Divergent Differentiation In Malignant Soft Tissue Neoplasms: The Paradigm of Liposarcoma and Malignant Peripheral Nerve Sheath Tumor

2005 ◽  
Vol 13 (1) ◽  
pp. 19-28 ◽  
Author(s):  
Peter Pytel ◽  
Jerome B. Taxy ◽  
Thomas Krausz
Keyword(s):  
Soft Tissue ◽  
Peripheral Nerve ◽  
Soft Tissue Neoplasms ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath ◽  
Divergent Differentiation ◽  
Malignant Soft Tissue

scholarly journals A Rare Malignant Peripheral Nerve Sheath Tumor of the Maxilla Mimicking a Periapical Lesion

2016 ◽  
Vol 2016 ◽  
pp. 1-5
Author(s):  
José Alcides Arruda ◽  
Pamella Álvares ◽  
Luciano Silva ◽  
Alexandrino Pereira dos Santos Neto ◽  
Cleomar Donizeth Rodrigues ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Peripheral Nerve ◽  
Soft Tissue Sarcomas ◽  
Malignant Neoplasm ◽  
Surgical Approaches ◽  
Type I ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath ◽  
Malignant Soft Tissue Tumor

Malignant peripheral nerve sheath tumor is a malignant neoplasm that is rarely found in the oral cavity. About 50% of this tumor occurs in patients with neurofibromatosis type I and comprises approximately 10% of all soft tissue sarcomas of head and neck region. Intraosseous malignant peripheral nerve sheath tumor of the maxilla is rare. This article is the first to address malignant peripheral nerve sheath tumor of the maxilla presenting as a periapical radiolucency on nonvital endodontically treated teeth in the English medical literature. Surgical approaches to malignant soft tissue tumor vary based on the extent of the disease, age of the patient, and pathological findings. A rare case of intraosseous malignant peripheral nerve sheath tumor is reported in a 16-year-old woman. The patient presented clinically with a pain involving the upper left incisors region and with defined unilocular periapical radiolucency lesion involved between the upper left incisors. An incisional biopsy was made. Histological and immunohistochemical examination were positive for S-100 protein and glial fibrillary acidic protein showed that the lesion was an intraosseous malignant peripheral nerve sheath tumor of the maxilla. Nine years after the surgery, no regional recurrence was observed.

Malignant Peripheral Nerve Sheath Tumor With Divergent Differentiation

2003 ◽  
Vol 127 (3) ◽  
pp. e147-e150 ◽  
Author(s):  
Li Huang ◽  
Carmen Espinoza ◽  
Ronald Welsh
Keyword(s):  
African American ◽  
Peripheral Nerve ◽  
Pulmonary Embolus ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath ◽  
Spindle Cells ◽  
Divergent Differentiation ◽  
Rare Cells ◽  
Tumor Death

Abstract Right posterior thigh malignant peripheral nerve sheath tumor with malignant glandular and rhabdomyoblastic components was diagnosed in a 24-year-old African American man. Malignant glands and rhabdomyoblastic cells were admixed with the spindle cells. Immunohistochemistry demonstrated spindle cells positive for S100 and vimentin; the glandular component was positive for chromogranin, and rare cells were positive for CK20 but negative for CK7. Rhabdomyoblastic cells were positive for muscle-specific actin and desmin. A single pulmonary metastasis occurred 5 months after surgical resection of the tumor. Death occurred 1 month later and was probably due to a pulmonary embolus.

scholarly journals Malignant peripheral nerve sheath tumor with divergent differentiation

2009 ◽  
Vol 52 (1) ◽  
pp. 74 ◽  
Author(s):  
TN Suresh ◽  
ML Harendra Kumar ◽  
C.S.B.R Prasad ◽  
R Kalyani ◽  
K Borappa
Keyword(s):  
Peripheral Nerve ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath ◽  
Divergent Differentiation

scholarly journals Huge Intrathoracic Malignant Peripheral Nerve Sheath Tumor in an Adolescent with Neurofibromatosis Type 1

2014 ◽  
Vol 2014 ◽  
pp. 1-5
Author(s):  
Jong Hyung Yoon ◽  
Hyun-Sung Lee ◽  
Jong In Chun ◽  
Seog-Yun Park ◽  
Hyeon Jin Park ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Peripheral Nerve ◽  
Neurofibromatosis Type 1 ◽  
Neurofibromatosis Type ◽  
The Body ◽  
Nerve Sheath Tumor ◽  
Review Of The Literature ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath

Malignant peripheral nerve sheath tumor (MPNST) is a rare soft tissue malignancy usually found in patients with neurofibromatosis type 1 (NF1) with a poor outcome. Although MPNST can be found in any part of the body including head and neck or extremities, intrathoracic MPNST with or without NF1 is uncommon, especially in children or adolescents. Reported herein is a case of huge intrathoracic MPNST in a 16-year-old girl with NF1, and a brief review of the literature.

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