Ectopic Liver Within the Placental Parenchyma of a Stillborn Fetus

2017 ◽  
Vol 21 (5) ◽  
pp. 486-488 ◽  
Author(s):  
Rasleen Saluja ◽  
Ona Faye-Petersen ◽  
Debra S Heller
Keyword(s):  
Umbilical Cord ◽  
Liver Tissue ◽  
Hepatocellular Adenoma ◽  
Liver Cells ◽  
Rare Site ◽  
Ectopic Liver ◽  
Stillborn Fetus ◽  
Hepatocellular Adenomas

Rarely, liver tissue can be seen in the umbilical cord, where it is thought to result from ectopic localization during embryogenesis. The placental parenchyma is also a rare site for this occurrence. The exact pathophysiology of ectopic liver in the placenta is unknown. It has been considered that aberrant migration or displacement of cells from the developing hepatic buds leads to ectopic liver formation, including groups of liver cells that become entrapped in the foregut as the diaphragm closes. Additional hypotheses put forward have included monodermal teratoma and hepatocellular adenoma. While the lesions may not actually be adenomas, this term has been most utilized in the literature. Hepatocellular adenomas of the placenta are extremely rare; only 9 cases have been reported thus far. We report an additional occurrence of ectopic liver in the placenta, which is the only one reported in a stillborn, and review the literature.

scholarly journals Ectopic liver tissue in umbilical cord

2011 ◽  
Vol 57 (3) ◽  
pp. 229 ◽  
Author(s):  
P Vaideeswar ◽  
R Nanavati ◽  
D Yewatkar ◽  
P Bhuiyan
Keyword(s):  
Umbilical Cord ◽  
Liver Tissue ◽  
Ectopic Liver

Ectopic liver tissue within the umbilical cord

2001 ◽  
Vol 36 (7) ◽  
pp. 1085-1086 ◽  
Author(s):  
Aviya Preminger ◽  
Raphael Udassin ◽  
Orit Pappo ◽  
Ilan Arad
Keyword(s):  
Umbilical Cord ◽  
Liver Tissue ◽  
Ectopic Liver

Ectopic liver within the umbilical cord in a very preterm infant from a multiple gestation

2011 ◽  
pp. 110428110516006
Author(s):  
Victor Javier Lara-Díaz ◽  
Raul Garza-Bulnes ◽  
Raul Garza-Garza ◽  
Manuel Durand
Keyword(s):  
Preterm Infant ◽  
Umbilical Cord ◽  
Multiple Gestation ◽  
Very Preterm ◽  
Very Preterm Infant ◽  
Ectopic Liver

scholarly journals CHANGES OF 8-OXO-2'-DEOXYGUANOSINE LEVEL IN MOUSE LIVER CELLS DNA IN CASE OF ACUTE TOXIC STRESS

2016 ◽  
Vol 11 (6) ◽  
pp. 68-74
Author(s):  
N. V. Marmiy ◽  
D. S. Esipov
Keyword(s):  
Carbon Tetrachloride ◽  
Liver Tissue ◽  
Mouse Liver ◽  
Pathological Change ◽  
Liver Cells ◽  
Antioxidant Systems ◽  
Toxic Stress ◽  
Laboratory Mice ◽  
Short Term ◽  
Initial Injection

The changes of the 8-oxo-2'-deoxyguanosine (8-oxo-dG)/dG ratio in the DNA of laboratory mice hepatocytes under the influence of toxic stress were studied. It was shown that the injection of carbon tetrachloride causes the growth of 8-oxo-dG level. A rapid increase in the level of 8-oxo-dG in DNA occurs during the first day of the experiment at short-term toxic stress. Subsequently, 48 hours after the initial injection, the level of 8-oxo-dG decreases to the control values. This change in the value of the biomarker can be attributed to the activation of the reparative and antioxidant systems. The subsequent injection results again in an increase of 8-oxo-dG level, and the latter only increases thereafter. This reflects the exhaustion of the reparative potential of the organism and accompanies the progress of inflammation and pathological change of the liver tissue.

scholarly journals A Preliminary Study on the Effect of Hydrogen Gas on Alleviating Early CCl4-Induced Chronic Liver Injury in Rats

Antioxidants ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 1933
Author(s):  
Jianwei Wang ◽  
Quancheng Cheng ◽  
Jinyu Fang ◽  
Huiru Ding ◽  
Huaicun Liu ◽  
...  
Keyword(s):  
Liver Injury ◽  
Liver Tissue ◽  
Uncoupling Protein ◽  
Liver Cells ◽  
Hydrogen Gas ◽  
Chronic Liver ◽  
Control Group ◽  
Protective Mechanism ◽  
Chronic Liver Injury ◽  
Ucp2 Expression

As a small-molecule reductant substance, hydrogen gas has an obvious antioxidant function. It can selectively neutralize hydroxyl radicals (•OH) and peroxynitrite (ONOO•) in cells, reducing oxidative stress damage. The purpose of this study was to investigate the effect of hydrogen gas (3%) on early chronic liver injury (CLI) induced by CCl4 and to preliminarily explore the protective mechanism of hydrogen gas on hepatocytes by observing the expression of uncoupling protein 2 (UCP2) in liver tissue. Here, 32 rats were divided into four groups: the control group, CCl4 group, H2 (hydrogen gas) group, and CCl4 + H2 group. The effect of hydrogen gas on early CLI was observed by serological tests, ELISA, hematoxylin and eosin staining, and oil red O staining. Immunohistochemical staining and Western blotting were used to observe the expression of UCP2 in liver tissues. We found that CCl4 can induce significant steatosis in hepatocytes. When the hydrogen gas was inhaled, hepatocyte steatosis was reduced, and the UCP2 expression level in liver tissue was increased. These results suggest that hydrogen gas might upregulate UCP2 expression levels, reduce the generation of intracellular oxygen free radicals, affect lipid metabolism in liver cells, and play a protective role in liver cells.

scholarly journals Transcriptional Regulation of the TFIIH Transcription Repair Components XPB and XPD by the Hepatitis B Virus x Protein in Liver Cells and Transgenic Liver Tissue

2001 ◽  
Vol 276 (17) ◽  
pp. 14124-14132 ◽  
Author(s):  
Iris Jaitovich-Groisman ◽  
Naciba Benlimame ◽  
Betty L. Slagle ◽  
Maite Hernandez Perez ◽  
Lesley Alpert ◽  
...  
Keyword(s):  
Transcriptional Regulation ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Liver Tissue ◽  
Liver Cells ◽  
X Protein ◽  
B Virus

Regression of multiple hepatocellular adenomas after cessation of oral contraceptive pills : a case report and review of the current literature

2021 ◽  
Vol 84 (3) ◽  
Author(s):  
G Moors ◽  
H Poels ◽  
V Vandecaveye ◽  
T Roskams ◽  
C Verslype
Keyword(s):  
Current Literature ◽  
Hepatocellular Adenoma ◽  
Liver Neoplasm ◽  
Resonance Imaging ◽  
Natural Evolution ◽  
Oral Contraceptive Pills ◽  
Contraceptive Pills ◽  
Magnetic Resonance Imaging Mri ◽  
Benign Liver ◽  
Hepatocellular Adenomas

Hepatocellular adenoma (HCA) is an uncommon benign liver neoplasm usually solitary and identified incidentally on imaging. We report a case of a 50-year old female who was diagnosed with multiple hepatic adenomas of the inflammatory subtype. After discontinuation of oral contraception a decrease of both the number and size of the liver lesions was seen on magnetic resonance imaging (MRI) without the need of further intervention. The major challenge in the clinical management of patients with multiple HCAs resides in the risk assessment for future complications. In the case of multiple HCAs subtype seemed to be more relevant than the actual number of lesions. Because little is known about the natural evolution in patients with multiple HCAs, we performed a review of the current literature with focus on the different subtypes and their clinical relevance.

scholarly journals THE RELATION OF SERUM ESTERASE TO LIVER DESTRUCTION

1915 ◽  
Vol 22 (6) ◽  
pp. 707-712 ◽  
Author(s):  
James W. Jobling ◽  
A. A. Eggstein ◽  
William Petersen
Keyword(s):  
Hepatic Vein ◽  
Esterase Activity ◽  
Liver Tissue ◽  
Fatty Degeneration ◽  
Liver Cells

1. Liver tissue showing fatty degeneration obtained from animals poisoned with phosphorus or chloroform contains a decreased amount of esterase. 2. The serum of animals poisoned with phosphorus or chloroform has a high esterase activity. 3. The increased amount of esterase in the serum is not derived from the disintegrating liver cells as the esterase in the blood of the hepatic vein is less than that found elsewhere.

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