Non-alcoholic fatty liver disease in pregnancy

2021 ◽  
pp. 1753495X2110347
Author(s):  
Charlotte S Benson ◽  
Jeremy F Cobbold ◽  
Charlotte J Frise

Non-alcoholic fatty liver disease (NAFLD) is now the commonest liver pathology in the UK; however, relatively little is known about its course in pregnancy or the effect it has on maternal or fetal outcomes. Described here is a 24-year-old woman in her first pregnancy who presented with non-specific symptoms and raised alanine aminotransferase with ultrasonography of her liver showing changes of steatosis and suspicious for cirrhosis, leading to a diagnosis of NAFLD. The case illustrates the need for the clinician to have awareness of this increasingly prevalent condition and for multidisciplinary management.

2018 ◽  
Vol 7 (4) ◽  
pp. 664-680 ◽  
Author(s):  
James E. Klaunig ◽  
Xilin Li ◽  
Zemin Wang

Non-alcoholic fatty liver disease is a major cause of chronic liver pathology in humans.


2019 ◽  
Author(s):  
Kushala Abeysekera ◽  
Gwen S. Fernandes ◽  
Gemma Hammerton ◽  
Fiona H. Gordon ◽  
Andrew J. Portal ◽  
...  

2020 ◽  
Vol 73 (3) ◽  
pp. 516-522 ◽  
Author(s):  
Monika Sarkar ◽  
Joshua Grab ◽  
Jennifer L. Dodge ◽  
Erica P. Gunderson ◽  
Jessica Rubin ◽  
...  

2021 ◽  
Vol 27 (3) ◽  
pp. 62-70
Author(s):  
Alexander Boyd ◽  
Ankur Srivastava ◽  
William Rosenberg ◽  
Philip N Newsome ◽  
Matthew J Armstrong

The increasing burden of non-alcoholic fatty liver disease means that robust clinical pathways need to be established in primary care to identify patients with advanced fibrosis who may benefit from specialist management. This article summarises the current landscape of non-invasive liver fibrosis tests and discusses the outcomes and lessons learned from non-alcoholic fatty liver disease pathways that have been instigated around the UK. The inherent challenges of implementing such pathways are explored, along with developing technologies, such as artificial intelligence blood testing, which will likely play an important role in helping to identify and risk-stratify more patients with non-alcoholic fatty liver disease in primary care in the future.


2013 ◽  
Vol 238 (2) ◽  
pp. 151-162 ◽  
Author(s):  
Martin J J Ronis ◽  
January N Baumgardner ◽  
Neha Sharma ◽  
Jamie Vantrease ◽  
Matthew Ferguson ◽  
...  

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