scholarly journals Early Clinically Relevant Improvement in Quality of Life and Clinical Outcomes 1 Year Postsurgery in Patients with Knee and Hip Joint Arthroplasties

Cartilage ◽  
2017 ◽  
Vol 9 (2) ◽  
pp. 127-139 ◽  
Author(s):  
Audrey Neuprez ◽  
Arnaud H. Neuprez ◽  
Jean-François Kaux ◽  
William Kurth ◽  
Christophe Daniel ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Postoperative Complications ◽  
Hospital Stay ◽  
Minimal Important Difference ◽  
Length Of Hospital Stay ◽  
Good Outcome ◽  
Related Quality ◽  
Health Related ◽  
Joint Arthroplasties

Objective To measure and identify the determinants of the outcomes after hip/knee arthroplasty (HA/KA) in patients with osteoarthritis during the first postsurgical year. Design In this prospective observational study, we evaluated the preoperative and postoperative (3, 6, and 12 months) outcomes of 626 patients who underwent HA (346 with median age 65 years, 59% female) or KA (280 with median age 66.5 years, 54% female) between 2008 and 2013. Generic and specific tools were used to measure health-related quality of life (HRQoL) and utility. Good outcome was defined as an improvement in WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) greater than or equal to the minimal important difference (MID). Regressions were performed to evaluate the relationship between preoperative and postoperative measures and evolution of WOMAC/good outcome. Results We observed an almost systematic improvement of all parameters for up to 12 months, but especially at the 3-month follow-up. The low number of comorbidities and the absence of postoperative complications were the common determinants of improvement of WOMAC total score after 12 months. Other parameters (background of the joint, preoperative function and length of hospital stay in KA group; place of discharge in HA group) affected the evolution of WOMAC scores. 87.09% of HA and 73.06% of KA patients experienced a good outcome. A small number of comorbidities, a worse preoperative function, a shortened hospital stay (KA only), and an absence of early postoperative complications (HA only) significantly predicted a good outcome. Conclusions Intermediate HRQoL following HA or KA improved quickly from preoperative levels for all instruments. More than 70% of patients achieved a good outcome defined as improved pain, stiffness and disability and the predictors are slightly close.

scholarly journals The impact of physical training on length of hospital stay and physical function in patients hospitalized with community-acquired pneumonia: protocol for a randomized controlled trial

Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Camilla Koch Ryrsø ◽  
Daniel Faurholt-Jepsen ◽  
Christian Ritz ◽  
Bente Klarlund Pedersen ◽  
Maria Hein Hegelund ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Hospital Stay ◽  
Usual Care ◽  
Physical Training ◽  
Length Of Hospital Stay ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Abstract Background Community-acquired pneumonia (CAP) is a leading cause of hospitalization worldwide. Bed rest with low levels of physical activity is common during periods of hospitalization and leads to functional decline as well as increased risk of complications. The aim of this study is to assess the effect of supervised physical training during hospitalization with CAP compared with standard usual care for CAP on length of hospital stay, risk of readmission, mortality risk, physical capacity, muscle and fat mass, muscle strength, metabolic function, systemic inflammation, health-related quality of life, and physical activity level. Methods This study is a randomized controlled trial with three parallel experimental arms. Based on a sample size calculation, a total of 210 patients admitted with CAP at Nordsjællands Hospital, Hillerød, Denmark, will be recruited. Patients will be randomly allocated (1:1:1) to either (1) standard usual care, (2) standard usual care combined with in-bed cycling, or (3) standard usual care combined with exercises from a booklet. The primary outcome is differences in length of hospital stay between groups, with secondary outcomes being differences between groups in time to (1) 90-day readmission and (2) 180-day mortality. Further secondary outcomes are differences in changes from baseline between groups in (3) lean mass, (4) fat mass, (5) fat-free mass, (6) physical capacity, (7) health-related quality of life, (8) systemic inflammation, and (9) physical activity level after discharge. Data on length of hospital stay, readmission, and mortality will be collected from patient files, while total lean, fat, and fat-free mass will be quantitated by dual-energy x-ray absorptiometry and bioelectrical impedance analysis. Physical function will be assessed using grip strength, 30-s chair stand tests, and Barthel Index-100. Health-related quality of life will be assessed with the EQ-5D-5L questionnaire. Systemic inflammation will be assessed in blood samples, while accelerometers are used for measuring physical activity. Discussion If a simple physical training program appears to diminish the impact of critical illness and hospitalization on clinical outcome, mobility, and health-related quality of life, it may lead to novel therapeutic approaches in the treatment of patients hospitalized with CAP. Trial registration ClinicalTrials.gov NCT04094636. Registered on 1 April 2019

scholarly journals Long-term health-related quality of life after pancreatic resection for malignancy in patients with and without severe postoperative complications

HPB ◽  
2018 ◽  
Vol 20 (2) ◽  
pp. 188-195 ◽  
Author(s):  
Hanne D. Heerkens ◽  
Lisanne van Berkel ◽  
Dorine S.J. Tseng ◽  
Evelyn M. Monninkhof ◽  
Hjalmar C. van Santvoort ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Postoperative Complications ◽  
Pancreatic Resection ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

The Impact of Critical Illness on Perceived Health-Related Quality of Life During ICU Treatment, Hospital Stay, and After Hospital Discharge

CHEST Journal ◽  
2008 ◽  
Vol 133 (2) ◽  
pp. 377-385 ◽  
Author(s):  
Jose G.M. Hofhuis ◽  
Peter E. Spronk ◽  
Henk F. van Stel ◽  
Guus J.P. Schrijvers ◽  
Johannes H. Rommes ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Critical Illness ◽  
Hospital Stay ◽  
Hospital Discharge ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
The Impact ◽  
Icu Treatment

Preoperative exercise halves the postoperative complication rate in patients with lung cancer: a systematic review of the effect of exercise on complications, length of stay and quality of life in patients with cancer

2018 ◽  
Vol 52 (5) ◽  
pp. 344-344 ◽  
Author(s):  
Daniel Steffens ◽  
Paula R Beckenkamp ◽  
Mark Hancock ◽  
Michael Solomon ◽  
Jane Young
Keyword(s):  
Quality Of Life ◽  
Lung Cancer ◽  
Systematic Review ◽  
Postoperative Complications ◽  
Hospital Stay ◽  
Postoperative Complication ◽  
Length Of Hospital Stay ◽  
Oncological Surgery ◽  
Preoperative Exercise

ObjectiveTo investigate the effectiveness of preoperative exercises interventions in patients undergoing oncological surgery, on postoperative complications, length of hospital stay and quality of life.DesignIntervention systematic review with meta-analysis.Data sourcesMEDLINE, Embase and PEDro.Eligibility criteria for selecting studiesTrials investigating the effectiveness of preoperative exercise for any oncological patient undergoing surgery were included. The outcomes of interest were postoperative complications, length of hospital stay and quality of life. Relative risks (RRs), mean differences (MDs) and 95% CI were calculated using random-effects models.ResultsSeventeen articles (reporting on 13 different trials) involving 806 individual participants and 6 tumour types were included. There was moderate-quality evidence that preoperative exercise significantly reduced postoperative complication rates (RR 0.52, 95% CI 0.36 to 0.74) and length of hospital stay (MD −2.86 days, 95% CI −5.40 to −0.33) in patients undergoing lung resection, compared with control. For patients with oesophageal cancer, preoperative exercise was not effective in reducing length of hospital stay (MD 2.00 days, 95% CI −2.35 to 6.35). Although only assessed in individual studies, preoperative exercise improved postoperative quality of life in patients with oral or prostate cancer. No effect was found in patients with colon and colorectal liver metastases.ConclusionsPreoperative exercise was effective in reducing postoperative complications and length of hospital stay in patients with lung cancer. Whether preoperative exercise reduces complications, length of hospital stay and improves quality of life in other groups of patients undergoing oncological surgery is uncertain as the quality of evidence is low.PROSPEROregistration number

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