Significant other interactions in people with chronic low back pain: Subgrouping and multidimensional profiles

2021 ◽  
pp. 204946372110620
Author(s):  
Martin Rabey ◽  
Brendan Buldo ◽  
Magnus Duesund Helland ◽  
Courtenay Pang ◽  
Michelle Kendell ◽  
...  
Keyword(s):  
Social Support ◽  
Low Back Pain ◽  
Back Pain ◽  
Chronic Low Back Pain ◽  
Latent Class ◽  
Pressure Pain Threshold ◽  
Significant Other ◽  
Low Back ◽  
One Year ◽  
Cluster 2

Background: Back pain is complex. Social support and significant other interactions influence the pain experience. Purpose: To statistically derive subgroups of people with chronic low back pain based upon their interactions with significant others, and profile subgroups across multidimensional variables. Research Design: Longitudinal cohort study. Study Sample: People with chronic axial low back pain ( n = 262). Data Collection and Analysis: Latent class analysis of significant other interaction data was used to derive subgroups of people with chronic low back pain. Subgroups were profiled across baseline multidimensional variables and one-year follow-up pain intensity, disability and bothersomeness. Results: Three clusters were identified: Cluster 1 (7.6%) characterised by the lowest distracting, punishing and solicitous interactions. Cluster 2 (16.0%) characterised by the highest distracting and solicitous responses and social support. Cluster 3 (76.3%) characterised by the highest punishing and lowest social support. Cluster 1 reported less disability than Clusters 2 and 3. Mindfulness was significantly different across all subgroups with Cluster 1 being most mindful and Cluster 3 least mindful. Depression, anxiety and stress were significantly higher in Cluster 3 than Cluster 1. Pain catastrophising was higher for Cluster 2 than Clusters 1 and 3. Cluster 2 had lower pressure pain threshold than Clusters 1 and 3. Conclusions: These results support the association between significant other interactions and the experience of back pain. Considering significant other interactions in clinical practice may be important for managing some people’s presentation.

Spinal manipulation compared with back school and with individually delivered physiotherapy for the treatment of chronic low back pain: a randomized trial with one-year follow-up

2010 ◽  
Vol 24 (1) ◽  
pp. 26-36 ◽  
Author(s):  
Francesca Cecchi ◽  
Raffaello Molino-Lova ◽  
Massimiliano Chiti ◽  
Guido Pasquini ◽  
Anita Paperini ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Randomized Trial ◽  
Chronic Low Back Pain ◽  
Spinal Manipulation ◽  
Low Back ◽  
Back School ◽  
One Year

One-Year Follow-Up of a Randomized Clinical Trial Comparing Flexion Distraction with an Exercise Program for Chronic Low-Back Pain

2006 ◽  
Vol 12 (7) ◽  
pp. 659-668 ◽  
Author(s):  
Jerrilyn A. Cambron ◽  
M. Ram Gudavalli ◽  
Donald Hedeker ◽  
Marion McGregor ◽  
James Jedlicka ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Low Back Pain ◽  
Back Pain ◽  
Randomized Clinical Trial ◽  
Chronic Low Back Pain ◽  
Exercise Program ◽  
Low Back ◽  
One Year

scholarly journals Emotional and disability status in patients with chronic low back pain

2020 ◽  
Vol 7 (2) ◽  
pp. 57-61
Author(s):  
Mayra Campos Frâncica dos Santos ◽  
João Paulo Manfre dos Santos ◽  
Rubens Alexandre Silva Júnior ◽  
Rosângela Aparecida Pimenta Ferrari ◽  
Ligia Megumi Iida ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Chronic Low Back Pain ◽  
Functional Disability ◽  
Pressure Pain Threshold ◽  
Control Group ◽  
Low Back ◽  
Cross Sectional ◽  
Significance Level ◽  
Control Subjects

Objective: to analyze the prevalence of psychological disorders (anxiety, depression, stress) and the relationship of these factors with functional disability in patients with chronic low back pain. Study design: cross-sectional descriptive and observational study. Setting: the physiotherapy outpatient clinic of the Northen University of Paraná, Londrina, Paraná, Brazil. Methods: 84 individuals were recruited, being 43 elderly (20 with low back pain and 23 control subjects) and 41 adults (21 with low back pain and 20 control subjects). In order to assess the psychological aspects, Beck Inventories of Depression and anxiety as well as Lipp Stress Inventory were used. To evaluate the funcionality, Roland Morris Questionnaire was chosen. The evaluation of the pressure pain threshold was performed using algometer emg systems®. To analyse was considered a significance level of 5% (p<0.05). Results: It was observed that people with low back pain have higher scores of depression, anxiety, stress and functional disability compared to the control group (p<0.05). Among adults, an inverse relationship between anxiety and disability (p<0.05) was observed. In subjects with low back pain positive correlation was observed between anxiety and functional disability and, between the depression and functional disability (p<0.05). In addition, no association was found between stress and functional disability in patients with low back pain (p<0.05). Conclusion: suggest that in patients with low back pain worsening of functionality is anxiety and stress and elderly people with low back pain has higher levels of stress, depression, anxiety and function disability.

Social Support is Inversely Associated with Sleep Disturbance, Inflammation, and Pain Severity in Chronic Low Back Pain

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Anitha Saravanan ◽  
Prempreet Bajaj ◽  
Herbert L. Mathews ◽  
Dina Tell ◽  
Angela Starkweather ◽  
...  
Keyword(s):  
Social Support ◽  
Low Back Pain ◽  
Back Pain ◽  
Sleep Disturbance ◽  
Chronic Low Back Pain ◽  
Pain Severity ◽  
Low Back

The relation of social support and depression in patients with chronic low back pain

2016 ◽  
Vol 39 (15) ◽  
pp. 1482-1488 ◽  
Author(s):  
Ashley B. McKillop ◽  
Linda J. Carroll ◽  
C. Allyson Jones ◽  
Michele C. Battié
Keyword(s):  
Social Support ◽  
Low Back Pain ◽  
Back Pain ◽  
Chronic Low Back Pain ◽  
Low Back

scholarly journals Effectiveness of Parasagittal Interlaminar Epidural Local Anesthetic with or without Steroid in Chronic Lumbosacral Pain: A Randomized, Double-Blind Clinical Trial

2015 ◽  
Vol 3;18 (3;5) ◽  
pp. 237-248 ◽  
Author(s):  
Dr. Babita Ghai
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Pain Relief ◽  
Local Anesthetic ◽  
Chronic Low Back Pain ◽  
Low Back ◽  
Double Blind ◽  
Time Points ◽  
One Year

Background: Epidural injections (EI) are the most commonly performed minimally invasive intervention to manage chronic low back pain (CLBP) with lumbosacral radicular pain (LRP). Local anesthetic (LA) and/ or steroids are frequently used injectates for EI and are reported with variable effectiveness. The majority of earlier studies have used either caudal, transforaminal (TF), or undefined interlaminar approaches for EI. The parasaggital interlaminar (PIL) approach route is reported to have good ventral epidural spread and comparable effectiveness to the TF route. However, there is a lack of head-to-head comparative effectiveness research of LA with or without steroid for managing CLBP with LRP using a PIL approach. Objective: To compare the effectiveness of EI of LA alone and LA with steroid using a PIL approach for managing CLBP with LRP. Study Design: Randomized, double blind, active control one year follow-up study. Setting: Interventional pain management clinic in a tertiary care center in India. Methods: Sixty-nine patients were randomized to receive fluoroscopic guided EI of either 8 mL of 0.5% lidocaine (group L, n = 34) or 6 mL of 0.5% lidocaine mixed with 80 mg (2 mL) of methylprednisolone acetate (group LS, n = 35). Patients were evaluated for pain intensity using 0 – 10 numerical rating scale (NRS) and functional disability using Modified Oswestry Disability Questionnaire (MODQ) at baseline; and 2 weeks, one, 2, 3, 6, 9, and 12 months after injection. Patients with inefficacy with the initial injection or response deterioration received an additional injection of the same injectate and dose. Patients were evaluated for achieving effective pain relief (EPR, i.e., ≥ 50% from baseline), overall NRS and MODQ, number of injections, and presence of ventral and perineural spread over one year follow-up. Primary outcome was proportion of patients achieving EPR at 3 months. Results: A significantly higher proportion of patients achieved EPR at 3 months in group LS [30 (86%, 90% CI 73% – 93%)] as compared to group L [17 (50%, 90% CI 36% – 64%)] (P = 0.02). Similar results were obtained at 6, 9, and 12 months, respectively. The probability of achieving EPR was significantly higher in group LS at various time-points during the one year follow-up as compared to group L (P = 0.01) A significant reduction in NRS and improvement in MODQ were observed at all time-points post-intervention compared to baseline (P < 0.001) in both groups. NRS and MODQ scores were significantly lower in group LS as compared to group L at all time intervals post baseline. On average patients in group L received 2.0 (0.85) and group LS received 1.7 (0.71) injections annually (P = 0.07). Ventral epidural spread was comparable in both groups (97%). No major complications were encountered in either group; however, intravascular spread of contrast was noted during 2 injections (one in each group) requiring relocation. Limitations: A single center study, lack of documentation of adjuvant therapies like individual analgesic medication, and lack of placebo group. Conclusions: Using a PIL approach and the addition of steroid to LA for EI may provide superior effectiveness in terms of extent and duration of pain relief for managing CLBP with unilateral LRP, even though, local anesthetic alone also was effective. Trial registration: CTRI/2014/04/004572 Key words: Epidural injection, epidural steroid, chronic low back pain, chronic lumbosacral pain, parasagittal interlaminar

scholarly journals The Effect of Zoledronic Acid on Serum Biomarkers among Patients with Chronic Low Back Pain and Modic Changes in Lumbar Magnetic Resonance Imaging

Diagnostics ◽  
2019 ◽  
Vol 9 (4) ◽  
pp. 212 ◽  
Author(s):  
Katri Koivisto ◽  
Jaro Karppinen ◽  
Marianne Haapea ◽  
Jyri Järvinen ◽  
Eero Kyllönen ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Zoledronic Acid ◽  
Bone Turnover ◽  
Chronic Low Back Pain ◽  
Placebo Treatment ◽  
Serum Biomarkers ◽  
Modic Changes ◽  
Low Back ◽  
One Year

The aim of the current study was to compare changes in serum biomarkers, including inflammatory mediators, signaling molecules, growth factors and markers of bone turnover after a single intravenous infusion of 5 mg zoledronic acid (ZA, a long-acting bisphosphonate; n = 20) or placebo (n = 20) among patients with Modic changes (MC) and chronic low back pain in a randomized controlled design. The MCs were classified into M1, predominating M1, predominating M2, and M2. We measured the serum concentrations of 39 biomarkers at baseline, and one month and one year after treatment. After Benjamini–Hochberg (B–H) correction, we observed significant differences in three biomarkers over one year: Interferon-γ-inducible protein (IP-10) had risen in the ZA group (p = 0.005), whereas alkaline phosphatase (AFOS) and intact procollagen I N-terminal propeptide (iPINP) had significantly decreased in the ZA group, but had not changed in the placebo group (p < 0.001 for both). Change in iPINP correlated with change in the volume of all MC and M1 lesions. ZA downregulated bone turnover markers as expected and, surprisingly, increased the chemokine IP-10 relative to placebo treatment. This adds to our knowledge of the effects of ZA on MC and the biomarkers that signal this process.

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