scholarly journals Computed tomography angiography lightbulb sign: Characteristic enhancement pattern on neck computed tomography angiography in differentiating paraganglioma from schwannoma of the carotid space

2020 ◽  
Vol 33 (5) ◽  
pp. 437-442
Author(s):  
Suradech Suthiphosuwan ◽  
Helin D Bai ◽  
Eugene Yu ◽  
Aditya Bharatha
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Computed Tomography Angiography ◽  
Preoperative Assessment ◽  
Arterial Phase ◽  
Preoperative Embolization ◽  
Resonance Imaging ◽  
Enhancement Pattern ◽  
Neck Tumors ◽  
Carotid Space

It is important to correctly distinguish paragangliomas from other tumors such as schwannomas in the preoperative assessment of head and neck tumors because paragangliomas have a propensity to bleed profusely during surgery. Therefore, preoperative embolization is often required while with schwannomas preoperative embolization is generally not required. Occasionally, schwannomas can mimic paragangliomas on routine computed tomography and magnetic resonance imaging of the neck. In this study, we retrospectively evaluated the computed tomography angiography of the neck of 10 patients with carotid space tumors. Seven patients had pathologically proven paraganglioma while three patients had schwannomas. We describe the “computed tomography angiography lightbulb sign” as avid homogeneous enhancement in the arterial phase which can accurately distinguish these entities.

Arterial Spin Labeling for the Etiological Workup of Intracerebral Hemorrhage in Children

Stroke ◽  
2021 ◽  
Author(s):  
Jean François Hak ◽  
Grégoire Boulouis ◽  
Basile Kerleroux ◽  
Sandro Benichi ◽  
Sarah Stricker ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Magnetic Resonance ◽  
Intracerebral Hemorrhage ◽  
Computed Tomography Angiography ◽  
Arterial Spin Labeling ◽  
Diagnostic Performance ◽  
Spin Labeling ◽  
Digital Subtraction ◽  
Resonance Imaging

Background and Purpose: Pediatric nontraumatic intracerebral hemorrhage accounts for half of stroke in children. Early diagnostic of the causative underlying lesion is the first step toward prevention of hemorrhagic recurrence. We aimed to investigate the performance of arterial spin labeling sequence (ASL) in the acute phase etiological workup for the detection of an arteriovenous shunt (AVS: including malformation and fistula), the most frequent cause of pediatric nontraumatic intracerebral hemorrhage. Methods: Children with a pediatric nontraumatic intracerebral hemorrhage between 2011 and 2019 enrolled in a prospective registry were retrospectively included if they had undergone ASL-magnetic resonance imaging before any etiological treatment. ASL sequences were reviewed using cerebral blood flow maps by 2 raters for the presence of an AVS. The diagnostic performance of ASL was compared with admission computed tomography angiography, other magnetic resonance imaging sequences including contrast-enhanced sequences and subsequent digital subtraction angiography. Results: A total of 121 patients with pediatric nontraumatic intracerebral hemorrhage were included (median age, 9.9 [interquartile range, 5.8–13]; male sex 48.8%) of whom 76 (63%) had a final diagnosis of AVS. Using digital subtraction angiography as an intermediate reference, visual ASL inspection had a sensitivity and a specificity of, respectively, 95.9% (95% CI, 88.5%–99.1%) and 79.0% (95% CI, 54.4%–94.0%). ASL had a sensitivity, specificity, and accuracy of 90.2%, 97.2%, and 92.5%, respectively for the detection of the presence of an AVS, with near perfect inter-rater agreement (κ=0.963 [95% CI, 0.912–1.0]). The performance of ASL alone was higher than that of other magnetic resonance imaging sequences, individually or combined, and higher than that of computed tomography angiography. Conclusions: ASL has strong diagnostic performance for the detection of AVS in the initial workup of intracerebral hemorrhage in children. If our findings are confirmed in other settings, ASL may be a helpful diagnostic imaging modality for patients with pediatric nontraumatic intracerebral hemorrhage. REGISTRATION: URL: https://www.clinicaltrials.gov ; Unique identifiers: 3618210420, 2217698.

Pitfalls in pancreatic lesion diagnostics: an accessory intrapancreatic spleen

2018 ◽  
pp. 70-80
Author(s):  
A. I. Tyunibabyan ◽  
I. A. Blokhin ◽  
V. Yu. Chernina ◽  
A. R. Kaldarov ◽  
G. G. Karmazanovsky
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Differential Diagnosis ◽  
Magnetic Resonance ◽  
Contrast Enhancement ◽  
Accessory Spleen ◽  
Abdominal Ultrasound ◽  
Resonance Imaging ◽  
Enhancement Pattern ◽  
Intrapancreatic Accessory Spleen

Introduction. Accessory spleen (splenunculus) is one of the most common benign congenital anomalies in humans. The location of splenunculus may vary from perisplenic, greater omental or mesenterial to intraparenchymal (pancreas, stomach, duodenum, etc.). In the latter case, the additional spleen is called ectopic (from the greekektoposdisplaced). Most frequently detection of such splenic lobules occurs accidentally via abdominal ultrasound.Objective: two cases of verified intrapancreatic accessory spleen (IPAS) and main criteria for differential diagnosis with other hypervascular pancreatic lesions.Materials and methods. We present two case reports: a 43-year-old woman with a history of kidney cancer and a healthy 61-year-old man. In both cases, pancreatic neuroendocrine neoplasia (NEN) was initially suspected. Preoperative diagnostics included abdominal ultrasound examination and multiphase dynamic computed tomography (CT) with intravenous bolus nonionic iodine-based contrast agent (native, arterial – 10 sec, venous – 60 sec and delayed – 300 sec after threshold density of 150 HU in the aorta was exceeded). In one case magnetic resonance imaging (MRI) including axial, sagittal and coronal T1and T2-weighted images, diffusion-weighted images and dynamiccontrast-enhanced series with gadolinium chelate was performed. Both patients underwent robotic assisted distal pancreas resection. Morphological examination revealed IPAS.Results. In contrast-enhanced computed tomography IPAS has densitometric parameters similar to the spleen. Generally, magnetic resonance imaging does not differentiate IPAS, NEN and hypervascular metastases, since all three are generally T2-hyperintense and T1-hypointense. Contrast enhancement pattern with gadolinium chelateswas similar to CT-contrast enhancement pattern.Conclusion. Intrapancreatic accessory spleen does not require surgical treatment. Therefore, differential diagnosis between IPAS and neuroendocrine neoplasia, solid pseudopapillary tumor and hypervascular pancreatic metastases is crucial. MRI has an advantage with non-invasive diffusionweighted images (DWI). The apparent diffusion coefficient (ADC) of IPAS will be quantitatively similar to the main spleen while other lesion will demonstrate lower ADC values. Scintigraphy with red blood cells bound with 99mTc utilizes the reticuloendothelial system (RES) in the spleen demonstrating characteristic uptake in the IPASand the main spleen. Ultrasound with color Doppler and contrast enhancement may be a good addition to our armamentarium. One can evaluate the vascular pedicle of the IPAS, as well as contrast agent retention in RES via sonography. We believe the multimodal approach including MRI with DWI/ADC to be the most effective.

Sign in / Sign up

Export Citation Format

Share Document