scholarly journals Effects of anti-glaucoma drugs on resistive index of the medial long posterior ciliary artery using color Doppler imaging in Beagle dogs

2011 ◽  
Vol 12 (1) ◽  
pp. 99 ◽  
Author(s):  
Hojung Choi ◽  
Youngwon Lee ◽  
Seongchan Yeon ◽  
Hyojong Lee ◽  
Heechun Lee
2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Shin Takayama ◽  
Takashi Seki ◽  
Toru Nakazawa ◽  
Naoko Aizawa ◽  
Seri Takahashi ◽  
...  

Background. The relation between glaucoma and retrobulbar circulation in the prognosis has been indicated.Purpose. To investigate the effects of acupuncture on retrobulbar circulation in open-angle glaucoma (OAG) patients.Methods. Eleven OAG patients (20 eyes with OAG) who were treated by topical antiglaucoma medications for at least 3 months were enrolled. Acupuncture was performed once at acupoints BL2, M-HN9, ST2, ST36, SP6, KI3, LR3, GB20, BL18, and BL23 bilaterally. Retrobulbar circulation was measured with color Doppler imaging, and intraocular pressure (IOP) was also measured at rest and one hour after rest or before and after acupuncture.Results. TheΔvalue of the resistive index in the short posterior ciliary artery (P<.01) and theΔvalue of IOP (P<.01) were decreased significantly by acupuncture compared with no acupuncture treatment.Conclusions. Acupuncture can improve the retrobulbar circulation and IOP, which may indicate the efficacy of acupuncture for OAG.


1998 ◽  
Vol 8 (4) ◽  
pp. 234-238 ◽  
Author(s):  
B.M. Hosal ◽  
G. Karakoç ◽  
E. GÜrsel ◽  
M. Çamur

Purpose The aim of this study was to assess hemodynamic changes in the retrobulbar circulation in patients with age-related macular degeneration (ARMD). Methods Color Doppler imaging was used to calculate blood flow velocities and vascular resistance of the central retinal artery, short posterior ciliary artery and ophthalmic artery in patients with ARMD and in control patients. Results The average peak systolic velocity was significantly lower in the central retinal artery (p < 0.001), posterior ciliary artery (p < 0.001) and ophthalmic artery (p < 0.01) of the patients with ARMD than in control. End-diastolic blood flow velocities in the retrobulbar arteries of ARMD patients were also significantly lower (p < 0.001) than controls. Gosling's pulsatility index was significantly higher in the ophthalmic artery (p<0.01) and posterior ciliary artery (p < 0.001) of eyes with ARMD. In addition, the resistivity index was significantly higher in all retrobulbar arteries (p < 0.001) of these patients. Conclusions The hemodynamic abnormalities in the retrobulbar circulation suggest that vascular impairment may play a role in the pathogenesis of ARMD.


2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Shin Takayama ◽  
Masashi Watanabe ◽  
Hiroko Kusuyama ◽  
Satoru Nagase ◽  
Takashi Seki ◽  
...  

Color Doppler imaging (CDI) can be used to noninvasively create images of human blood vessels and quantitatively evaluate blood flow in real-time. The purpose of this study was to assess the effects of acupuncture on the blood flow of the peripheral, mesenteric, and retrobulbar arteries by CDI. Statistical significance was defined asPvalues less than 0.05. Blood flow in the radial and brachial arteries was significantly lower during needle stimulation on LR3 than before in healthy volunteers, but was significantly higher after needle stimulation than before. LR3 stimulation also resulted in a significant decrease in the vascular resistance of the short posterior ciliary artery and no significant change of blood flow through the superior mesenteric artery (SMA) during acupuncture. In contrast, ST36 stimulation resulted in a significant increase in blood flow through the SMA and no significant change in the vascular resistance of the retrobulbar arteries. Additionally, acupuncture at previously determined acupoints in patients with open-angle glaucoma led to a significant reduction in the vascular resistance of the central retinal artery and short posterior ciliary artery. Our results suggest that acupuncture can affect blood flow of the peripheral, mesenteric, and retrobulbar arteries, and CDI can be useful to evaluate hemodynamic changes by acupuncture.


2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Fatima Jimenez-Aragon ◽  
Elena Garcia-Martin ◽  
Raquel Larrosa-Lopez ◽  
Jose M. Artigas-Martín ◽  
Pilar Seral-Moral ◽  
...  

This longitudinal and prospective study analyzes the ability of orbital blood flow measured by color Doppler imaging (CDI) to predict glaucoma progression in patients with glaucoma risk factors. Patients with normal perimetry but having glaucoma risk factors and patients in the initial phase of glaucoma were prospectively included in the study and divided, after a five-year follow-up, into two groups: “Progression” and “No Progression” based on the changes in the Moorfields regression analysis (MRA) classification of Heidelberg retina tomograph (HRT). An orbital CDI was performed in all patients and the parameters obtained were correlated with changes in HRT. A logistic discrimination function (LDF) was calculated for ophthalmic artery (OA) and central retinal artery (CRA) parameters. Receiver operating characteristics curves (ROC) were used to assess the usefulness of LDFs to predict glaucomatous progression. A total of 71 eyes were included. End-diastolic velocity, time-averaged velocity, and resistive index in the OA and CRA were significantly different (P<0.05) between the Progression and No Progression groups. The area under the ROC curves calculated for both LDFs was of 0.695 (OA) and 0.624 (CRA). More studies are needed to evaluate the ability of CDI to perform early diagnosis and to predict progression in glaucoma in eyes.


Renal Failure ◽  
2012 ◽  
Vol 34 (6) ◽  
pp. 708-712 ◽  
Author(s):  
Taner Basturk ◽  
Ramazan Albayrak ◽  
Turgay Ulas ◽  
Mehmet Akcay ◽  
Abdulkadir Unsal ◽  
...  

2014 ◽  
Vol 62 (6) ◽  
pp. 671 ◽  
Author(s):  
Ali Akal ◽  
Tugba Goncu ◽  
Ekrem Karakas ◽  
FatimaNurefsan Boyaci ◽  
Abdulgafur Bata ◽  
...  

2001 ◽  
Vol 280 (4) ◽  
pp. H1442-H1447 ◽  
Author(s):  
Elzbieta Polska ◽  
Karl Kircher ◽  
Paulina Ehrlich ◽  
Pia V. Vecsei ◽  
Leopold Schmetterer

The aim of the present study was to investigate the association between ultrasound Doppler measurements of resistive index (RI) in the central retinal artery and retinal vascular resistance ( R) assessed with laser Doppler velocimetry, vessel size measurement, and calculation of ocular perfusion pressure (PP) in healthy subjects. An increase in vascular resistance was induced by inhalation of 100% O2. During hyperoxia no significant changes in PP were observed. Mean flow velocity in main retinal veins was reduced by −27.5 ± 2.0%. The average decrease in diameter was −11.5 ± 1.0%. R, which was calculated as the ratio of PP to flow rate, increased by 97.6 ± 7.7%. RI increased as well, but the effect was much smaller (6.6 ± 2.2%). In addition, a negative correlation was found between baseline values of R and RI ( r = −0.83). During hyperoxia R and RI were not associated. In conclusion, our data indicate that RI as assessed with color Doppler imaging in the central retinal artery is not an adequate measure of R.


2021 ◽  
Vol 9 ◽  
Author(s):  
George Koshy Parapatt ◽  
Teresa Oranges ◽  
Guglielmo Paolantonio ◽  
Lucilla Ravà ◽  
Simona Giancristoforo ◽  
...  

Infantile hemangioma (IH) is the most common benign vascular tumor in childhood. In more than 85% of all cases, IHs undergo spontaneous involution, but nearly 10–12% of IHs develop complications and require immediate therapy. Oral propranolol is currently the first-line treatment for IHs. Color Doppler ultrasound is the gold standard in the diagnosis of deep IH, and it is used to evaluate the morphological change and the modification of vascularization that occur during its evolution and treatment. To date, only few data in the literature described the changes of intralesional arterial resistive index (RI) during treatment with propranolol; particularly, some authors have shown an increase of intralesional arterial RI in IHs with clinical regression during treatment with propranolol. The objective of this paper is to evaluate the changes of RI of the intralesional arteries of the IHs during the treatment with oral propranolol. We retrospectively analyzed a total of 64 IHs in 60 patients treated with oral propranolol with a good clinical response. Gray-scale ultrasonography and color Doppler imaging were performed before and during the therapy. The intralesional RIs were measured before and during the treatment. For each lesion, we recorded the RI values, and then we calculated the mean RI value for any single lesion. We compared the mean RI value observed at the baseline with the mean RI value of the last detectable sampling at color Doppler. We also compared between them the mean RI values observed during intermediate ultrasound. The RI values were compared in 44 lesions, with at least two significant samplings of RI. In the 44 lesions compared, we did not find statistically significant variations in the mean RI values between the baseline control and the values recorded at the last post-treatment control. The time trend of mean RI values of the intermediate color Doppler analysis performed between the first pre-treatment control and the last measurable control did not show any statistically significant variation in the trend of mean RI values. Contrarily to what has been described by some authors, in our experience, we have not observed an increase of RI in IHs treated with oral propranolol.


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