Association of combined anxiety and depression with quality of life, dyspnea, exercise tolerance in COPD patients

Author(s):  
Abebaw Mengistu Yohannes ◽  
Richard Casaburi ◽  
Sheila Dryden ◽  
Nicola Alexander Hanania
2007 ◽  
Vol 135 (7-8) ◽  
pp. 419-424 ◽  
Author(s):  
Branislava Milenkovic ◽  
Slavica Zizic-Borjanovic ◽  
Srdjan Borjanovic ◽  
Predrag Rebic

Introduction The role of rehabilitation programmes in chronic obstructive pulmonary disease (COPD) patients is to lower dyspnoea, improve exercise tolerance and quality of life. Objective We have developed a short-course, home-based, rehabilitation programme of physical exercise for lower limb muscles, based on walking at patients? fastest pace. The aim of the study was to investigate the effectiveness of such a programme regarding the exercise tolerance, pulmonary functions and quality of life. Method Twenty-nine individuals with stable COPD (22 males, 7 females), with a mean age of 59.6?8.9 years participated in the study. Subjects were assessed before and after the 8-week rehabilitation programme using the six-minute walking test (6MWT), Borg breathlessness score, oxygen saturation, St. George?s Hospital Respiratory Questionnaire (SGRQ), the Hospital Anxiety and Depression Scale (HADS) and spirometry. Results The 6MWT distance improved significantly from 337 to 362 m, representing 8.3% (25 m) improvement over baseline. SGRQ activity, impact and total scores improved significantly after the rehabilitation programme (p<0.01) and quality of life, too. Anxiety and depression scores were significantly lower than the baseline (p<0.01), as well as dyspnoea sensation (p<0.01). Pulmonary function improved after an eight-week exercise programme, too (p<0.01). Conclusion This short-term and simple home-based exercise programme improved health status in COPD. It also improved exercise tolerance, breathlessness sensation and quality of life in COPD patients.


2021 ◽  
pp. 1-8
Author(s):  
Yating Zhang ◽  
Xiangfang Zhao

<b><i>Background:</i></b> Chronic obstructive pulmonary disease (COPD) is a chronic respiratory condition. COPD causes a heavy burden on the patients through negative impacts on the quality of life and psychological health. The health belief model (HBM) is proposed and modified by several social psychologists and is confirmed to have benefits in the recovery of various diseases. This research aimed to explore the effects of the HBM-based intervention on anxiety, depression, and quality of life in COPD patients entering pulmonary rehabilitation (PR). <b><i>Methods:</i></b> This research was conducted at the Tianjin Rehabilitation Recuperate Center of Chinese PLA in 2019. A total of 136 COPD patients were randomized into the intervention group and the control group. In the control group, patients received the PR program. In the intervention group, patients received both PR program and the HBM-based intervention. Quality of life was measured by the COPD assessment test. The outcomes of anxiety and depression were measured by the Hospital Anxiety and Depression Scale. <b><i>Results:</i></b> The HBM-based intervention decreased both anxiety and depression scores among COPD patients. The COPD assessment test score was declined by the HBM-based intervention, which also decreased the serum levels of interleukin-6 and C-reactive protein in COPD patients entering PR. <b><i>Conclusion:</i></b> The HBM-based intervention alleviates anxiety and depression, enhances quality of life, and inhibits inflammation in COPD patients entering PR.


2002 ◽  
Vol 7 (2) ◽  
pp. 125-133 ◽  
Author(s):  
Antonio Galán Rodríguez ◽  
Alfonso Blanco Picabia ◽  
Angeles Pérez San Gregorio

The concepts of illness behavior (IB), coping (C), and health-related quality of life (HQL) are commonly used in the health field. Nevertheless, there are doubts about their ability to discriminate among groups of patients and to predict anxiety and depression levels in some medical settings. Three groups of patients (ambulatory chronic obstructive pulmonary disease ‘COPD’ patients, hospitalized COPD patients, and surgical lung cancer patients) were evaluated on the basis of these concepts using three standard questionnaires. Discriminant analysis was performed to study the discriminative properties of concepts; the eigenvalues were 3.470 (IB), 0.989 (C) and 5.591 (HQL). Stepwise multiple regression analyses were performed to identify the concepts and the scales that could best predict anxiety and depression. For anxiety, adjusted R2 were 0.408 (IB), 0.140 (C) and 0.633 (HQL); for depression, adjusted R2 were 0.264 (IB), 0.079 (C) and 0.635 (HQL). Coping had the greatest difficulty differentiating among persons suffering from different diseases; the efficiency to predict an affective state was poor in IB, C, and HQL. Some implications of the results are discussed.


2013 ◽  
Vol 12 (4) ◽  
pp. 398-404
Author(s):  
H Ahmad ◽  
M Justine ◽  
Z Othman ◽  
V Mohan ◽  
FT Mirza

Objective: The objective of this study was to identify the outcomes of short term inspiratory muscle training (IMT) combined with chest physiotherapy (CP) on lung function, inspiratory muscle strength, exercise tolerance and quality of life of COPD patients. Materials and Methods: This randomized-controlled trial was conducted at the Terendak Armed Forces Hospital, Melaka. Eighteen hospitalized COPD patients (FEV1 50% to = 80% predicted) were randomized into intervention (IG) and control group (CG). The IG received IMT and CP treatments whilst the CG received only CP for a period of 4 weeks. Assessments of lung function (FEV1/FVC), inspiratory muscle strength (PImax), exercise tolerance (6MWT) and quality of life (SGRQ score) were taken at baseline and after 4 weeks. Results: Analysis showed IG group increased in FEV1/FVC by 19.4%, PImax by 54.7%, 6MWT by 33.2% and quality of life by 52.6% (All, p<0.05). The control group increased in FEV1/FVC by 8.7% (p>0.05), PImax by 15% (p<0.05), 6MWT by 18.9% (p<0.05) and quality of life by 15.6% (p<0.05). Conclusion: The present study has established that by combining inspiratory muscle training (IMT) and chest physiotherapy, provides superior effects on lung function, inspiratory muscle strength, exercise tolerance and quality of life among COPD patients. DOI: http://dx.doi.org/10.3329/bjms.v12i4.13302 Bangladesh Journal of Medical Science Vol. 12 No. 04 October ’13 Page 398-404


1999 ◽  
Vol 19 (5) ◽  
pp. 317
Author(s):  
M. E. Dominguez ◽  
P. Fernandez de la Vega ◽  
O. Herrera ◽  
O. Borrego ◽  
E. Romero ◽  
...  

2019 ◽  
Vol 39 (2) ◽  
pp. 121-129
Author(s):  
Dessy Mizarti ◽  
Deddy Herman ◽  
Yessy S Sabri ◽  
Amel Yanis

Background: Anxiety and depression among COPD patients can lead to physical limitation, lung function deterioration, risk of exacerbation and poor quality of life. This study aims to investigate correlation between anxiety and depression with quality of life among COPD patients Method: This was cross sectional analytic study recruiting COPD patients in Pulmonary outpatient setting in Dr. M. Djamil Central Hospital Padang and Achmad Mochtar Hospital Bukittinggi from January to March 2017. Samples were recruited through consecutive technique (accidental sampling). Result: Results showed from 101 COPD patients, average age was 65,54 + 9,99 years old. Mostly were male 83,17%, basic education 71,29%, low economical status 58,42%, married 81,19%, ex smoker 71,29%, severe Brinkman index 60,40%. There was correlation between gender (p value =0,002) and marital status (p value =0,010) with anxiety and or depression. Severe COPD patients tend to suffer from anxiety, depression, anxiety and depression, as many as 34,78%, 100% and 54,55%, respectively. Most COPD patients who suffered from anxiety and depression had poor quality of life 28,57%. There was correlation between anxiety and or depression with quality of life among COPD patients p-value= 0,005. COPD patients in D group often had poor quality of life 82,14%. There was correlation between COPD population group and quality of life (p-value=0,001). Conclusion: Anxiety and depression could occur in every stage of COPD, especially severe COPD. There was correlation between anxiety and or depression with quality of life so thus COPD treatment should embrace the comorbid factors. (J Respir Indo 2019; 39(2): 121-9)


2013 ◽  
Vol 8 ◽  
Author(s):  
Stefano Marinari ◽  
Maria Rosaria Manigrasso ◽  
Fernando De Benedetto

Background: The protein-calorie malnutrition, resulting in muscle mass loss, frequently occurs in severe COPD patients with chronic respiratory failure (CRF), causing dyspnea, reduced exercise tolerance and impaired quality of life. The cause of this occurrence is an intake-output energy imbalance. A documented deficit of phosphocreatine and reduced mithocondrial energy production can contribute to this imbalance. Aim of this study is to verify whether a dietary supplementation with creatine and coenzyme Q10, important mitochondrial function factors, is able to influence this mechanism leading to a dyspnea reduction and improving exercise tolerance and quality of life. Methods: 55 COPD patients with chronic respiratory failure (in long term O2 therapy), in stable phase of the disease and without severe comorbidities were assigned (double-blind, randomized) to: group A (30 patients) with daily dietary supplementation with Creatine 340 mg + 320 mg Coenzyme Q-Ter (Eufortyn®, Scharper Therapeutics Srl) for 2 months whereas Group B (25 patients) received placebo. All patients continued the same diet, rehabilitation and therapy during the study. At recruitment (T0) and after 2 months (T1), patients were submitted to medical history, anthropometry (BMI), bioelectrical impedance, arterial blood gas analysis, evaluation of dyspnea (VAS, Borg, BDI, MRC) and functional independence (ADL), 6-minute walk test (6MWT) and quality of life questionnaire (SGRQ). At 6 months and 1 year, a telephone follow up was conducted on exacerbations number. Results: No significant difference was detected at baseline (T0) in the 2 groups. After 2 months of therapy (T1) the FFMI increased in the daily dietary supplementation group (+ 3.7 %) and decreased in the placebo group (− 0.6 %), resulting in a statistically significant (p < 0.001) treatment difference. Statistically significant treatment differences, favouring daily dietary supplementation group, were also seen for the 6MWT comparison. Group A patients also showed significant: 1) improvement in the degree of dyspnea (VAS: p < 0.05; Borg: p < 0.05; MRC: p < 0.001; BDI1: p < 0.05; BDI3: p < 0.03), and independence level in activities of daily living (p < 0.03); 2) improvement in quality of life in activity section (− 6.63 pt) and in total score (− 5.43 pt); 3) exacerbation number decrease (p < 0.02). No significant differences were found (end of study vs baseline) in group B. Conclusions: The nutraceutical diet integration with Q-Ter and creatine, in COPD patients with CRF in O2TLT induced an increasing lean body mass and exercise tolerance, reducing dyspnea, quality of life and exacerbations. These results provide a first demonstration that acting on protein synthesis and muscular efficiency can significantly modify the systemic consequences of the disease.


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