scholarly journals The Social Responsiveness Scale (SRS-2) in school-age children with Down syndrome at low risk for autism spectrum disorder

2020 ◽  
Vol 5 ◽  
pp. 239694152096240
Author(s):  
Marie Moore Channell
Keyword(s):  
Autism Spectrum Disorder ◽  
Down Syndrome ◽  
Population Sample ◽  
Autism Spectrum ◽  
Social Responsiveness Scale ◽  
Low Risk ◽  
Spectrum Disorder ◽  
Social Responsiveness ◽  
The Social ◽  
Two Samples

Background and aims Little is known about how autism spectrum disorder (ASD) symptoms present in individuals with Down syndrome (DS). Some behaviors may be symptomatic of comorbid ASD or more broadly representative of the DS phenotype. A prior research study documented elevated ASD-like symptoms in adolescents and young adults with DS without comorbid ASD, using a common ASD risk screening tool—the Social Responsiveness Scale (SRS). The current study applied a similar approach to younger children with DS using the SRS-2. The primary aim was to document patterns of ASD-like symptoms in children with DS at low risk of comorbid ASD to distinguish the symptoms that may be present across DS in general. Methods SRS-2 standard scores were analyzed in a sample of 40 children with DS, 6–11 years old, who were considered to be at low risk for ASD based on the Social Communication Questionnaire (SCQ) screener. Other developmental characteristics (i.e., age, nonverbal IQ, expressive language), social skills, and problem behaviors were also examined across the sample. Results SRS-2 scores were significantly elevated in this sample compared to the normative population sample. A pattern of ASD-like symptomatology was observed across SRS-2 subdomains. These findings were similar to the findings of the prior study. However, nuanced differences were observed across the two samples that may represent developmental differences across different ages in this population. Conclusions Replicating and extending a prior study's findings, certain ASD-like behaviors may occur in individuals with DS who are at low risk for comorbid ASD. Implications: Understanding the pattern of ASD-like behaviors that occur in children with DS who are at low risk for comorbid ASD will help clinicians in screening and identification efforts. In particular, it will lead to better specification of the behaviors or symptoms that are not characteristic of the DS phenotype and thus are red flags for comorbid ASD in this population.

scholarly journals Social Responsiveness Scale (SRS) in Relation to Longitudinal Cortical Thickness Changes in Autism Spectrum Disorder

2018 ◽  
Vol 48 (10) ◽  
pp. 3319-3329 ◽  
Author(s):  
Molly B. D. Prigge ◽  
Erin D. Bigler ◽  
Brittany G. Travers ◽  
Alyson Froehlich ◽  
Tracy Abildskov ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Cortical Thickness ◽  
Autism Spectrum ◽  
Social Responsiveness Scale ◽  
Spectrum Disorder ◽  
Social Responsiveness

Early Screening for Autism Spectrum Disorder

2017 ◽  
Vol 41 (S1) ◽  
pp. s131-s132
Author(s):  
C. Kamuk ◽  
C. Cantio ◽  
N. Bilenberg
Keyword(s):  
Autism Spectrum Disorder ◽  
Population Sample ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Social Responsiveness ◽  
Early Screening ◽  
Developmental Problems ◽  
Children With Asd ◽  
Screening Study ◽  
Competing Interest

IntroductionMost parents to children with Autism Spectrum Disorder (ASD) can report concerns about their child's development within the first year of life. In spite of this, children with ASD are rarely diagnosed before the age of 3–4 years. Early identification allows early intervention, which seems to be substantial for improvement of core behavioural symptoms in children with ASD. The Child Behaviour Checklist for ages 1½ to 5 (CBCL/1½–5) have shown promising utility for early detection of children with ASD.ObjectivesThis study will estimate the positive predictive value of CBCL/1½–5 Pervasive Developmental Problems (PDP) scale in a 2 phase screening study. Furthermore, it will analyse the stability of the CBCL/1½–5 PDP-score in pre-school children from 2½ to 5 years.AimsThe present study aims to validate CBCL/1½–5 for early screening of ASD in a general population sample.MethodsParents, enrolled in the Odense Child Cohort (OCC), answered the CBCL/1½–5 when the child reached 27 months of age. Parents with children above the age of four and a raw score ≥5 (90th percentile) on the PDP scale, received the Social Responsiveness Scale (SRS) questionnaire. Children with a high score on the SRS were invited to a clinical examination consisting of ADOS and ADI-R. Children in OCC were re-assessed with CBCL/1½–5 again at age five years.ResultsResults will be presented at the EPA conference 2017 in Florence.ConclusionsThe results may contribute to enhance the outcome of treatment by detecting children with ASD at an earlier age.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Using the big data approach to clarify the structure of restricted and repetitive behaviors across the most commonly used autism spectrum disorder measures

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Mirko Uljarević ◽  
Booil Jo ◽  
Thomas W. Frazier ◽  
Lawrence Scahill ◽  
Eric A. Youngstrom ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Structural Equation ◽  
Autism Spectrum ◽  
Repetitive Behaviors ◽  
Spectrum Disorder ◽  
Equation Modeling ◽  
Social Responsiveness ◽  
Insistence On Sameness ◽  
Restricted And Repetitive Behaviors ◽  
The Social

Abstract Background Restricted and repetitive behaviors (RRB) in autism spectrum disorder (ASD) encompass several distinct domains. However, commonly used general ASD measures provide broad RRB scores rather than assessing separate RRB domains. The main objective of the current investigation was to conduct a psychometric evaluation of the ability of the Social Responsiveness Scale (SRS-2), the Social Communication Questionnaire (SCQ), the Autism Diagnostic Interview-Revised (ADI-R) and the Autism Diagnostic Observation Schedule (ADOS) to capture different RRB constructs. Methods Exploratory Structural Equation Modeling (ESEM) was conducted using individual item-level data from the SRS-2, SCQ, ADI-R and the ADOS. Data were obtained from five existing publicly available databases. For the SRS-2, the final sample consisted of N = 16,761 individuals (Mage = 9.43, SD = 3.73; 18.5% female); for the SCQ, of N = 15,840 (Mage = 7.99, SD = 4.06; 18.1% female); for the ADI-R, of N = 8985 (Mage = 8.86, SD = 4.68; 19.4% female); and for the ADOS, of N = 6314 (Mage = 12.29, SD = 6.79; 17.7% female). Results The three-factor structure provided the most optimal and interpretable fit to data for all measures (comparative fit index ≥ .983, Tucker Lewis index ≥ .966, root mean square error of approximation ≤ .028). Repetitive-motor behaviors, insistence on sameness and unusual or circumscribed interests factors emerged across all instruments. No acceptable fit was identified for the ADOS. Limitations The five datasets used here afforded a large as well as wide distribution of the RRB item scores. However, measures used for establishing convergent and divergent validity were only available for a portion of the sample. Conclusions Reported findings offer promise for capturing important RRB domains using general ASD measures and highlight the need for measurement development.

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