Epidemiology of Opportunistic Infections and Its Correlation With CD4 T-Lymphocyte Counts and Plasma Viral Load Among HIV-Positive Patients at a Tertiary Care Hospital in India

2009 ◽  
Vol 8 (6) ◽  
pp. 333-337 ◽  
Author(s):  
Hitender Gautam ◽  
Preena Bhalla ◽  
Sanjeev Saini ◽  
Beena Uppal ◽  
Ravinder Kaur ◽  
...  
Keyword(s):  
Viral Load ◽  
T Lymphocyte ◽  
Plasma Viral Load ◽  
Opportunistic Infections ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Hiv Positive ◽  
Care Hospital

A study of opportunistic infections in HIV positive patients at a tertiary care hospital at Sangli

2019 ◽  
Vol 10 (1) ◽  
pp. 38-41
Author(s):  
Harshad Adhav ◽  
◽  
Jayshree Awalekar ◽  
Rahul Surve ◽  
Ajinkya Nashte ◽  
...  
Keyword(s):  
Opportunistic Infections ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Hiv Positive ◽  
Care Hospital

scholarly journals A pattern of Opportunistic Infections among HIV In patients on Antiretroviral Therapy in a Tertiary Care Hospital in Coastal Karnataka: A Retrospective Evaluation

2020 ◽  
Vol 11 (4) ◽  
pp. 6385-6390
Author(s):  
Guntur Aishwarya ◽  
Sunil Pai B ◽  
Priyanka Kamath ◽  
Rakesh K B ◽  
Priya Rathi ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Opportunistic Infections ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Hiv Positive ◽  
Care Hospital ◽  
Retrospective Case ◽  
Case Record ◽  
Resource Limited ◽  
Immunodeficiency Virus

Though the incidence of opportunistic infection (OI) is reducing with combination antiretroviral therapy. In this study we aimed to identify the pattern of the occurrence of opportunistic infections in HIV (Human Immunodeficiency Virus) patients. This was a retrospective, case-record based, time-bound study over a four year period (2013-2016) which included HIV positive in-patients aged >18 years of age, of either gender on Antiretroviral Therapy (ART). Demographic details, details of HIV infection including baseline and all available CD4 counts, details of the medications were recorded. Adverse drug reactions (ADR) were recorded by reviewing patient records. Among the files checked, 298 inpatients were on ART regimens recommended by the National AIDS Control Organization (NACO), and were included in the study. Among them, 70.8% of patients developed atleast one OI, 29.8% developed two OIs, and 6.71% developed three OIs. The most common OI was pulmonary tuberculosis (48.3%). The most common ART regimen was a combination of Zidovudine + Lamivudine + Nevirapine. In our study, 70.8% of patients developed at least one OI, which suggests that despite availability of combination ART, OIs continue being a significant issue in patients with HIV in resource-limited settings.

Sero-Prevalence of Parvovirus B 19 Infection Among HIV Positive Patients Attending Tertiary Care Hospital in Central India

2017 ◽  
Vol 01 (04) ◽  
pp. 127-132
Author(s):  
Bhushan Shrikhande ◽  
Meena Mishra ◽  
Mohiuddin Qazi ◽  
Arvind Kurhade ◽  
Chandrashekhar Unakal ◽  
...  
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Central India ◽  
Hiv Positive ◽  
Care Hospital ◽  
Parvovirus B 19

Homelessness among an inpatient HIV-positive cohort at a tertiary care hospital in central London

2020 ◽  
Vol 31 (7) ◽  
pp. 705-707
Author(s):  
Venkateshwaran Sivaraj ◽  
Rudiger Pittrof ◽  
Olubanke Davies ◽  
Ranjababu Kulasegaram
Keyword(s):  
Bacterial Infections ◽  
Substance Misuse ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Hiv Positive ◽  
Care Hospital ◽  
Hiv Viral Load ◽  
Cd4 Cell Count ◽  
Cell Counts ◽  
Cd4 Cell

A cohort review was conducted at a central London tertiary care hospital trust on the prevalence of homelessness among human immunodeficiency virus (HIV)-positive inpatients over a year. Data were collected on the duration of inpatient stay, co-morbidities including acquired immune deficiency syndrome (AIDS)-defining illnesses, co-infections, initiation of antiretroviral therapy, CD4 cell count, HIV viral load and substance misuse. Homeless people were found to be at high risk for hepatitis C, mental health illness, substance misuse including injecting drug use, recurrent bacterial infections, AIDS-associated illnesses, lower CD4 cell counts and HIV viremia. They also had more missed HIV outpatient appointments. It was highlighted that a multidisciplinary approach in their care was necessary to address their needs and reduce the morbidity burden in this cohort.

scholarly journals Prevalence of Human Immunodeficiency Virus in Antenatal Mothers in a Rural Tertiary Care Hospital

2014 ◽  
Vol 6 (3) ◽  
pp. 159-162
Author(s):  
Dhrubajyoti Sarkar ◽  
Banasree Bhadra ◽  
Suvobrata Sarkar ◽  
Biswajit Chakraborty
Keyword(s):  
Human Immunodeficiency Virus ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Rapid Test ◽  
Hiv Positive ◽  
Care Hospital ◽  
Counseling And Testing ◽  
Test Kit ◽  
Immunodeficiency Virus ◽  
Integrated Counseling

ABSTRACT Objective To know the prevalence of human immunodeficiency virus (HIV) among antenatal mothers. Materials and methods It is a retrospective study of antenatal mothers attending the integrated counseling and testing centre (ICTC), College of Medicine and JNM Hospital, Kalyani, from January 2009 to December 2013. Antenatal mothers were counseled and in those willing to undergo test rapid testing was done. First time positive cases were retested two more times by two different companies rapid test kit. The samples were considered as positive when found reactive by all three different methods. Results In our study, a total number of 11343 new antenatal mothers were registered. The pretest counseling could be done for 9437 antenatal mothers. After counseling, testing could be done in 9211 antenatal mothers. In our 5 years study period, a total of six cases were HIV positive. Out of these HIV positive cases, three were in 2009, no case was detected in 2010, one was in 2011, one in 2012 and one in 2013. Thus, the incidence of HIV (in tested mothers) is 0.13% in 2009, 0 in 2010, 0.06% in 2011, 0.07% in 2012 and 0.05% in 2013. Overall incidence was 0.065%. Conclusion There is a declining trend of HIV prevalence among antenatal mothers reflecting that prevention campaigns are working effectively. How to cite this article Bhadra B , S arkar D , S arkar S ,Chakraborty B. Prevalence of Human Immunodeficiency Virus in Antenatal Mothers in a Rural Tertiary Care Hospital. J South Asian Feder Obst Gynae 2014;6(3):159-162.

Opportunistic infection at the start of antiretroviral therapy and baseline CD4+ count less than 50 cells/mm3 are associated with poor immunological recovery

2019 ◽  
Vol 30 (2) ◽  
pp. 163-171
Author(s):  
Amod Tilak ◽  
Smita Shenoy ◽  
Muralidhar Varma ◽  
Asha Kamath ◽  
Amruta Tripathy ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Opportunistic Infection ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Hiv Positive ◽  
P Value ◽  
Care Hospital ◽  
Long Term Treatment ◽  
Immunological Recovery

AbstractIntroductionThere is a dearth of studies assessing the efficacy and immunological improvement in patients started on antiretroviral therapy (ART) in India. This study was undertaken to assess the 2-year treatment outcomes in HIV-positive patients initiated on ART in a tertiary-care hospital.MethodsAfter approval from the Institutional Ethics Committee, adult HIV-positive patients from a tertiary-care hospital, initiated on ART between January 2013 and February 2015, were included in the study. Data on clinical and immunological parameters were obtained from medical case records over a period of 2 years after initiation of therapy. Intention-to-treat analysis was done using a descriptive approach, using SPSS version 15 (SPSS Inc. Released 2006. SPSS for Windows, Version 15.0. Chicago, SPSS Inc.). A logistic regression analysis was done to assess the predictors for poor outcomes. A p-value <0.05 was considered statistically significant.ResultsART was initiated in 299 adult patients. At 1 and 2 years, the median (interquartile range) change in CD4+cell count was 65 (39, 98) cells/mm3and 160 (95, 245) cells/mm3. The change observed after 2 years of treatment initiation was statistically significant compared with that after 1 year. Three deaths occurred during the study period and 28 were lost to follow-up. Male sex, presence of at least one opportunistic infection at the start of therapy, and baseline CD4+count <50 cells/mm3were associated with poor immunological recovery.ConclusionsWith long-term treatment and regular follow-up, sustained clinical and immunological outcomes can be obtained in resource-limited settings.

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