Pityriasis rosea-like adverse reaction to atenolol

2015 ◽  
Vol 35 (3) ◽  
pp. 229-231 ◽  
Author(s):  
Aİ Güleç ◽  
H Albayrak ◽  
O Kayapinar ◽  
S Albayrak

A 56-year-old female patient was presented with diffuse, bright red to violet colour, scaly patches on trunk and extremities after using a hypertension drug, atenolol. The patient was diagnosed as pityriasis rosea-like adverse reaction to atenolol based on her history, dermatological examination and histopathological findings. To the best of our knowledge, this is the first reported case of pityriasis rosea-like adverse reaction to atenolol that is widely used in hypertension treatment.

10.3823/2544 ◽  
2018 ◽  
Vol 11 ◽  
Author(s):  
Adriana Kamilly Leitão Pitman Machado ◽  
Danielle Oliveira Sousa ◽  
Miguel Saraty de Oliveira ◽  
Débora Bacellar Cruz Nunes ◽  
Michelle Fonseca Goiabeira ◽  
...  

Background: Dohi's Reticulated Acropigmentation is a rare autosomal dominant genodermatosis with high penetrance, characterized by small, irregular, hypo and hyperpigmented macules on the dorsal surface of the distal extremities. Case: The authors report a case of Dohi’s Reticulated Acropigmentation in a 61 years old female patient. The patient complained of spots on hands, feet and posteriorly face involvement since she was 7 years old. Conclusion: Dohi's Reticulated Acropigmentation is a rare clinical condition, which usually appear in childhood and commonly interrupt their onset before adolescence. The diagnosis is based on clinical data, physical examination and histopathological findings. The treatment is unsatisfactory and still no therapy is proposed.


2018 ◽  
Vol 14 (4) ◽  
pp. 225-227
Author(s):  
Radha Baral ◽  
Bidhata Ojha ◽  
Dipshikha Bajracharya ◽  
Sumit Singh

Myoepithelioms are rare benign salivary gland tumors representing 1–1.5% of all salivary gland tumors. It was once considered to be one end of the histologic spectrum of pleomorphic adenoma (PA), but myoepitheliomas today are believed to be distinct entity. Herein we report a case of myoepithelioma in a 49 years old female patient with the history of swelling in the soft and hard palate. The diagnosis was made on the basis of histopathological findings and immunohistochemical report.  


2017 ◽  
Vol 24 (2) ◽  
pp. 231-233 ◽  
Author(s):  
Giancarlo Coghe ◽  
Laura Atzori ◽  
Jessica Frau ◽  
Giuseppe Fenu ◽  
Lorena Lorefice ◽  
...  

We report the case of a 42-year-old female patient who developed peculiar skin lesions due to subcutaneous polyethylene glycol (PEG) interferon beta-1a. The dermatological examination showed hypochromic macules that had coalesced into a 10-cm-diameter patch. On the abdomen injection sites, there was a greyish diffuse hyperpigmentation arranged irregularly in annular macules. Fungal infection, vitiligo and pityriasis alba were excluded. After 6 months, the lesions had worsened. This is the first case of localized pigmentation disorder reported with interferon beta, and while the clinical findings are not ascribable to vitiligo or interferon-related facial/mucosal hyperpigmentation, they may partially share the underlining mechanisms.


Author(s):  
L Atzori ◽  
C Ferreli ◽  
AL Pinna ◽  
N Aste

2021 ◽  
Vol 49 (5) ◽  
pp. 030006052110155
Author(s):  
Jie Yang ◽  
Shicheng Jiao ◽  
Min Zhang

Pruritus pigmentosa is a skin disease mainly characterized by pruritus, inflammatory rash and reticular and macular pigmentation. The disease more commonly affects young women and may persist for several years. In this article, we report a case of a 20-year-old female patient who presented with erythema and blisters on the neck and trunk with pruritus for 20 days. Dermatological examination revealed a reticular distribution of erythema on the chest and abdomen and some areas of erythema covered with crusts. Additionally, blisters and bullae with clear fluid and negative Nikolsky’s sign were noted. On the neck and back, erythema was also in a reticular distribution, and erythema secondary to erosion and/or crusts was present. In addition, histopathological analysis of the lesions showed hyperkeratosis and intraepidermal multilocular vesiculation and confirmed increased migration of inflammatory cells into the epidermis and infiltration of inflammatory cells, including lymphocytes, histiocytes and eosinophils, in the superficial dermis. The expression levels of IgG, IgM, IgA and C3 were all negative. This patient was diagnosed with prurigo pigmentosa, and the condition improved after treatment with minocycline.


Author(s):  
Julio Sepúlveda-Saavedra ◽  
Beatriz González-Corona ◽  
Víctor A. Tamez Rodríguez ◽  
Ma. Victoria Bermúdez de Rocha ◽  
Alfredo Piñeyro López

It has been shown in previous studies that the toxin T-514 isolated from K. humboldtiana induces severe damage to the lung in treated rodents. Histopathological findings include edema, and alveolar hemorrage. However, the ultraestructure of the lesion has not been investigated. In this study we used two species of rodents: Hamster and guinea pig, and a primate: Macaca fascicularis. Animals received different single dosis of the toxin via intraperitoneal. Control animals received only the vehicle (propylen glycol). Inmediately after spontaneous death, lung samples were fixed in Karnovsky-Ito fixative, post fixed in osmium tetroxide and embedded in epon. Thin sections were prepared with an Ultratome V LKB, stained with uranly acetate and lead citrate, and studied in an electron microscope Zeiss-EM109.


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