Magnetic Resonance Imaging Contrast Agents and the Nuclear Pharmacist

The nuclear pharmacist works with a very specific group of drugs. These drugs generally exhibit no toxic effects and are used almost exclusively for diagnosis. In the past these have been the radioactive drugs used in nuclear medicine and the iodinated contrast agents used in radiology. However, with the advent of magnetic resonance imaging (MRI), there is an additional class of drugs used in radiology, the magnetopharmaceuticals. These drugs are designed especially for increasing diagnostic sensitivity with MRI. This article is intended to provide topical insight into the basics of MRI and magnetopharmaceuticals.

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The Application Of Molecular Sieves As Magnetic Resonance Imaging Contrast Agents

MRS Proceedings ◽

10.1557/proc-233-225 ◽

1991 ◽

Vol 233 ◽

Cited By ~ 6

Author(s):

Kenneth J. Balkus ◽

Iwona Bresinska ◽

Stanislaw Kowalak ◽

Stuart W. Young

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Contrast Agents ◽

Molecular Sieves ◽

Mri Contrast Agents ◽

Paramagnetic Species ◽

Resonance Imaging ◽

Mri Contrast ◽

Magnetic Resonance Imaging Contrast ◽

Magnetic Resonance Imaging Mri

ABSTRACTThe application of zeolite molecular sieves as Magnetic Resonance Imaging (MRI) contrast agents is presented. Recent progress is described for X, Y and A type zeolites modified with paramagnetic species.

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A poly(ε-caprolactone)–poly(glycerol)–poly(ε-caprolactone) triblock copolymer for designing a polymeric micelle as a tumor targeted magnetic resonance imaging contrast agent

Journal of Materials Chemistry B ◽

10.1039/c7tb01967j ◽

2017 ◽

Vol 5 (42) ◽

pp. 8408-8416 ◽

Cited By ~ 6

Author(s):

Yi Cao ◽

Min Liu ◽

Ye Kuang ◽

Guangyue Zu ◽

Dangsheng Xiong ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Contrast Agents ◽

Triblock Copolymer ◽

Polymeric Micelle ◽

Resonance Imaging ◽

High Relaxivity ◽

Magnetic Resonance Imaging Contrast ◽

Magnetic Resonance Imaging Mri ◽

Imaging Contrast Agent

Gadolinium-based macromolecular contrast agents (CAs) with favorable biocompatibility, targeting specificity, and high relaxivity properties are desired for magnetic resonance imaging (MRI) of tumors.

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Magnetic resonance imaging in study of lungs

Medical Visualization ◽

10.24835/1607-0763-2019-4-10-23 ◽

2019 ◽

pp. 10-23

Author(s):

T. A. Akhadov ◽

S. Yu. Guryakov ◽

M. V. Ublinsky

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Medical Society ◽

Resonance Imaging ◽

Iodinated Contrast ◽

Long Time ◽

Women And Children ◽

Magnetic Resonance Imaging Mri ◽

A Current ◽

Lung Mri

For a long time, there was a need to apply magnetic resonance imaging (MRI) technique for lung visualization in clinical practice. The development of this method is stimulated by necessity of the emergence of an alternative to computed tomography, especially when radiation and injection of iodine-containing contrast agents are contraindicated or undesirable, for example, in pregnant women and children, people with intolerance to iodinated contrast. One of the reasons why lung MRI is still rarely used is lack of elaborated standardized protocols that would be adapted to clinical needs of medical society. This publication is a current literature review on the use of MRI in lung studies.

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Biocompatible dextran-coated gadolinium-doped cerium oxide nanoparticles as MRI contrast agents with high T1 relaxivity and selective cytotoxicity to cancer cells

Journal of Materials Chemistry B ◽

10.1039/d1tb01147b ◽

2021 ◽

Author(s):

Anton Popov ◽

Maxim Artemovich Abakumov ◽

Irina Savintseva ◽

Artem Ermakov ◽

Nelly Popova ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Contrast Agents ◽

Mri Contrast Agents ◽

Cerium Oxide Nanoparticles ◽

Oxide Nanoparticles ◽

Resonance Imaging ◽

Mri Contrast ◽

Selective Cytotoxicity ◽

Magnetic Resonance Imaging Mri

Gd-based complexes are widely used as magnetic resonance imaging (MRI) contrast agents. The safety of previously approved contrast agents is questionable and is being re-assessed. The main causes of concern...

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