scholarly journals Multiple Spindle Cell Lipomas of Tongue in 7-Year-Old Child: A Rare Presentation

OTO Open ◽  
2021 ◽  
Vol 5 (4) ◽  
pp. 2473974X2110614
Author(s):  
Sonika Dhari Shrestha ◽  
Uma Bhatta ◽  
Anuj Kayastha ◽  
Tridip Bahadur Pantha
2021 ◽  
Vol 156 (Supplement_1) ◽  
pp. S65-S66
Author(s):  
J Khan ◽  
S Guo

Abstract Introduction/Objective Carcino-sarcoma of the pancreas is a rare tumor and very limited clinical and pathologic data have been reported in the literature. As per World Health Organization (WHO) classification of tumors of the digestive system, the carcinosarcoma of the pancreas is classified together with sarcomatoid carcinoma and anaplastic giant cell carcinomas in undifferentiated carcinoma of pancreas. Carcinosarcoma is a rare entity with very poor prognosis. Methods/Case Report Here we report a rare case of pancreatic carcinosarcoma in a 68 year old male patient who underwent a pancreatoduodenectomy for unilocular cystic mass in the head of the pancreas. The mass grossly replaces the whole head of the pancreas. Histologically, the lesion showed a high-grade spindle cell component and adjacent moderately differentiated adenocarcinoma. On immunohistochemical examination, the carcinomatous component was positive for epithelial markers, and the sarcomatous component was positive for DOG1 and had a focal cytoplasmic staining for S-100. The diagnosis of pancreatic carcinosarcoma was rendered. Treatment options are same as of pancreatic carcinoma. Surgical resection is the best option available for patients. Systemic chemotherapy is indicated for patients with distant metastasis or patients with other contraindications. Despite surgery and adjuvant chemotherapy, recurrence rates are high, and prognosis is poor. However, there are no relevant standard chemotherapies available. Based on the limited number of reported cases, the prognosis of carcinosarcoma of the pancreas appears to be poor. But some cases with long term survival have been reported. There are very few primary pancreatic neoplasms with carcinomatous and sarcomatous components reported in the current literature. Results (if a Case Study enter NA) NA Conclusion This case highlights the importance of familiarity with histopathology of this rare entity, and to order proper immunohistochemical and molecular work-up when there is a suspicious abnormal spindle cell component.


2010 ◽  
Vol 2010 ◽  
pp. 1-4 ◽  
Author(s):  
Oladejo Olaleye ◽  
Bertram Fu ◽  
Ram Moorthy ◽  
Charles Lawson ◽  
Myles Black ◽  
...  

Background. Spindle cell lipoma (SCL) is a benign lipomatous tumour, typically occurring in the posterior neck, shoulder or upper back of elderly males. They compose of fat, CD34 positive spindle cells, and ropey collagen on a myxoid matrix. This case highlights a rare presentation of SCL and the need for pre-operative diagnosis.Case Report. A 63-year-old gentleman presented with a pre-existing left supraclavicular mass that had recently increased in size. FNA and CT Scans were performed and results discussed in the mutidisciplinary team meeting. Excisional biopsy was recommended.Radiology. CT neck showed a left supraclavicular mass of fatty density with fine internal septations. A low-grade liposarcoma could not be excluded.Histopathology. FNA was indeterminate. Histology of specimen showed bland spindle cells with no evidence of malignancy. Immuno-histochemistry showed SCL with CD34 positivity and negative staining on CDK4 and p16.Management. Excision biopsy of the mass was performed which was technically difficult as the mass invaginated around the brachial plexus. The patient recovered well post-operatively with no neurological deficits.Conclusion. Spindle cell lipoma is a rare benign tumour and a pre-operative diagnosis based on the clinical context, imaging and immuno-histochemistry is crucial to management.


2019 ◽  
Vol 2 (2) ◽  
pp. e40-e41
Author(s):  
Muhammad Iqbal ◽  
Sanjay Agarwal ◽  
Iqbal S. Shergill

Spindle cell lipoma (SCL) in the scrotum is a very rare presentation with only a few cases reported in the literature. The most common sites for this benign lesion are the neck, shoulder, and back. We present a 72-year-old male patient with painless swelling on the left half of the scrotum with a histopathological diagnosis of SCL.


2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
S. Patricia ◽  
Das Saikat ◽  
B. Rajesh ◽  
I. Rajesh ◽  
B. Selvamani ◽  
...  

Adenocarcinoma and squamous cell carcinoma account for the vast majority of oesophageal malignancies. Other malignancies known to occur in the oesophagus include melanoma, sarcoma, and lymphoma. Among the sarcomas, carcinosarcoma is the commonest with both carcinomatous and sarcomatous elements followed by leiomyosarcoma of mesenchymal origin. Other sarcomas reported in the literature are liposarcoma, synovial sarcoma, myxofibrosarcoma, Ewing's sarcoma, granulocytic sarcoma, histiocytic sarcoma, schwannoma rhabdomyosarcoma, and epithelioid sarcoma. We report a case of malignant spindle cell tumour of oesophagus. Sarcomas of esophagus present as a polypoid exophytic soft tissue mass. Our patient presented with a stricture which is a rare presentation. Locally aggressive treatment with surgery is beneficial, and local palliative treatment including radiotherapy is worthwhile.


Author(s):  
Tomoaki Imai ◽  
Masahiro Michizawa ◽  
Hidetaka Shimizu ◽  
Takumi Imai ◽  
Naonori Yamamoto ◽  
...  

2017 ◽  
Vol 7 (3) ◽  
pp. 181-184 ◽  
Author(s):  
Niharika Swain ◽  
Shilpa Patel ◽  
Jigna Pathak ◽  
Vishal H Punjabi

ABSTRACT Lipomas are tumors of mature adipose tissue. They are commonly seen in the upper extremities, neck, shoulders, and trunk region. However, oral lipomas are relatively rare. They particularly occur in the areas of fat accumulation, especially the cheek, followed by the tongue, floor of the mouth, buccal sulcus and vestibule, lip, palate, and gingiva. Lipomas can be histopathologically classified into classic lipoma and its variant forms, such as fibrolipomas, spindle cell lipomas, intramuscular lipomas, angiolipomas, salivary gland lipomas, pleomorphic lipomas, myxoid lipomas, and atypical lipomas. There have only been a few cases reported on fibrolipoma involving the lower lip in young individuals. Herein, we present a case report on oral fibrolipoma of the lower lip in a 20-year-old female. How to cite this article Punjabi VH, Patel S, Pathak J, Swain N. Fibrolipoma of Lip in a Young Individual: A Rare Presentation. J Contemp Dent 2017;7(3):181-184.


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