scholarly journals Prostate adenocarcinoma of secretory type with wide expression of p63 and negativity of the basal marker Ck5/6: Rare subtype of adenocarcinoma of secretory origin and to be differentiated from basal cell carcinoma. Review of literature

Rare Tumors ◽  
2020 ◽  
Vol 12 ◽  
pp. 203636132097194
Author(s):  
Abbas M ◽  
Habibian B ◽  
Bettendorf O

We report a case of prostate carcinoma with wide nuclear expression for p63. These cases are rare and show atypical cytoplasmic/membrane expression of Ck5/6, alpha-methylacyl coenzyme A racemase and high-molecular-weight cytokeratin. It is rare to find this type of carcinoma with negativity for Ck5/6. We would like to present this case to avoid a diagnostic pitfall and with review of literature to understand the origin of this rare subtype.

2018 ◽  
Vol 6 (11) ◽  
pp. 2213-2216
Author(s):  
Lerinza Van der Worm ◽  
Riyaadh Roberts ◽  
Thuraya Isaacs ◽  
Reginald M. Ngwanya

2002 ◽  
Vol 184 (1) ◽  
pp. 313-317 ◽  
Author(s):  
Andrés Yarzábal ◽  
Gaël Brasseur ◽  
Jeanine Ratouchniak ◽  
Karen Lund ◽  
Danielle Lemesle-Meunier ◽  
...  

ABSTRACT A high-molecular-weight c-type cytochrome, Cyc2, and a putative 22-kDa c-type cytochrome were detected in the membrane fraction released during spheroplast formation from Acidithiobacillus ferrooxidans. This fraction was enriched in outer membrane components and devoid of cytoplasmic membrane markers. The genetics, as well as the subcellular localization of Cyc2 at the outer membrane level, therefore make it a prime candidate for the initial electron acceptor in the respiratory pathway between ferrous iron and oxygen.


2015 ◽  
Vol 2015 ◽  
pp. 1-3
Author(s):  
Dhruv Nayyar ◽  
Kavitha Muthiah ◽  
Christopher S. Hayward ◽  
Zerlene Lim ◽  
Emily K. Granger ◽  
...  

Pulmonary tumor thrombotic microangiopathy is a rare but serious malignancy-related respiratory complication. The most common causative neoplasm is gastric adenocarcinoma. We report a case caused by metastatic prostate adenocarcinoma, diagnosed postmortem in a 58-year-old male. To our knowledge, this is the second reported case from metastatic prostate adenocarcinoma.


2013 ◽  
Vol 07 (S 01) ◽  
pp. S126-S134 ◽  
Author(s):  
Bassel Tarakji ◽  
Kusai Baroudi ◽  
Salah Hanouneh ◽  
Saleh Naser Azzeghaiby ◽  
Mohammad Zakaria Nassani

ABSTRACTThis review will highlight some current areas of difficulty or controversy in diagnosis and treatment of nevoid basal cell carcinoma syndrome (NBCCS). The odontogenic keratocyst (OKC) has significant growth capacity and recurrence potential and is occasionally indicative of the NBCCS. The objective of this study is to clarify the causes of the recurrence of OKC in NBCCS. A literature search was conducted using Medline, accessed via the National Library of Medicine PubMed interface, searching for articles relating to the cause of recurrence of keratocyst in NBCCS written in English. This study has described the previous and the current outcomes of the treatment of OKC (recurrent cause). A protocol was then agreed to search for the possible causes of keratocyst recurrence in NBCCS. The general treatment of other manifestation of NBCCS has excluded from this study. Studies describing cohort, case series and miscellaneous clinical reports were retrieved and evaluated from 2010 to 2012.


CytoJournal ◽  
2013 ◽  
Vol 10 ◽  
pp. 16 ◽  
Author(s):  
Maria Luisa C. Policarpio-Nicolas ◽  
Deepika Sirohi

Macrofollicular variant of papillary thyroid carcinoma (MFVPTC) is one of the rarest histologic types of papillary carcinoma. This tumor may mimic an adenomatoid/colloid nodule or follicular neoplasm (macrofollicular type) both on histology and cytology. There are very few articles describing the cytologic features of MFVPTC. We report the cytologic findings of two surgically confirmed MFVPTC. The first case showed abundant thin colloid with moderate amount of follicular cells arranged in a honeycombed and syncytial pattern. Some but not all the follicular cells showed enlarged round to ovoid nuclei, overlapping nuclei, few nuclear grooves and rare intranuclear inclusions. The second case showed abundant thin colloid and predominantly benign appearing follicular cells with few overlapping nuclei, enlarged round to ovoid nuclei and rare nuclear grooves. No intranuclear inclusions were identified. A review of the literature was done and the cytologic findings of MFVPTC including our two cases were tabulated. The cytologic findings showed moderate to abundant thin with focally thick colloid in 75% of cases and sheet like arrangement of follicular cells in 76%. Although nuclear features such as chromatin clearing, overlapping and grooves were present in majority of cases, the quantity varied from rare to focal. Small to prominent nucleoli were present in all of the evaluable cases. Intranuclear inclusions were seen only in 45% of patients. Hence, the cytologic features of macrofollicular variant of papillary carcinoma though present can be subtle and intranuclear inclusions may not be present always.


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