Erectile dysfunction

2018 ◽  
Vol 11 (5) ◽  
pp. 269-276 ◽  
Author(s):  
Patricia Schartau ◽  
Irwin Nazareth ◽  
Asif Muneer ◽  
Mike Kirby

Erectile dysfunction is a common, but treatable, condition. Where appropriate, modification of lifestyle factors, medication optimisation and oral pharmacotherapies can be initiated in primary care. Early recognition and management will improve the quality of life of affected individuals and partners, and may avert relationship problems, negative body image and poor mental health. Erectile dysfunction is also an important early warning sign for conditions such as cardiovascular disease. This article considers the aetiology and risk factors for erectile dysfunction, identifies common clinical features, outlines primary care assessment and treatment, and discusses referral criteria. Treatment options available in secondary care are also reviewed.

2005 ◽  
Vol 288 (1) ◽  
pp. R276-R283 ◽  
Author(s):  
Delphine Behr-Roussel ◽  
Diane Gorny ◽  
Katell Mevel ◽  
Sandrine Compagnie ◽  
Patrick Kern ◽  
...  

Erectile dysfunction (ED) is another manifestation of vascular disease. We evaluated the natural history of ED in the spontaneously hypertensive rat (SHR) and the respective participation of associated pathophysiological modifications, i.e., endothelial dysfunction and tissue remodeling. SHR and their normotensive counterparts [Wistar-Kyoto rats (WKY)] of 6, 12, and 24 wk of age ( n = 12) were used to evaluate erectile function, erectile and aortic tissue reactivity, and remodeling. Erectile responses in SHR are reduced at all ages ( P < 0.001). In both aortic and erectile tissues of SHR and WKY, relaxations to ACh are altered progressively with age, although more markedly in SHR. They are decreased at 12 wk of age in erectile tissue of SHR compared with WKY (maximal relaxation: −19.2 ± 2.8% vs. −28.3 ± 3.9%, P < 0.001) but only at 24 wk of age in aortas (−47.9 ± 6.4% vs. −90.5 ± 2.9%, P < 0.001). Relaxations to sodium nitroprusside are unaltered in aortic rings of both strains but enhanced in erectile tissue of SHR at 12 wk of age. Major modifications in the distribution of collagen I, III, and V in SHR occur in both types of tissue and are detectable sooner in erectile tissue compared with aortic tissue. The onset of ED is detectable before the onset of hypertension in the SHR. Structural and functional alterations, while similar, occur earlier in erectile compared with vascular tissue. If confirmed in humans, ED could be an early warning sign for hypertension, and common therapeutic strategies targeting both ED and hypertension could be investigated.


BJGP Open ◽  
2018 ◽  
Vol 2 (4) ◽  
pp. bjgpopen18X101608
Author(s):  
Rachael C Barlow ◽  
David Sheng Yi Chan ◽  
Sharon Mayor ◽  
Ceri Perkins ◽  
Helen L Lawton ◽  
...  

BackgroundRisk profile assessment and corrective interventions using optimisation of health status and prehabilitation represent an important strategy in the management of patients with a suspected cancer diagnosis.AimTo determine the feasibility of pre-treatment optimisation and prehabilitation commenced at index primary care consultation, to improve patients’ preparation for treatment by maximising the time available.Design & settingBetween January 2015 and May 2016, 195 patients presenting to 12 GP practices were deemed eligible to enter the study, of which 189 (96.9%, median age 60 [21–91] years and 65 months; 124 female) were recruited and consented to the prehabilitation bundle.MethodAll patients were simultaneously referred to secondary care using urgent suspected cancer (USC) pathways. The primary outcome measures were definitive diagnosis and treatment plan.ResultsFifteen patients (7.9%) were diagnosed with cancer (three breast, three colon, two lung, two skin [one melanoma, one sarcoma], one tonsil, one vocal cord, one pancreas, one prostate, one ependymoma) and 62 were diagnosed with other significant medical conditions (47 gastrointestinal, 13 sepsis, two respiratory) requiring secondary care assessment and treatment. Of the 15 patients with cancer, 11 (73.3%) underwent potentially curative treatment, and four (26.7%) palliative treatment. Of the total study cohort, 84 (44%) required a form of optimisation in primary care, and patients with cancer were more likely to require optimisation than others (n = 10 [63%] versus n = 74 [43%], χ2 9.384, P = 0.002).ConclusionOne in 12 primary care USC patients had cancer (5.6% receiving potentially curative treatment), one in three had other systemic health issues, and overall two in five benefited from healthcare intervention. Primary care optimisation was feasible and associated with important allied health benefits.


2005 ◽  
Vol 00 (01) ◽  
pp. 93 ◽  
Author(s):  
Ronald W Lewis ◽  
Mark M Newell

In November 1996, the American Urological Association (AUA) handed down guidelines for treating erectile dysfunction (ED), and urged all physicians to give sound and unbiased explanations of all ED treatments to their patients.1Currently, nearly all urologists and many primary care physicians routinely ask whether their patients are experiencing erectile problems. If the answer is positive, then treatment options are discussed.


2021 ◽  
Vol 3 (3) ◽  
pp. 112-118
Author(s):  
Martin Steggall ◽  
Imran Mohammed ◽  
Keryn Jones ◽  
Anthony Shanahan ◽  
Thomas Ellul ◽  
...  

Erectile dysfunction (ED) is defined as the inability of a man to get and maintain an erection that is sufficient for sexual intercourse, and is a common problem. ED commonly has a profound negative impact on quality of life in the patient and his partner, which can result in changes to sexual self-confidence. This article outlines strategies for identifying and managing ED in primary care, outlining what needs to be assessed and the various treatment options available to manage the condition.


PLoS ONE ◽  
2021 ◽  
Vol 16 (5) ◽  
pp. e0251320
Author(s):  
Magdalena Rzewuska ◽  
Ana Carolina Guidorizzi Zanetti ◽  
Zoë C. Skea ◽  
Leonardo Moscovici ◽  
Camila Almeida de Oliveira ◽  
...  

Improved understanding of multimorbidity (MM) treatment adherence in primary health care (PHC) in Brazil is needed to achieve better healthcare and service outcomes. This study explored experiences of healthcare providers (HCP) and primary care patients (PCP) with mental-physical MM treatment adherence. Adults PCP with mental-physical MM and their primary care and community mental health care providers were recruited through maximum variation sampling from nine cities in São Paulo State, Southeast of Brazil. Experiences across quality domains of the Primary Care Assessment Tool-Brazil were explored through semi-structured in-depth interviews with 19 PCP and 62 HCP, conducted between April 2016 and April 2017. Through thematic conent analysis ten meta-themes concerning treatment adherence were developed: 1) variability and accessibility of treatment options available through PHC; 2) importance of coming to terms with a disease for treatment initation; 3) importance of person-centred communication for treatment initiation and maintenance; 4) information sources about received medication; 5) monitoring medication adherence; 6) taking medication unsafely; 7) perceived reasons for medication non-adherence; 8) most challenging health behavior change goals; 9) main motives for initiation or maintenance of treatment; 10) methods deployed to improve treatment adherence. Our analysis has advanced the understanding of complexity inherent to treatment adherence in mental-physical MM and revealed opportunities for improvement and specific solutions to effect adherence in Brazil. Our findings can inform research efforts to transform MM care through optimization.


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