Endophthalmitis after dropless (Tri-Moxi injection) cataract surgery

2019 ◽  
Vol 30 (5) ◽  
pp. NP29-NP31 ◽  
Author(s):  
Caleb Ng ◽  
Kakarla V Chalam
Keyword(s):  
Cataract Surgery ◽  
Staphylococcus Epidermidis ◽  
Vision Loss ◽  
Hand Motion ◽  
Corrected Visual Acuity ◽  
Case Summary ◽  
Keratic Precipitates ◽  
Vitreous Sample ◽  
Severe Vision Loss ◽  
Pars Plana

Introduction: A case of endophthalmitis after dropless cataract surgery with intravitreal Tri-Moxi associated with severe vision loss. Case summary: An 82-year-old male developed severe vision loss in the left eye 24 days after dropless cataract surgery with intravitreal Tri-Moxi injection. Best corrected visual acuity was hand motion in the left eye. Intraocular pressure was 13, with inferior keratic precipitates, 4 + cell with 1 mm layered hypopyon, and a plaque on the posterior capsule that blocked direct exam of the posterior segment. Ultrasonography revealed extensive vitritis without retinal or choroidal detachments. Conclusion: Endophthalmitis resolved and vision improved after management with vitreous tap, intravitreal and fortified topical antibiotics, and subsequent prompt pars plana vitrectomy. Vitreous sample grew fluoroquinolone-resistant staphylococcus epidermidis.

scholarly journals Repair of Traumatic Rhegmatogenous Retinal Detachment Combined with Congenital Falciform Retinal Detachment

2018 ◽  
Vol 9 (1) ◽  
pp. 55-59
Author(s):  
Fukutaro Mano ◽  
Kuo-Chung Chang ◽  
Tomiya Mano
Keyword(s):  
Retinal Detachment ◽  
Patient Outcomes ◽  
Rhegmatogenous Retinal Detachment ◽  
Scleral Buckling ◽  
Retrospective Case ◽  
Hand Motion ◽  
Corrected Visual Acuity ◽  
Pars Plana Lensectomy ◽  
Pars Plana

Purpose: To report a case of surgical repair of traumatic rhegmatogenous retinal detachment combined with congenital falciform retinal detachment (FRD). Methods: A retrospective case report. Results: A 36-year-old man with traumatic rhegmatogenous retinal detachment complicating a previously known FRD was successfully treated despite residual FRD following pars plana lensectomy, vitrectomy, and encircling scleral buckling. His best corrected visual acuity improved from hand motion at 50 cm to 20/1,000. Conclusion: We concluded that the root of the FRD is susceptible to trauma because of the contraction of fibrovascular tissue. The early intervention of modern vitrectomy to traumatic rhegmatogenous retinal detachment complicating a previously known FRD is an important consideration for enhanced quality of care and optimal patient outcomes.

scholarly journals Endophthalmitis following 27-Gauge Pars Plana Vitrectomy for Vitreous Floaters

2016 ◽  
Vol 7 (3) ◽  
pp. 523-528 ◽  
Author(s):  
Zhong Lin ◽  
Rong Han Wu ◽  
Nived Moonasar
Keyword(s):  
Staphylococcus Epidermidis ◽  
Pars Plana Vitrectomy ◽  
Surgical Intervention ◽  
Silicone Oil ◽  
Clinical Course ◽  
Oil Removal ◽  
Corrected Visual Acuity ◽  
Vitreous Floaters ◽  
Pars Plana ◽  
Oil Injection

Purpose: To report a case of Staphylococcus epidermidis endophthalmitis following 27-gauge pars plana vitrectomy for symptomatic vitreous floaters. Methods: The clinical course and imaging findings, including fundus optomap, and spectral domain optical coherence tomography of a 24-year-old male patient were documented. Results: The patient, with a preoperative best-corrected visual acuity (BCVA) of 1.0, developed endophthalmitis following 27-gauge pars plana vitrectomy for symptomatic vitreous floaters. After a series of treatments, including emergent vitreous tap and silicone oil injection, antibiotic treatment, and silicone oil removal, the patient regained a BCVA of 0.6. Conclusion: Although rare, the potential risk of endophthalmitis should be explicitly discussed with patients considering surgical intervention for vitreous floaters.

scholarly journals A Rare Case of Lens-Induced Uveitis with Proliferative Vitreoretinopathy and Massive Encapsulation of Fallen Nuclear Material

2020 ◽  
Vol 11 (2) ◽  
pp. 436-441
Author(s):  
Saki Inoue ◽  
Hisanori Imai ◽  
Akira Tetsumoto ◽  
Keiko Otsuka ◽  
Makoto Nakamura
Keyword(s):  
Cataract Surgery ◽  
Proliferative Vitreoretinopathy ◽  
Rare Case ◽  
Vision Loss ◽  
Nuclear Material ◽  
Oral Steroid ◽  
Vitreous Opacity ◽  
Complicated Cataract ◽  
Pars Plana ◽  
The Right

We experienced a rare case of lens-induced uveitis (LIU) with severe proliferative vitreoretinopathy (PVR) diagnosed upon finding lens nuclear material encapsulated by intravitreal proliferative tissue. A 60-year-old man was referred to our hospital for the treatment of vision loss caused by unexplained uveitis in the right eye (OD). Seven months previously, a complicated cataract surgery that required unplanned anterior vitrectomy and transscleral suture of intraocular lens was performed on that eye at another clinic. Severe inflammation with dense vitreous opacity occurred in the OD postoperatively. Although topical and oral administration of steroids reduced the inflammation 7 months after the surgery, PVR with tractional retinal detachment was developed in the OD. Pars plana vitrectomy (PPV) was performed for the treatment and diagnosis. PPV revealed the presence of lens nuclear fragments within the vitreous, which was approximately 60% the ordinary nucleus size and was encapsulated by intravitreal proliferative tissue. The nuclear fragments were extracted from a superior corneoscleral flap. Intraocular inflammation was reduced with postoperative topical and oral steroid treatments and the retina remained reattached 1 year after the PPV. In conclusion, uveitis with an episode of a complicated cataract surgery may suggest LIU.

scholarly journals Pseudomonas aeruginosa endophthalmitis caused by accidental iatrogenic ocular injury with a hypodermic needle

2017 ◽  
Vol 45 (2) ◽  
pp. 882-885
Author(s):  
Cheng-wei Lu ◽  
Ji-long Hao ◽  
Xiu-fen Liu ◽  
Ling-ling Liang ◽  
Dan-dan Zhou
Keyword(s):  
Vision Loss ◽  
Hypodermic Needle ◽  
Ocular Infection ◽  
Ocular Injury ◽  
Antibiotic Administration ◽  
Hand Motion ◽  
Severe Vision Loss ◽  
The Right ◽  
Type Of Injury

Iatrogenic traumatic endophthalmitis is a rare but serious ocular infection that can lead to severe vision loss. A 44-year-old man presented with pain and decreased vision in the right eye 4 hours after injury with a hypodermic needle during irrigation of his eye. Slit-lamp examination revealed a penetrating corneal puncture and iris hole in the right eye. Twenty hours later, his visual acuity had decreased to hand motion, and severe fibrinoid uveitis was noted. He immediately underwent irrigation of the anterior chamber and intravitreal antibiotic injection. The right eye became painful again, and emergent vitrectomy combined with lensectomy was performed along with intravitreal antibiotic administration. The patient remained stable during the 2-month follow-up. Standard practice should be adopted when irrigating the eye to prevent this type of injury, and emergent surgical intervention is very important to preserve visual function.

Vision loss in a pregnant woman with nephrotic syndrome

2021 ◽  
pp. 112067212110547
Author(s):  
Zoi Tsani ◽  
Antonios Ntafos ◽  
Victoria Toumanidou ◽  
Anna Dastiridou ◽  
Ioanna Ploumi ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Nephrotic Syndrome ◽  
Pregnant Woman ◽  
Vision Loss ◽  
Pigment Epithelium ◽  
Hand Motion ◽  
Corrected Visual Acuity ◽  
Visual Acuity Loss ◽  
The Right

Purpose To report acute visual acuity loss in a pregnant woman with nephrotic syndrome. Case Report A 34-year-old pregnant woman was referred to our service for acute, bilateral visual impairment, associated with bilateral below knee edema (BKE). Best-corrected visual acuity (BCVA) was hand motion in the right eye and 20/200 in the left eye. Dilated fundus exam disclosed multiple pigment epithelium detachments involving the macula in both eyes. After consultation with a nephrologist a diagnosis of nephrotic syndrome was made. Unfortunately, a week later she lost the fetus. At follow-up evaluation, 20 days after the miscarriage, BCVA improved to 20/25 in both eyes with near normal restoration of the retinal anatomy. Conclusion In nephrotic syndrome, sequestration of interstitial fluids, which leads to classic generalized edema, could be the origin of interstitial accumulation of fluids in the retinal and subretinal layers. Increased awareness by the gynaecologists and prompt treatment may prevent fetus miscarriage.

scholarly journals Paracentral acute middle maculopathy as a finding in patients with severe vision loss following phacoemulsification cataract surgery

2017 ◽  
Vol 45 (6) ◽  
pp. 598-605 ◽  
Author(s):  
Katarina Creese ◽  
Daini Ong ◽  
Sukhpal S Sandhu ◽  
David Ware ◽  
C Alex Harper ◽  
...  
Keyword(s):  
Cataract Surgery ◽  
Vision Loss ◽  
Severe Vision Loss ◽  
Phacoemulsification Cataract Surgery

Vitrectomy for Symptomatic Asteroid Hyalosis

2021 ◽  
pp. 247412642199860
Author(s):  
Elizabeth Marlow ◽  
Tarek Hassan ◽  
Lisa Faia ◽  
Kimberly Drenser ◽  
Bruce Garretson
Keyword(s):  
Visual Acuity ◽  
Pars Plana Vitrectomy ◽  
Vision Loss ◽  
Acute Onset ◽  
Average Decrease ◽  
Asteroid Hyalosis ◽  
Severe Vision Loss ◽  
Pars Plana

Purpose: Acute vision loss may accompany complete or partial posterior vitreous separation in asteroid hyalosis (AH), and pars plana vitrectomy may resolve these symptoms. Methods: Six individuals with AH and acute vision loss associated with diagnosed posterior vitreous separation were treated with pars plana vitrectomy, and visual acuity (VA) recovery was monitored for 3 months. Results: The study patients’ preoperative VA ranged from 20/25 to 20/2500 (mean, 20/150; logMAR, 0.88). The average decrease in VA with anterior progression of the hyaloid was logMAR 0.70. Following surgical clearance of the asteroid bodies, VA returned to baseline within 1 month following vitrectomy in 2 eyes, and within 3 months in all eyes. Final VA was 20/20 to 20/200 (mean, 20/35; logMAR, 0.24). Conclusions: Patients with AH may present with acute onset of severe vision loss in association with posterior vitreous separation. Vitrectomy may be curative and restore vision.

The Level of Cytokines in the Vitreous Body of Severe Proliferative Diabetic Retinopathy Patients Undergoing Posterior Vitrectomy

2018 ◽  
Vol 24 (27) ◽  
pp. 3276-3281 ◽  
Author(s):  
Dorota Raczyńska ◽  
Katarzyna A. Lisowska ◽  
Krzysztof Pietruczuk ◽  
Joanna Borucka ◽  
Mateusz Ślizień ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
Proliferative Diabetic Retinopathy ◽  
Vitreous Body ◽  
Control Group ◽  
Slit Lamp ◽  
Corrected Visual Acuity ◽  
Cytokine Levels ◽  
Pars Plana ◽  
Eye Examination

Objective: The objective of the study was to compare cytokine levels in the vitreous body of patients with proliferative diabetic retinopathy (PDR) undergoing posterior vitrectomy. Patients and methods: The study included 39 patients (39 eyes) undergoing pars plana vitrectomy (PPV). Patients were divided into three groups: patients with proliferative diabetic retinopathy (PDR) without aflibercept injection prior to the surgery, PDR patients administered aflibercept injection prior to the surgery, and patients without diabetes mellitus (control group). All patients underwent a comprehensive eye examination one day before and 3 weeks after the surgery, including measurements of: best-corrected visual acuity (BVCA) and intraocular pressure (IOP), slit-lamp examination and spectral domain optical coherence tomography (SOCT). Concentrations of cytokines: IL-6, IL-8, IL-12p70, TNF, IL-10, IL-1β were measured in the vitreous body of patients with BD™ Cytometric Bead Array (CBA) Human Inflammatory Cytokines Kit. Results: PDR patients who received pretreatment with aflibercept injection showed significantly lower concentrations of IL-12p70, TNF, IL-10 and IL-1β in the vitreous body compared to the control group. Meanwhile, patients without prior aflibercept injection had a significantly higher concentration of IL-8. There was also a significant positive correlation between IOP before PPV and IL-8 concentration in both PDR patients’ groups. Conclusion: Findings of our study suggest an important role of IL-8 in the development of severe PDR. Aflibercept administration on the day before elective vitrectomy facilitated the surgery.

scholarly journals Nanogel-Facilitated In-Situ Delivery of a Cataract Inhibitor

Biomolecules ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1150
Author(s):  
Dixa Gautam ◽  
Michelle G. Pedler ◽  
Devatha P. Nair ◽  
Jonathan Mark Petrash
Keyword(s):  
Cataract Surgery ◽  
Vision Loss ◽  
Effective Means ◽  
Lens Capsule ◽  
Posterior Capsular Opacification ◽  
Surgical Removal ◽  
Visual Disability ◽  
Visual Axis ◽  
Number Of Patients ◽  
Subsequent Degradation

Cataracts are a leading cause of blindness worldwide. Surgical removal of cataracts is a safe and effective procedure to restore vision. However, a large number of patients later develop vision loss due to regrowth of lens cells and subsequent degradation of the visual axis leading to visual disability. This postsurgical complication, known as posterior capsular opacification (PCO), occurs in up to 30% of cataract patients and has no clinically proven pharmacological means of prevention. Despite the availability of many compounds capable of preventing early steps in PCO development, there is currently no effective means to deliver such therapies into the eye for a suitable duration. To model a solution to this unmet medical need, we fabricated acrylic substrates as intraocular lens (IOL) mimics scaled to place into the capsular bag of the mouse lens following a mock-cataract surgery. Substrates were coated with a hydrophilic crosslinked acrylate nanogel designed to elute Sorbinil, an aldose reductase inhibitor previously shown to suppress PCO. Insertion of the Sorbinil-eluting device into the lens capsule at the time of cataract surgery resulted in substantial prevention of cellular changes associated with PCO development. This model demonstrates that a cataract inhibitor can be delivered into the postsurgical lens capsule at therapeutic levels.

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