scholarly journals Automated volumetric quantification of lung emphysema: the effect of bronchiectasis and infectious lung destruction

Author(s):  
Nadezda Griva ◽  
Pavel Gavrilov
2021 ◽  
Vol 11 (4) ◽  
pp. 37-43
Author(s):  
P. V. Gavrilov ◽  
N. A. Griva ◽  
E. A. Torkatyuk

The aim of this study: to assess the ability of different software products to automated volumetric quantification of lung emphysema and see whether the results can be interconvertible.Materials and methods. This study is based on the results of recognition and analysis of computer tomograms using three different software products.Results: all the programs we used have high sensitivity and specificity in recognition of lung emphysema. However, there are a number of errors that prevent accurate image analysis.Conclusions. The interconvertibility of the results of the automated volumetric quantification of lung emphysema at this stage is not reliably determined and depends on the choice of software products used for analysis.


Minerals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 212
Author(s):  
Noemí Barral ◽  
Raúl Husillos ◽  
Elena Castillo ◽  
Manuel Cánovas ◽  
Elizabeth J. Lam ◽  
...  

This study deals with the potential use of water stored in a lake formed by Reocín’s old zinc mine, which has become the second most important reservoir in Cantabria, with a flow of 1300 L s−1. The methodology used is based on the hydrogeological and hydrochemical characterization of the area studied. A total of 16 piezometers were installed to monitor the amount and quality of water. Results obtained show a pH close to 8 and iron, manganese, zinc, and sulphate concentrations lower than 0.05 mg L−1, 0.05 mg L−1, 1.063 mg L−1, and 1305.5 mg L−1, respectively. The volume of the water stored in the lake amounts to 34 hm3. Measurements show that Fe, Mn, and Zn concentrations are below the limits acceptable for human consumption, according to the Spanish 0.2, 0.05, and 5.0 mg L−1 standards, respectively, while sulphate greatly exceeds the 250 mg L−1 limit accepted by the norm. Therefore, the water could be apt for human consumption after a treatment appropriate for decreasing the sulphate level by, for example, reverse osmosis, distillation, or ion exchange. Although industrial and energy uses are possible, the lake water could be utilized as a geothermal energy source. The management of the hydric resources generated when a mine is closed could improve the economic and environmental conditions of the zone, with all the benefits it brings about, thus allowing for compensating of the pumping cost that environmental protection entails, creating, at the same time, a new business opportunity for the company that owns the mine.


2013 ◽  
pp. 54 ◽  
Author(s):  
Stylianos Mavridis ◽  
Hans-Georg Gnauk ◽  
Martina Schumacher ◽  
Roland H. Wagner

2018 ◽  
Vol Volume 13 ◽  
pp. 3321-3330
Author(s):  
Andreas Ronit ◽  
Thomas Kristensen ◽  
Yunus Çolak ◽  
Jørgen Tobias Kühl ◽  
Anna Kalhauge ◽  
...  

2021 ◽  
Vol 12 ◽  
Author(s):  
Sun-Young Oh ◽  
Marianne Dieterich ◽  
Bit Na Lee ◽  
Rainer Boegle ◽  
Jin-Ju Kang ◽  
...  

Objective: Intravenous contrast agent enhanced, high-resolution magnetic resonance imaging of the inner ear (iMRI) confirmed that patients with Menière's disease (MD) and vestibular migraine (VM) could present with endolymphatic hydrops (EH). The present study aimed to investigate EH characteristics and their interrelation to neurotologic testing in patients with VM, MD, or VM with concurrent MD (VM-MD).Methods: Sixty–two patients (45 females, aged 23–81 years) with definite or probable VM (n = 25, 19 definite), MD (n = 29, 17 definite), or showing characteristics of both diseases (n = 8) were included in this study. Diagnostic workup included neurotologic assessments including video-oculography (VOG) during caloric stimulation and head-impulse test (HIT), ocular and cervical vestibular evoked myogenic potentials (o/cVEMP), pure tone audiometry (PTA), as well as iMRI. EH's degree was assessed visually and via volumetric quantification using a probabilistic atlas-based segmentation of the bony labyrinth and volumetric local thresholding (VOLT).Results: Although a relevant number of VM patients reported varying auditory symptoms (13 of 25, 52.0%), EH in VM was only observed twice. In contrast, EH in VM-MD was prevalent (2/8, 25%) and in MD frequent [23/29, 79.3%; χ2(2) = 29.1, p < 0.001, φ = 0.7]. Location and laterality of EH and neurophysiological testing classifications were highly associated (Fisher exact test, p < 0.005). In MD, visual semi-quantitative grading and volumetric quantification correlated highly to each other (rS = 0.8, p < 0.005, two-sided) and to side differences in VOG during caloric irrigation (vestibular EH ipsilateral: rS = 0.6, p < 0.05, two-sided). In VM, correlations were less pronounced. VM-MD assumed an intermediate position between VM and MD.Conclusion: Cochlear and vestibular hydrops can occur in MD and VM patients with auditory symptoms; this suggests inner ear damage irrespective of the diagnosis of MD or VM. The EH grades often correlated with auditory symptoms such as hearing impairment and tinnitus. Further research is required to uncover whether migraine is one causative factor of EH or whether EH in VM patients with auditory symptoms suggests an additional pathology due to MD.


2005 ◽  
pp. 84-86
Author(s):  
P. Wex ◽  
V. Haas ◽  
E. Utta

The aim of the study was to search delayed results and to characterize patients with heterogeneous emphysema which do not improve their quality of life after lung volume reduction surgery. Retrospective analysis was done based on medical history reports from July, 1994, to January, 1998. The surgical lung volume reduction was performed in 81 patients (45 males and 13 females, the average age was 61.9 yrs). Postoperative mortality was 6.9 % (4 patients). Twenty-three patients died within 5 yrs after the intervention; their mean follow-up period was 33.3 months. The average follow-up period was 54.3 months. Functional parameters for patients survived 3 to 5 yrs were: FEV1 50 ± 23.8 %, RV 35.6 ± 29.1 %, RV / TLC 12.3 ± 12 %, the 6-min walk distance was 96.7 ± 62 m. The total 5-year survival was 63.8 %, the survival for the patients having FEV1> 30 % was 83.8 % and that for the patients with FEV1 < 30 % was 50 %. Age and lung function parameters did not differ in survivors and died patients. On the contrary, differences in the blood gas parameters, oxygen therapy time and 6-min walk distance were significant between these groups. Some negative factors were revealed: predominant injury of the lower lung fields, FEV1 < 30 % pred., respiratory failure (PaCO2 ≥ 48 mm Hg), oxygen therapy longer than 6 months, the 6-min walk distance shorter than 80 m.


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