scholarly journals Lung cancer mortality in Europe and the United States between 2000 and 2017: an observational analysis

2021 ◽  
pp. 00311-2021
Author(s):  
Chinmay Jani ◽  
Dominic C Marshall ◽  
Harpreet Singh ◽  
Richard Goodall ◽  
Joseph Shalhoub ◽  
...  
Keyword(s):  
United States ◽  
Lung Cancer ◽  
Cancer Mortality ◽  
Lung Cancer Mortality ◽  
The United States ◽  
Mortality Rates ◽  
World Health ◽  
Female Mortality ◽  
The Us ◽  
Male To Female

BackgroundThe lung is the most common site for cancer and has the highest worldwide cancer-related mortality. Our study reports and compares trends in lung cancer mortality in the United States (US) and 26 European countries.Study design and methodsLung cancer mortality data were extracted for males and females for each of the years 2000–2017 from the World Health Organization (WHO) Mortality and the Centers for Disease Control and Prevention (CDC) WONDER databases. Lung cancer mortality trends were compared using Joinpoint regression analysis, and male-to-female mortality ratios were calculated.ResultsDown-trending lung cancer mortality rates were observed in males in all countries except Cyprus and Portugal between 2000 and 2017. In females, increasing mortality rates were observed in 22 of the 27 countries analyzed. Latvia had the highest estimated annual percentage change (EAPC) in male mortality (−9.6%) between 2013–2015. In the US, EAPCs were −5.1% for males and −4.2% for females between 2014–2017. All countries had an overall decrease in the ratio of male-to-female lung cancer mortality. The most recent observation of median male-to-female mortality was 2.26 (IQR 1.92–4.05). The countries with the greatest current sex disparity in lung cancer mortality were Lithuania (5.51) and Latvia (5.00).ConclusionBetween 2000 and 2017, lung cancer mortality rates were decreasing for males in Europe and the US, whereas increasing lung cancer mortality rates were generally observed in females. There is a persistent but decreasing sex-mortality gap, with men having persistently greater lung cancer mortality but with rates decreasing faster than women.

Lung cancer mortality rates in birth cohorts in the United States from 1960 to 1994

Lung Cancer ◽  
2001 ◽  
Vol 31 (2-3) ◽  
pp. 91-99 ◽  
Author(s):  
David M. Mannino ◽  
Earl Ford ◽  
Gary A. Giovino ◽  
Michael Thun
Keyword(s):  
United States ◽  
Lung Cancer ◽  
Cancer Mortality ◽  
Lung Cancer Mortality ◽  
The United States ◽  
Mortality Rates ◽  
Birth Cohorts

scholarly journals Reduced Lung Cancer Mortality With Lower Atmospheric Pressure

Dose-Response ◽  
2018 ◽  
Vol 16 (2) ◽  
pp. 155932581876948 ◽  
Author(s):  
Ray M. Merrill ◽  
Aaron Frutos
Keyword(s):  
United States ◽  
Lung Cancer ◽  
Cancer Mortality ◽  
Atmospheric Pressure ◽  
Regression Models ◽  
Spatial Regression ◽  
Lung Cancer Mortality ◽  
The United States ◽  
Mortality Rates ◽  
County Level

Background: Research has shown that higher altitude is associated with lower risk of lung cancer and improved survival among patients. The current study assessed the influence of county-level atmospheric pressure (a measure reflecting both altitude and temperature) on age-adjusted lung cancer mortality rates in the contiguous United States, with 2 forms of spatial regression. Methods: Ordinary least squares regression and geographically weighted regression models were used to evaluate the impact of climate and other selected variables on lung cancer mortality, based on 2974 counties. Results: Atmospheric pressure was significantly positively associated with lung cancer mortality, after controlling for sunlight, precipitation, PM2.5 (µg/m3), current smoker, and other selected variables. Positive county-level β coefficient estimates ( P < .05) for atmospheric pressure were observed throughout the United States, higher in the eastern half of the country. Conclusion: The spatial regression models showed that atmospheric pressure is positively associated with age-adjusted lung cancer mortality rates, after controlling for other selected variables.

scholarly journals Lung Cancer Mortality Among Smokers and Never-Smokers in the United States

Epidemiology ◽  
2020 ◽  
Vol 31 (3) ◽  
pp. e24-e25
Author(s):  
H. Dean Hosgood ◽  
Candace Cosgrove ◽  
Madelyn Klugman ◽  
Thomas Rohan ◽  
Sean Altekruse
Keyword(s):  
United States ◽  
Lung Cancer ◽  
Cancer Mortality ◽  
Lung Cancer Mortality ◽  
The United States ◽  
Never Smokers

scholarly journals Residential Segregation and Lung Cancer Mortality in the United States

JAMA Surgery ◽  
2013 ◽  
Vol 148 (1) ◽  
pp. 37 ◽  
Author(s):  
Awori J. Hayanga ◽  
Steve B. Zeliadt ◽  
Leah M. Backhus
Keyword(s):  
United States ◽  
Lung Cancer ◽  
Residential Segregation ◽  
Cancer Mortality ◽  
Lung Cancer Mortality ◽  
The United States

scholarly journals Impact of Reduced Tobacco Smoking on Lung Cancer Mortality in the United States During 1975–2000

2012 ◽  
Vol 104 (7) ◽  
pp. 541-548 ◽  
Author(s):  
Suresh H. Moolgavkar ◽  
Theodore R. Holford ◽  
David T. Levy ◽  
Chung Yin Kong ◽  
Millenia Foy ◽  
...  
Keyword(s):  
United States ◽  
Lung Cancer ◽  
Tobacco Smoking ◽  
Cancer Mortality ◽  
Lung Cancer Mortality ◽  
The United States

scholarly journals State Variation in Low-Dose Computed Tomography Scanning for Lung Cancer Screening in the United States

2020 ◽  
Author(s):  
Stacey A Fedewa ◽  
Ella A Kazerooni ◽  
Jamie L Studts ◽  
Robert A Smith ◽  
Priti Bandi ◽  
...  
Keyword(s):  
United States ◽  
Computed Tomography ◽  
Lung Cancer ◽  
Cancer Screening ◽  
Cancer Mortality ◽  
Low Dose ◽  
Lung Cancer Screening ◽  
Lung Cancer Mortality ◽  
The United States ◽  
Cancer Burden

Abstract Background Annual lung cancer screening (LCS) with low-dose chest computed tomography in older current and former smokers (ie, eligible adults) has been recommended since 2013. Uptake has been slow and variable across the United States. We estimated the LCS rate and growth at the national and state level between 2016 and 2018. Methods The American College of Radiology’s Lung Cancer Screening Registry was used to capture screening events. Population-based surveys, the US Census, and cancer registry data were used to estimate the number of eligible adults and lung cancer mortality (ie, burden). Lung cancer screening rates (SRs) in eligible adults and screening rate ratios with 95% confidence intervals (CI) were used to measure changes by state and year. Results Nationally, the SR was steady between 2016 (3.3%, 95% CI = 3.3% to 3.7%) and 2017 (3.4%, 95% CI = 3.4% to 3.9%), increasing to 5.0% (95% CI = 5.0% to 5.7%) in 2018 (2018 vs 2016 SR ratio = 1.52, 95% CI = 1.51 to 1.62). In 2018, several southern states with a high lung-cancer burden (eg, Mississippi, West Virginia, and Arkansas) had relatively low SRs (&lt;4%) among eligible adults, whereas several northeastern states with lower lung cancer burden (eg, Massachusetts, Vermont, and New Hampshire) had the highest SRs (12.8%-15.2%). The exception was Kentucky, which had the nation’s highest lung cancer mortality rate and one of the highest SRs (13.7%). Conclusions Fewer than 1 in 20 eligible adults received LCS nationally, and uptake varied widely across states. LCS rates were not aligned with lung cancer burden across states, except for Kentucky, which has supported comprehensive efforts to implement LCS.

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