scholarly journals Unique relations between post-traumatic stress disorder symptoms and patient functioning in type 2 diabetes

2017 ◽  
Vol 25 (5) ◽  
pp. 652-664
Author(s):  
Danielle Arigo ◽  
Vanessa Juth ◽  
Paula Trief ◽  
Kenneth Wallston ◽  
Jan Ulbrecht ◽  
...  

This study examined reported post-traumatic stress disorder symptoms in adults with poorly controlled type 2 diabetes who had no history of psychiatric diagnosis or treatment ( n = 184, MHbA1c = 9.13%, standard deviation = 1.68). Participants reported moderate to severe intensity of post-traumatic stress disorder symptoms ( M = 19.17, SD = 17.58). Together, depressive and post-traumatic stress disorder symptoms accounted for 10–40 percent of the variance in type 2 diabetes outcomes; post-traumatic stress disorder symptoms were associated with elevated diabetes distress and more frequent exercise and self-blood glucose testing (unique R2 ~ 3%). Post-traumatic stress disorder symptoms may be overlooked in type 2 diabetes among patients without formal psychiatric diagnoses, and warrant increased attention.

2014 ◽  
Vol 52 (3) ◽  
pp. 513-521 ◽  
Author(s):  
Giacomo Ciocca ◽  
Eleonora Carosa ◽  
Maria Stornelli ◽  
Erika Limoncin ◽  
Giovanni L. Gravina ◽  
...  

Author(s):  
Ryan M. Cassidy ◽  
Ives Cavalcante Passos ◽  
Márcia Kauer-Sant’Anna

Post-traumatic stress disorder (PTSD) has a lifetime prevalence of 10–12% in women and 5–6% in men. Patients with PTSD are at greater risk for obesity, type 2 diabetes mellitus, atherosclerosis, and myocardial infarction. In addition, a subset of these patients develops cognitive impairments unattributable to age or disease comorbidity alone, with hippocampal and prefrontal cortex atrophy. This chapter aims to review the evidence for neuroprogression in PTSD. This concept has been proposed as the pathological rewiring of the brain that takes place in parallel with the clinical and neurocognitive deterioration in the course of some psychiatric disorders. We will also review the biological pathways underlying neuroprogression in PTSD, including changes in inflammatory cytokines, corticosteroids, neurotrophins, and oxidative stress markers.


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