Sonographic Assessment of Human Lumbar Intervertebral Disks: A Cadaveric Study

2021 ◽  
pp. 875647932110083
Author(s):  
Naomi Winn ◽  
Birender Balain ◽  
Matthew Ockendon ◽  
Victor Cassar-Pullicino ◽  
Radhesh Lalam

Objectives: The intervertebral disk has traditionally been imaged by magnetic resonance imaging (MRI); however, advances in sonography mean it can now be visualized with this modality. The objectives of this human cadaveric study were to visualize the internal structure of the lumbar intervertebral disks and map any defects. Shear wave sonography was explored as a method for assessing the disks. Materials and Methods: In a human cadaver, L4-L5 and L5-S1 disks were imaged with sonography through the anterior abdominal wall and directly through the anterior longitudinal ligament. Gray-scale images and shear wave elastography velocities were obtained. An MRI was performed for image comparison. Results: Defects in the disks were clearly seen with sonography, imaging through the anterior abdominal wall and also directly through the anterior longitudinal ligament. The defects identified on sonography were less well visualized on MRI. Shear wave velocities could only be obtained from the anterior aspect of the disk and were unreliable, primarily owing to the stiffness of the tissues. Conclusion: Sonography can provide an accurate map of defects within the disk, corresponding with MRI. Shear wave elastography should be used with caution in the human cadaveric intervertebral disk, acknowledging the many confounding factors influencing the measurements.

2020 ◽  
Vol 46 (7) ◽  
pp. 1651-1657
Author(s):  
Xiaohong Wang ◽  
Kai He ◽  
Yulan Zhu ◽  
Xiaojian Fu ◽  
Zhifang Huang ◽  
...  

2020 ◽  
Vol 99 ◽  
pp. 109498 ◽  
Author(s):  
Naoya Iida ◽  
Keigo Taniguchi ◽  
Kota Watanabe ◽  
Hiroki Miyamoto ◽  
Tatsuya Taniguchi ◽  
...  

2017 ◽  
Vol 61 ◽  
pp. 131-136 ◽  
Author(s):  
Taku Hatta ◽  
Hugo Giambini ◽  
Yoshiaki Itoigawa ◽  
Alexander W. Hooke ◽  
John W. Sperling ◽  
...  

2016 ◽  
Vol 37 (01) ◽  
pp. 1-5 ◽  
Author(s):  
F. Piscaglia ◽  
V. Salvatore ◽  
L. Mulazzani ◽  
V. Cantisani ◽  
C. Schiavone

2019 ◽  
Vol 21 (1) ◽  
pp. 22
Author(s):  
San Min Lee ◽  
Won Chang ◽  
Hyo-Jin Kang ◽  
Su Joa Ahn ◽  
Jeong-Hoon Lee ◽  
...  

Aims: To compare the applicability, reliability and stiffness values of four different shear wave elastography (SWE) platforms and to determine the influence of abdominal wall thickness on those of four SWE platforms evaluating liver fibrosis. Material and methods: We used four different SWE platforms: transient elastography (TE), pSWE (S-shear wave), 2D SWE/ SSI (SuperSonic Imagine) and 2D SWE/GE (GE Health care). To identify the effect of abdominal wall thickness, five commercially available liver fibrosis phantoms were covered in 1.3 cm and 2.3 cm thick porcine abdominal walls, respectively. All measurements were performed by three observers. Absolute repeatability of each measurement was evaluated using coefficients of variation (CVs). Applicability rate, CVs and mean stiffness values were compared according to platforms and abdominal wall thickness.Results: Applicability rates were significantly different among the four SWE platforms (p<0.001): 2DSWE/SSI showed the lowest applicability rate (68.9%) compared with the other three platforms (TE, 95.6%, pSWE, 93.3%, 2D SWE/GE, 97.8%) due to higher technical failure rates in phantoms with thick wall. Repeatability was significantly different according to the platform and abdominal wall thickness. Stiffness values did not significantly differ according to abdominal wall thickness, even though the values were significantly different among four platforms in all phantoms.Conclusions: The applicability, repeatability, and stiffness value were different depending on SWE platforms. Further, the applicability and repeatability would be more affected by abdominal wall thickness. Thus, careful consideration should be given to an appropriate SWE platform, when evaluating liver fibrosis in patients with thick abdominal wall.


2018 ◽  
Vol 60 (4) ◽  
pp. 535-541 ◽  
Author(s):  
Malene Roland Pedersen ◽  
Palle Jørn Sloth Osther ◽  
Henrik Dahl Nissen ◽  
Peter Vedsted ◽  
Henrik Møller ◽  
...  

Background Ultrasound elastography is increasingly available in clinical practice. Recent studies showed higher velocity stiffness in testicular tumors compared to normal testicles. Purpose To evaluate ultrasound elastography in combination with the apparent diffusion coefficient measurements in diffusion weighted (DW) magnetic resonance imaging (MRI) in testicles. DW can be a useful tool in evaluating testicular malignancies. However, the relationship between velocity stiffness and MRI diffusion is not well established. Material and Methods We prospectively included 132 patients with testicular microlithiasis (n = 53), or normal testicular tissue (n = 53), or suspected for testicular cancer (n = 26). All 132 patients underwent ultrasonography including shear wave elastography and MRI diffusion coefficient examination of the scrotum. Results No clinically relevant difference in velocity stiffness was found between normal and testicles with microlithiasis. There was a significant difference in stiffness between patients with testicular microlithiasis (0.78 m/s), normal testicular tissue (0.77 m/s), and patients with testicular cancer (1.95 m/s) ( P ≤ 0.001). Similarly, there was a statistically significant difference in MRI diffusion values between patients with testicular microlithiasis (0.978 × 10−3 mm2 s−1), normal testicular tissue (0.929 × 10−3 mm2 s−1), and testicular cancers (0.743 × 10−3 mm2 s−1) ( P < 0.01). Conclusion Patients with testicular microlithiasis had no malignant characteristics measured with shear wave elastography or MRI diffusion. MRI diffusion and elastography may be useful to preoperatively differentiate benign from malignant testicular lesions.


2019 ◽  
Vol 45 (10) ◽  
pp. 2697-2703 ◽  
Author(s):  
Young Seo Cho ◽  
Sanghyeok Lim ◽  
Yongsoo Kim ◽  
Tae Yeob Kim ◽  
Woo Kyoung Jeong ◽  
...  

Author(s):  
Anders Batman Mjelle ◽  
Anesa Mulabecirovic ◽  
Roald Flesland Havre ◽  
Edda Jonina Olafsdottir ◽  
Odd Helge Gilja ◽  
...  

Abstract Purpose Liver elastography is increasingly being applied in screening for and follow-up of pediatric liver disease, and has been shown to correlate well with fibrosis staging through liver biopsy. Because time is of the essence when examining children, we wanted to evaluate if a reliable result can be achieved with fewer acquisitions. Materials and Methods 243 healthy children aged 4–17 years were examined after three hours of fasting. Participants were divided into four age groups: 4–7 years; 8–11 years; 12–14 years and 15–17 years. Both two-dimensional shear wave elastography (2D-SWE; GE Logiq E9) and point shear wave elastography (pSWE; Samsung RS80A with Prestige) were performed in all participants, while transient elastography (TE, Fibroscan) was performed in a subset of 87 children aged 8–17 years. Median liver stiffness measurement (LSM) values of 3, 4, 5, 6, 7, and 8 acquisitions were compared with the median value of 10 acquisitions (reference standard). Comparison was performed for all participants together as well as within every specific age group. We investigated both the intraclass correlation coefficient (ICC) with absolute agreement and all outliers more than 10 %, 20 % or ≥ 0.5 or 1.0 kPa from the median of 10 acquisitions. Results For all three systems there was no significant difference between three and ten acquisitions, with ICCs ≥ 0.97. All systems needed 4 acquisitions to achieve no LSM deviating ≥ 1.0 kPa of a median of ten. To achieve no LSM deviating ≥ 20 % of a median of ten acquisitions, pSWE and TE needed 4 acquisitions, while 2D-SWE required 6 acquisitions. Conclusion Our results contradict recommendations of 10 acquisitions for pSWE and TE and only 3 for 2D-SWE.


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