scholarly journals Blockade of the renin-angiotensin system for renal future perspectives protection: from history to future perspective

2007 ◽  
Vol 8 (4) ◽  
pp. 208-211 ◽  
Author(s):  
Michel Burnier
Keyword(s):  
Renin Angiotensin System ◽  
Future Perspective ◽  
Future Perspectives ◽  
Angiotensin System ◽  
Renin Angiotensin

scholarly journals The Prorenin and (Pro)renin Receptor: New Players in the Brain Renin-Angiotensin System?

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Wencheng Li ◽  
Hua Peng ◽  
Dale M. Seth ◽  
Yumei Feng
Keyword(s):  
Renin Angiotensin System ◽  
Ang Ii ◽  
Future Perspectives ◽  
Vasopressin Release ◽  
Angiotensin System ◽  
Renin Angiotensin ◽  
Treatment Of Hypertension ◽  
High Level ◽  
The Brain

It is well known that the brain renin-angiotensin (RAS) system plays an essential role in the development of hypertension, mainly through the modulation of autonomic activities and vasopressin release. However, how the brain synthesizes angiotensin (Ang) II has been a debate for decades, largely due to the low renin activity. This paper first describes the expression of the vasoconstrictive arm of RAS components in the brain as well as their physiological and pathophysiological significance. It then focus on the (pro)renin receptor (PRR), a newly discovered component of the RAS which has a high level in the brain. We review the role of prorenin and PRR in peripheral organs and emphasize the involvement of brain PRR in the pathogenesis of hypertension. Some future perspectives in PRR research are heighted with respect to novel therapeutic target for the treatment of hypertension and other cardiovascular diseases.

Role of genetic variability in the renin-angiotensin system in diabetic and nondiabetic renal disease

2001 ◽  
Vol 21 (6) ◽  
pp. 580-592 ◽  
Author(s):  
Arnold Boonstra ◽  
Dick de Zeeuw ◽  
Paul E. de Jong ◽  
Gerjan Navis
Keyword(s):  
Genetic Variability ◽  
Renal Disease ◽  
Renin Angiotensin System ◽  
Angiotensin System ◽  
Renin Angiotensin

Importance of the Renin-Angiotensin-System in human granulosa lutein cells – RAS in granulosa cells

2008 ◽  
Vol 68 (S 01) ◽  
Author(s):  
D Herr ◽  
WC Duncan ◽  
G Hack ◽  
R Konrad ◽  
R Kreienberg ◽  
...  
Keyword(s):  
Granulosa Cells ◽  
Renin Angiotensin System ◽  
Angiotensin System ◽  
Renin Angiotensin
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