scholarly journals Rare Cause of Stricture Esophagus—Sarcoma: A Case Report and Review of the literature

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
S. Patricia ◽  
Das Saikat ◽  
B. Rajesh ◽  
I. Rajesh ◽  
B. Selvamani ◽  
...  
Keyword(s):  
Palliative Treatment ◽  
Spindle Cell ◽  
Soft Tissue Mass ◽  
Epithelioid Sarcoma ◽  
Granulocytic Sarcoma ◽  
Aggressive Treatment ◽  
Review Of The Literature ◽  
Rare Presentation ◽  
Tissue Mass ◽  
Spindle Cell Tumour

Adenocarcinoma and squamous cell carcinoma account for the vast majority of oesophageal malignancies. Other malignancies known to occur in the oesophagus include melanoma, sarcoma, and lymphoma. Among the sarcomas, carcinosarcoma is the commonest with both carcinomatous and sarcomatous elements followed by leiomyosarcoma of mesenchymal origin. Other sarcomas reported in the literature are liposarcoma, synovial sarcoma, myxofibrosarcoma, Ewing's sarcoma, granulocytic sarcoma, histiocytic sarcoma, schwannoma rhabdomyosarcoma, and epithelioid sarcoma. We report a case of malignant spindle cell tumour of oesophagus. Sarcomas of esophagus present as a polypoid exophytic soft tissue mass. Our patient presented with a stricture which is a rare presentation. Locally aggressive treatment with surgery is beneficial, and local palliative treatment including radiotherapy is worthwhile.

scholarly journals Soft Tissue Tumor Leg - A Rare Presentation of Cutaneous Rhinosporidiosis

2020 ◽  
pp. 1-2
Author(s):  
R. Chithra ◽  
B Sai Dhandapani ◽  
R King Gandhi ◽  
R. Chithra
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Tumor ◽  
Soft Tissue Mass ◽  
Radiological Findings ◽  
Rare Presentation ◽  
Diagnostic Dilemma ◽  
Tissue Mass ◽  
Tissue Tumor ◽  
Typical History ◽  
Polypoidal Growth

Rhinosporidiosis presents commonly as polypoidal growth in nose, but presentation in other sites including skin, genitourinary tract is documented. Cutaneous presentation is rare, which may present as pedunculated swelling or cutaneous ulceration, but presenting as soft tissue tumor is extremely rare. The multifaceted presentation of the disease causes diagnostic dilemma to an unsuspecting physician. Clinical and radiological findings may mislead, but usually typical history helps, and typical histology clinches the diagnosis. We are presenting a case of disseminated cutaneous rhinosporidiosis presented as soft tissue mass lesion in the leg causing diagnostic difficulty due to the rare presentation.

Unusual cause of a painless soft tissue mass of the scalp: a rare presentation of primary intracranial neuroendocrine neoplasm

2021 ◽  
Vol 14 (2) ◽  
pp. e236856
Author(s):  
Susruta Manivannan ◽  
Feras Sharouf ◽  
George Lammie ◽  
Paul Leach
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Mass ◽  
Neuroendocrine Tumour ◽  
Clinical Findings ◽  
Neuroendocrine Neoplasm ◽  
Tumour Resection ◽  
Rare Presentation ◽  
Tissue Mass ◽  
Left Hand ◽  
History Of

Incidental soft tissue lumps in the scalp are a common presenting complaint in clinical practice. However, they may signify more sinister underlying pathologies. Our report examines a 63-year-old man presenting with impaired co-ordination in his left hand following a 3-month history of a painless left retroauricular scalp lump. MRI revealed a large left occipital soft tissue mass eroding through the underlying skull with infiltration into the underlying cerebellum and temporal lobe. Open biopsy confirmed a diagnosis of high-grade intracranial neuroendocrine tumour (NET). At approximately 5 months following successful tumour resection and adjuvant chemotherapy, he developed tumour recurrence and was subsequently palliated, and died at 1 year post diagnosis. Herein, we review other cases of primary intracranial NET, clinical findings, histopathological features and prognosis.

scholarly journals Spindle Cell Hemangioendothelioma

2017 ◽  
Vol 3 ◽  
pp. 2513826X1774068
Author(s):  
Meghan Flood ◽  
Daniel Mckee ◽  
Donald Lalonde
Keyword(s):  
Spindle Cell ◽  
Soft Tissue Mass ◽  
Radical Resection ◽  
Tissue Mass ◽  
Left Posterior ◽  
Local Functional ◽  
Standard Of Practice ◽  
Radical Surgical Resection ◽  
Functional Problems

In this case study, a 33-year-old male presented initially to our clinic in 1989 with a soft tissue mass on his left posterior chest wall that had previously been debulked 3 times beginning in 1973. Pathology from these previous excisions confirmed a spindle cell hemangioendothelioma. Following the previous excisions, the mass recurred and slowly increased in size but did not cause any serious functional effects. At the patient’s first clinical visit with our plastic surgery team in 1989, we offered radical surgical resection of the mass, which was the standard of practice at the time. He declined radical resection. We have followed the patient clinically for over 26 years. Since presentation, the mass has not metastasized or caused any local functional problems.

scholarly journals Acute Promyelocytic Leukemia with FLT3/ITD and RUNX1 Mutation Presenting As Extramedullary Soft Tissue Mass

Blood ◽  
2016 ◽  
Vol 128 (22) ◽  
pp. 5185-5185
Author(s):  
Shahram Mori ◽  
Cai Yuan ◽  
Wesam B. Ahmed ◽  
Rushang D. Patel
Keyword(s):  
Bone Marrow ◽  
Soft Tissue ◽  
Acute Promyelocytic Leukemia ◽  
Soft Tissue Mass ◽  
Promyelocytic Leukemia ◽  
Myeloid Sarcoma ◽  
Rare Presentation ◽  
Tissue Mass ◽  
Significant Information ◽  
Runx1 Mutation

Abstract Background: APL formerly known as AML M3 is a variant of myeloid malignancies characterized by recurrent cytogenetic abnormality of PML/RARA translocation, t(15;17). Myeloid sarcoma, also called granulocytic sarcoma or chloroma, is a very rare presentation of extramedullary APL. In rare cases seen, it presents mainly as CNS disease in relapsed or refractory patients. Extramedullary APL on initial presentation is even rarer. As a result no significant information exists on the prognosis of such patients. Case report: A 50-year-old Caucasian female with no past medical history, presented with 6-month duration of chest pain, which was treated as costochondritis without any improvement. Three months later, a soft tissue mass was identified on her sternum. Complete blood count revealed pancytopenia with white blood cell 3.24 x 103/uL, hemoglobin 10.0 g/dL, platelets 58x 103/uL, absolute neutrophil count 1.13 x103/uL, and monocytes 0.13 x103/uL which indicated "low risk disease". A PET/CT scan revealed a 4.6 cm x 4 cm sternal soft tissue mass. The biopsy of the mass confirmed myeloid sarcoma. Bone marrow biopsy showed acute promyelocytic leukemia, approximately 20% blasts in a hypercellular marrow with 70-80% cellularity. Cytogenesis test was negative. FISH analysis subsequently showed a partial RARA transcript inserted at the PML locus suggestive of a cryptic PML/RARA. This was confirmed by PCR for the fusion transcript PML/RARA from the bone marrow. Next generation genome sequencing identified FLT3/ITD and RUNX1 mutation. The patient was treated as a high risk disease due to the presence of chloroma and immediately started on treatment with Daunorubicin, Arsenic Trioxide (ATO), and All-Trans-Retinoic Acid (ATRA). Conclusion: We present an extremely rare case of APL initially presenting with concomitant extramedullary sternal soft tissue mass with cryptic t(15;17) and somatic mutations in FLT/ITD as well as RUNX1 mutations. To our knowledge this is the first reported case of extramedullary APL with FLT/ITD and RUNX1 mutations. Early recognition of this rare presentation with timely chemotherapy may improve the outcomes of these patients. Disclosures No relevant conflicts of interest to declare.

scholarly journals Giant Cell Tumor of the Pes Anserine Bursa (Extra-Articular Pigmented Villonodular Bursitis): A Case Report and Review of the Literature

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Haitao Zhao ◽  
Aditya V. Maheshwari ◽  
Dhruv Kumar ◽  
Martin M. Malawer
Keyword(s):  
Soft Tissue Mass ◽  
Correct Diagnosis ◽  
Pigmented Villonodular Synovitis ◽  
Incisional Biopsy ◽  
Review Of The Literature ◽  
Resonance Imaging ◽  
Tissue Mass ◽  
Radiographic Findings ◽  
Functional Deficit ◽  
Pigmented Villonodular

Pigmented villonodular synovitis (PVNS) is a rare, benign, proliferating disease affecting the synovium of joints, bursae, and tendon sheaths. Involvement of bursa (PVNB, pigmented villonodular bursitis) is the least common, and only few cases of exclusively extra-articular PVNB of the pes anserinus bursa have been reported so far. We report a case of extra-articular pes anserine PVNB along with a review of the literature. The lesion presented as a painful soft tissue mass in the medial part of the proximal leg. A magnetic resonance imaging showed areas of low to intermediate signals in all sequences and the lesion enhanced heterogeneously with contrast. Diagnosis was confirmed by an incisional biopsy, and an intralesional resection was performed. The postoperative course was uneventful, and the patient is free of disease with no functional deficit at 2 years followup. As with other rare lesions, clinical and radiographic findings in addition to histological examination are essential for correct diagnosis.

scholarly journals Sporadic Retroperitoneal Hemangioblastoma: Report of a Case and Review of the Literature

2017 ◽  
Vol 2017 ◽  
pp. 1-5
Author(s):  
F. G. Jalikis ◽  
B. L. Hoch ◽  
R. Bakthavatsalam ◽  
M. I. Montenovo
Keyword(s):  
Differential Diagnosis ◽  
Soft Tissue ◽  
Soft Tissue Mass ◽  
Final Diagnosis ◽  
Rare Tumor ◽  
Review Of The Literature ◽  
Tissue Mass ◽  
Pathologic Features

We report a case of sporadic isolated hemangioblastoma arising from the retroperitoneum and provide a review of the scarce literature regarding this very rare tumor. Furthermore, we thoroughly describe the pathologic features and the broad differential diagnosis that should always be included in the study of any retroperitoneal soft tissue mass to arrive at the final diagnosis.

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