Color Doppler Imaging of the Retrobulbar Circulation in Age-Related Macular Degeneration

1998 ◽  
Vol 8 (4) ◽  
pp. 234-238 ◽  
Author(s):  
B.M. Hosal ◽  
G. Karakoç ◽  
E. GÜrsel ◽  
M. Çamur

Purpose The aim of this study was to assess hemodynamic changes in the retrobulbar circulation in patients with age-related macular degeneration (ARMD). Methods Color Doppler imaging was used to calculate blood flow velocities and vascular resistance of the central retinal artery, short posterior ciliary artery and ophthalmic artery in patients with ARMD and in control patients. Results The average peak systolic velocity was significantly lower in the central retinal artery (p < 0.001), posterior ciliary artery (p < 0.001) and ophthalmic artery (p < 0.01) of the patients with ARMD than in control. End-diastolic blood flow velocities in the retrobulbar arteries of ARMD patients were also significantly lower (p < 0.001) than controls. Gosling's pulsatility index was significantly higher in the ophthalmic artery (p<0.01) and posterior ciliary artery (p < 0.001) of eyes with ARMD. In addition, the resistivity index was significantly higher in all retrobulbar arteries (p < 0.001) of these patients. Conclusions The hemodynamic abnormalities in the retrobulbar circulation suggest that vascular impairment may play a role in the pathogenesis of ARMD.

2021 ◽  
Vol 18 (2) ◽  
Author(s):  
Marzieh Soleimani ◽  
Seyed Ehsan Ghetmiri ◽  
Mohammad Hossein Ahrar Yazdi

Background: Color Doppler imaging (CDI) is a non-aggressive and safe technique for the clinical management of retinal diseases. Recently, the number of infants with retinopathy of prematurity (ROP) has increased due to the incidence of premature births. Objectives: This study aimed to compare the CDI criteria for the ophthalmic artery (OA) and central retinal artery (CRA) in ROP infants with and without plus disease. Patients and Methods: In this case-control study, 42 premature infants (21 infants with plus disease and 21 infants without plus disease) underwent CDI. The arterial CDI parameters, including end-diastolic velocity (EDV), pulsatility index (PI), resistance index (RI), and peak systolic velocity (PSV), were measured in these patients. After collecting the data, t-test and chi-square tests were used for data analysis. P < 0.05 was considered to be statistically significant. Results: The mean EDV of CRA in patients with and without plus disease was 4.35 ± 1.00 and 5.27 ± 1.02 cm/sec, respectively (P = 0.005). The mean PSV of CRA in patients with and without plus disease was 15.65 ± 3.35 and 18.39 ± 4.39 cm/sec, respectively (P = 0.029). However, no significant difference was found between the two groups in terms of PSV or EDV of OA (P > 0.05). Also, no significant difference was observed between the two groups considering the RI and PI of CRA and OA (P > 0.05). Conclusion: According to the findings of this study, CDI criteria, such as EDV and PSV of CRA, were significantly lower in infants with plus disease as compared to those without plus disease. Since detecting the early stages of plus disease is a challenge for ophthalmologists, assessment of these criteria can be helpful for differentiation of these two subgroups of patients. However, further studies with a larger sample size are needed to determine the cutoff value.


2018 ◽  
Vol 66 (1) ◽  
pp. 89 ◽  
Author(s):  
DavidP Piñero ◽  
Fermin Rodrigo ◽  
JoséMaría Ruiz-Moreno ◽  
JuanBernabé García ◽  
MaríaEugenia Torregrosa ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Shin Takayama ◽  
Masashi Watanabe ◽  
Hiroko Kusuyama ◽  
Satoru Nagase ◽  
Takashi Seki ◽  
...  

Color Doppler imaging (CDI) can be used to noninvasively create images of human blood vessels and quantitatively evaluate blood flow in real-time. The purpose of this study was to assess the effects of acupuncture on the blood flow of the peripheral, mesenteric, and retrobulbar arteries by CDI. Statistical significance was defined asPvalues less than 0.05. Blood flow in the radial and brachial arteries was significantly lower during needle stimulation on LR3 than before in healthy volunteers, but was significantly higher after needle stimulation than before. LR3 stimulation also resulted in a significant decrease in the vascular resistance of the short posterior ciliary artery and no significant change of blood flow through the superior mesenteric artery (SMA) during acupuncture. In contrast, ST36 stimulation resulted in a significant increase in blood flow through the SMA and no significant change in the vascular resistance of the retrobulbar arteries. Additionally, acupuncture at previously determined acupoints in patients with open-angle glaucoma led to a significant reduction in the vascular resistance of the central retinal artery and short posterior ciliary artery. Our results suggest that acupuncture can affect blood flow of the peripheral, mesenteric, and retrobulbar arteries, and CDI can be useful to evaluate hemodynamic changes by acupuncture.


2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Fatima Jimenez-Aragon ◽  
Elena Garcia-Martin ◽  
Raquel Larrosa-Lopez ◽  
Jose M. Artigas-Martín ◽  
Pilar Seral-Moral ◽  
...  

This longitudinal and prospective study analyzes the ability of orbital blood flow measured by color Doppler imaging (CDI) to predict glaucoma progression in patients with glaucoma risk factors. Patients with normal perimetry but having glaucoma risk factors and patients in the initial phase of glaucoma were prospectively included in the study and divided, after a five-year follow-up, into two groups: “Progression” and “No Progression” based on the changes in the Moorfields regression analysis (MRA) classification of Heidelberg retina tomograph (HRT). An orbital CDI was performed in all patients and the parameters obtained were correlated with changes in HRT. A logistic discrimination function (LDF) was calculated for ophthalmic artery (OA) and central retinal artery (CRA) parameters. Receiver operating characteristics curves (ROC) were used to assess the usefulness of LDFs to predict glaucomatous progression. A total of 71 eyes were included. End-diastolic velocity, time-averaged velocity, and resistive index in the OA and CRA were significantly different (P<0.05) between the Progression and No Progression groups. The area under the ROC curves calculated for both LDFs was of 0.695 (OA) and 0.624 (CRA). More studies are needed to evaluate the ability of CDI to perform early diagnosis and to predict progression in glaucoma in eyes.


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