tidal Peritoneal Dialysis Delivery with a Specific Equilibration Test

1996 ◽  
Vol 16 (3) ◽  
pp. 295-301 ◽  
Author(s):  
Alberto Edefonti ◽  
Marina Picca ◽  
Geltrude Consalvo ◽  
Luciana Ghio ◽  
Beatrice Damiani ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Pediatric Nephrology ◽  
Correlation Coefficients ◽  
Dialysis Unit ◽  
Time Points ◽  
Stage Renal Disease ◽  
End Stage ◽  
A Prospective Study ◽  
Clinical Conditions ◽  
Tidal Peritoneal Dialysis

Objective To propose a simplified equilibration test specific for tidal peritoneal dialysis (TPD) that will overcome the inconveniences of the measurement of TPD peritoneal solute clearances through whole dialysate collection. This will enable the prediction of peritoneal creatinine and urea clearances, the suitability of patients for TPD, and routine assessment of TPD delivery. Design In a prospective study, patients had a standardized TPD run, and dialysate-to-plasma (DIP) ratios for creatinine and urea were calculated at various TPD and peritoneal equilibration test (PET) time points and on total TPD dialysate. Solute clearances were estimated and measured, and correlation coefficients were obtained among all these variables. Setting Dialysis unit of a pediatric nephrology department and patients’ homes. Patients Eleven pediatric patients with end-stage renal disease in stable clinical conditions treated with TPD. Interventions Dialysate and blood sample collections. Main Outcome Measures DIP ratios for creatinine and urea at the fifth and seventh TPD exchanges, at 15–,30–,60, and 120-minute PETtimes, and on total TPD dialysate and TPD peritoneal creatinine and urea clearances. Results Correlation coefficients between PET -derived and total TPD dialysate-derived DIP ratios, and those between PET -derived and measured creatinine and urea clearances were more significant at the 120-minute PET time point compared with the other PET time points. Best correlations were obtained at the fifth and seventh TPD exchanges. DIP ratios for creatinine and urea of the fifth and seventh TPD exchanges correlated significantly with the DIP ratios calculated from total TPD dialysate. A significant correlation was also found between peritoneal creatinine and urea clearances on total dialysate volume (measured clearances) and those derived from the dialysate collection of the fifth and seventh TPD exchanges (estimated clearances) -that based on the seventh exchange being slightly more significant. Moreover, the estimated clearances derived from the seventh exchange were within 10% of the measured value in 90.9% of patients both for creatinine and urea. Conclusion The significant correlation between measured and estimated peritoneal creatinine and urea clearances and the low percentage of underestimates of measured clearances obtained using the seventh TPD exchange-derived indices confirm the accuracy of the DIP ratios for creatinine and urea derived from any exchange after the fifth (preferably the seventh) of a standardized TPD run in estimating peritoneal creatinine and urea clearances. This method could represent a simple and accurate means for prescribing TPD and routinely assessing TPD delivery.

scholarly journals Urgent-Start Peritoneal Dialysis: The First Year of Brazilian Experience

2017 ◽  
Vol 44 (4) ◽  
pp. 283-287 ◽  
Author(s):  
Dayana Bitencourt Dias ◽  
Marcela Lara Mendes ◽  
Vanessa Burgugi Banin ◽  
Pasqual Barretti ◽  
Daniela Ponce
Keyword(s):  
Peritoneal Dialysis ◽  
Survival Rates ◽  
High Volume ◽  
Infectious Complications ◽  
Chronic Patients ◽  
Safe Alternative ◽  
Dialysis Unit ◽  
Technique Survival ◽  
Stage Renal Disease ◽  
End Stage

Background: This study aimed to evaluate mechanical and infectious complications associated with urgent-start peritoneal dialysis (PD) and patients and technique survival in the first 180 days. Methods: It was a prospective study that evaluated chronic patients who started unplanned PD using high-volume PD (HVPD) right after (<72 h) PD catheter placement. After hospital discharge, patients were treated with intermittent PD on alternate days in a dialysis unit until family training was provided. Results: Fifty-one patients fulfilling the following criteria were included: age was 62.1 ± 15 years, with diabetes as the main etiology of end-stage renal disease (39%), and uremia as the main dialysis indication (76%). Metabolic and fluid controls were achieved after 3 sessions of HVPD, and patients remained in intermittent PD for 23.2 ± 7.2 days. Mechanical complications occurred in 25.7% and peritonitis rate was 0.5 episode/patient-year. In the first 6 months, technique and patients survival rates were 86 and 82.4% respectively. Conclusion: The PD modality was a feasible and safe alternative to hemodialysis in the urgent-start dialysis.

Development of the “Peritoneal Dialysis First” Model in Hong Kong

2007 ◽  
Vol 27 (2_suppl) ◽  
pp. 53-55 ◽  
Author(s):  
Alex Wai-Yin Yu ◽  
Ka-Foon Chau ◽  
Yiu-Wing Ho ◽  
Philip Kam-Tao Li
Keyword(s):  
Hong Kong ◽  
Peritoneal Dialysis ◽  
Survival Rates ◽  
Chronic Hemodialysis ◽  
Dialysis Unit ◽  
Number Of Patients ◽  
Maintenance Dialysis ◽  
The 1960S ◽  
Stage Renal Disease ◽  
End Stage

Maintenance dialysis is an expensive treatment modality for patients with end-stage renal-disease (ESRD). The number of patients on maintenance dialysis is rising rapidly and will reach 2.5 million globally by 2010. The predicted expenditure will be US$1 trillion. Since the 1960s, Hong Kong has faced financial restraints on the provision of dialysis. Continuous ambulatory peritoneal dialysis (CAPD) and automated peritoneal dialysis at home were found to be less expensive than in-centre chronic hemodialysis. The development of a “peritoneal dialysis first” (PD-First) policy has contributed significantly to a successful dialysis program in Hong Kong since 1960. Currently in Hong Kong, 80% of ESRD patients on maintenance dialysis are on PD, mainly CAPD; 20% are on hemodialysis. The success of the PD-First policy is a combination of accumulated experience of PD in each dialysis unit that has at least 200 CAPD patients under care and of impressive technique and patient survival rates for this modality. Concerted effort by government and charity organizations and commitment on the part of nephrologists and nursing staff to patient education are also important in making the PD program in Hong Kong a successful one.

scholarly journals MP023INNATE IMMUNITY DYSFUNCTION IN END-STAGE RENAL DISEASE: A PROSPECTIVE STUDY ON PERITONEAL DIALYSIS AND HEMODIALYSIS

2016 ◽  
Vol 31 (suppl_1) ◽  
pp. i349-i349
Author(s):  
Rita Leal ◽  
José Simplício ◽  
Ana Galvão ◽  
Paulo R. Santos ◽  
Helena O. Sá ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Renal Disease ◽  
Prospective Study ◽  
End Stage Renal Disease ◽  
Stage Renal Disease ◽  
End Stage ◽  
A Prospective Study

scholarly journals Biomarkers Associated with Vascular Calcification in Peritoneal Dialysis

2016 ◽  
Vol 36 (3) ◽  
pp. 262-268 ◽  
Author(s):  
Juan C. Ramirez-Sandoval ◽  
Ivan Casanova ◽  
Alejandro Villar ◽  
F. Enrique Gomez ◽  
Cristino Cruz ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Vascular Calcification ◽  
End Stage Renal Disease ◽  
Fibroblast Growth Factor 23 ◽  
Correlation Coefficients ◽  
X Rays ◽  
Stage Renal Disease ◽  
End Stage ◽  
Fgf 23 ◽  
Spearman’S Correlation

Background Vascular calcification is strongly associated with cardiovascular disease and mortality. However, some factors related to vascular calcification in patients with end-stage renal disease receiving peritoneal dialysis (PD) remain unknown. This study aimed to evaluate the associations of osteoprotegerin (OPG), osteopontin (OPN), osteocalcin (OCN), fibroblast growth factor 23 (FGF-23), magnesium, and phosphate clearance with vascular calcification in PD subjects, assessed by plain radiographs. Methods Simple vascular calcification scores (SVCS) obtained from plain X-rays of the pelvis and hands, and the Kauppila Index (KI) from lateral lumbar X-rays were assessed in 76 adults receiving PD for ≥ 6 months (43 women, median age 39 years, median time on PD 1.4 years). Levels of OPG, OPN, OCN, and FGF-23 were determined by luminometry. Results Serum OPG levels were higher in subjects with vascular calcification ( n = 22 with SVCS > 3; n = 19 with KI > 7) compared with those with less calcification ( p < 0.001). Spearman's correlation coefficients between OPG and SVCS and KI were r = 0.49 and r = 0.51, respectively (both p < 0.001). Subjects with vascular calcification had significantly lower renal phosphate clearance. Multiple regression analysis showed that vascular calcification assessed by SVCS was associated with age ( r = 0.2, p = 0.042), diabetes mellitus ( r = 2.4, p < 0.001), body mass index (BMI) ( r = 0.09, p = 0.037), and OPG ( r = 0.22, p = 0.001). Vascular calcification assessed by KI was associated with age ( r = 0.16, p < 0.001), time on PD ( r = 0.54, p = 0.001) and OPG ( r = 0.08, p = 0.04). Osteocalcin, OPN, FGF-23, and magnesium were not associated with vascular calcification. Conclusions Higher levels of OPG were consistently associated with vascular calcification in subjects on PD.

scholarly journals Assisted Peritoneal Dialysis for Older People with End-Stage Renal Disease: The French and Danish Experience

2015 ◽  
Vol 35 (6) ◽  
pp. 663-666 ◽  
Author(s):  
Clémence Béchade ◽  
Thierry Lobbedez ◽  
Per Ivarsen ◽  
Johan V. Povlsen
Keyword(s):  
Peritoneal Dialysis ◽  
Renal Disease ◽  
Older People ◽  
End Stage Renal Disease ◽  
Advanced Age ◽  
Dialysis Unit ◽  
Stage Renal Disease ◽  
End Stage ◽  
The Cost ◽  
Assisted Peritoneal Dialysis

Older people are the largest and fastest growing group of patients with end-stage renal disease (ESRD), and, due to advanced age and a heavy burden of comorbidities, they are usually not candidates for renal transplantation or home-based dialysis treatment. Some of the barriers for home treatment are non-modifiable, but the majority of physical disabilities and psychosocial problems can be overcome provided that assistance is offered to the patients at home. In the present review, we describe the programs for assisted peritoneal dialysis (PD) in France and Denmark, respectively. In both nations, assisted PD is totally publicly funded, and the cost of assisted PD is comparable to the cost of in-center HD. Assisted continuous ambulatory PD (aCAPD) is the preferred modality in France whereas assisted automated PD (aAPD) is the preferred modality in Denmark. Assistants are professional nurses or healthcare technicians briefly educated by expert PD nurses from the dialysis unit. The establishment of a program for assisted PD may increase the number of patients actually treated with PD and may reduce the risk of PD technique failure and prolong PD duration. Compared with autonomous PD patients, patients on assisted PD may have shorter patient survival and peritonitis-free survival indicating that, besides advanced age and the burden of comorbidities, dependency on help may be an independent risk factor for poorer outcome. Assisted PD is an evolving dialysis modality, and may in the future prove to be a feasible complementary alternative to in-center hemodialysis (HD) for the growing group of dependent older patients with ESRD.

Iron Chelation Therapy in CAPD: A New and Effective Treatment of Iron Overload Disease in Esrd Patients

1983 ◽  
Vol 3 (2) ◽  
pp. 99-101 ◽  
Author(s):  
Glen H Stanbaugh ◽  
A. W, Holmes Diane Gillit ◽  
George W. Reichel ◽  
Mark Stranz
Keyword(s):  
Peritoneal Dialysis ◽  
Iron Overload ◽  
End Stage Renal Disease ◽  
Chelation Therapy ◽  
Iron Chelation ◽  
Iron Chelation Therapy ◽  
Peritoneal Dialysate ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

A patient with end-stage renal disease on CAPD, and with massive iron overload is reported. This patient had evidence of myocardial and hepatic damage probably as a result of iron overload. Treatment with desferoxamine resulted in removal of iron in the peritoneal dialysate. On the basis of preliminary studies in this patient it would appear that removal of iron by peritoneal dialysis in conjunction with chelation therapy is safe and effective. This finding should have wide-ranging signficance for patients with ESRD.

scholarly journals Delayed bowel perforation after instilling over warmed peritoneal dialysate

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Xueli Lai ◽  
Mingming Nie ◽  
Xiaodong Xu ◽  
Yuanjie Chen ◽  
Zhiyong Guo
Keyword(s):  
Peritoneal Dialysis ◽  
Bowel Perforation ◽  
Exploratory Laparotomy ◽  
Peritoneal Dialysis Patient ◽  
Case Presentation ◽  
Abdominal Organs ◽  
Home Based ◽  
Dialysis Solution ◽  
Stage Renal Disease ◽  
End Stage

Abstract Background Peritoneal dialysis (PD) is a safe and home-based treatment for end-stage renal disease (ESRD) patients. The direct thermal damage of abdominal organs is very rare. Case presentation We report a peritoneal dialysis patient presented abdominal pain and feculent effluent 3 weeks after he instilled hot dialysis solution. In spite of emergency exploratory laparotomy and active treatment, the patient died of septic shock. Biopsy revealed necrosis and perforation of the intestines. Conclusions Delayed bowel perforation by hot fluid is very rare. Standardized performance is of the first importance for peritoneal dialysis patients.

Outcomes of infants <28 days old treated with peritoneal dialysis for end-stage renal disease

2009 ◽  
Vol 24 (10) ◽  
pp. 2035-2039 ◽  
Author(s):  
Michelle N. Rheault ◽  
Jurat Rajpal ◽  
Blanche Chavers ◽  
Thomas E. Nevins
Keyword(s):  
Peritoneal Dialysis ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Stage Renal Disease ◽  
End Stage
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