Clostridium perfringens enterotoxin carboxy-terminal fragment is a novel tumor-homing peptide for human ovarian cancer

Terminal Fragment ◽

Tumor Homing ◽

Homing Peptide ◽

Carboxy Terminal

Claudin-4 Overexpression in Epithelial Ovarian Cancer Is Associated with Hypomethylation and Is a Potential Target for Modulation of Tight Junction Barrier Function Using a C-Terminal Fragment of Clostridium perfringens Enterotoxin

Neoplasia ◽

10.1593/neo.07118 ◽

2007 ◽

Vol 9 (4) ◽

pp. 304-314 ◽

Cited By ~ 70

Author(s):

Babak Litkouhi ◽

Joseph Kwong ◽

Chun-Min Lot ◽

James G. Smedley ◽

Bruce A. McClane ◽

...

Keyword(s):

Ovarian Cancer ◽

Tight Junction ◽

Epithelial Ovarian Cancer ◽

Clostridium Perfringens ◽

Barrier Function ◽

Potential Target ◽

Terminal Fragment

Abstract 732: Iron oxide nanoparticles functionalized with the Clostridium Perfringens Enterotoxin carboxi-terminal fragment peptide: A novel diagnostic and therapeutic approach to specifically target ovarian cancer.

10.1158/1538-7445.am2013-732 ◽

2013 ◽

Author(s):

Emiliano Cocco ◽

Ileana Bortolomai ◽

Stefania Bellone ◽

Sara Gasparrini ◽

Diana English ◽

...

Keyword(s):

Ovarian Cancer ◽

Iron Oxide ◽

Iron Oxide Nanoparticles ◽

Clostridium Perfringens ◽

Therapeutic Approach ◽

Oxide Nanoparticles ◽

Terminal Fragment

Eradication of chemotherapy-resistant CD44+ human ovarian cancer stem cells in mice by intraperitoneal administration of clostridium perfringens enterotoxin

Cancer ◽

10.1002/cncr.26215 ◽

2011 ◽

Vol 117 (24) ◽

pp. 5519-5528 ◽

Cited By ~ 43

Author(s):

Francesca Casagrande ◽

Emiliano Cocco ◽

Stefania Bellone ◽

Christine E. Richter ◽

Marta Bellone ◽

...

Keyword(s):

Ovarian Cancer ◽

Stem Cells ◽

Cancer Stem Cells ◽

Clostridium Perfringens ◽

Human Ovarian Cancer ◽

Treatment of Chemotherapy-Resistant Human Ovarian Cancer Xenografts in C.B-17/SCID Mice by Intraperitoneal Administration of Clostridium perfringens Enterotoxin

Cancer Research ◽

10.1158/0008-5472.can-04-3472 ◽

2005 ◽

Vol 65 (10) ◽

pp. 4334-4342 ◽

Cited By ~ 76

Author(s):

Alessandro D. Santin ◽

Stefania Cané ◽

Stefania Bellone ◽

Michela Palmieri ◽

Eric R. Siegel ◽

...

Keyword(s):

Ovarian Cancer ◽

Clostridium Perfringens ◽

Scid Mice ◽

Human Ovarian Cancer ◽

Abstract 4369: Eradication of chemotherapy-resistant CD44+ human ovarian cancer stem cells in C.B-17/SCID mice by intraperitoneal administration of Clostridium Perfringens Enterotoxin (CPE)

10.1158/1538-7445.am2011-4369 ◽

2011 ◽

Author(s):

Alessandro D. Santin ◽

Emiliano Cocco ◽

Stefania Bellone ◽

Francesca Casagrande ◽

Marta Bellone ◽

...

Keyword(s):

Ovarian Cancer ◽

Stem Cells ◽

Cancer Stem Cells ◽

Clostridium Perfringens ◽

Scid Mice ◽

Human Ovarian Cancer ◽

The effect of intraperitoneal administration of clostridium perfringens enterotoxin on chemotherapy-resistant CD44+ human ovarian cancer stem cells in mice.

Journal of Clinical Oncology ◽

10.1200/jco.2011.29.15_suppl.e13077 ◽

2011 ◽

Vol 29 (15_suppl) ◽

pp. e13077-e13077

Author(s):

J. Varughese ◽

F. Casagrande ◽

E. Cocco ◽

S. Bellone ◽

C. E. Richter ◽

...

Keyword(s):

Ovarian Cancer ◽

Stem Cells ◽

Cancer Stem Cells ◽

Clostridium Perfringens ◽

Human Ovarian Cancer ◽

Abstract 364: In vivo targeting of CD44+ ovarian cancer stem cells (CSC) by Clostridium Perfringens Enterotoxin binding domain (CPE-peptide) conjugated to poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NP)

10.1158/1538-7445.am2012-364 ◽

2012 ◽

Cited By ~ 1

Author(s):

Emiliano Cocco ◽

Stefania Bellone ◽

Dana Roque ◽

Federica Guzzo ◽

Sara Gasparrini ◽

...

Keyword(s):

Ovarian Cancer ◽

Stem Cells ◽

Cancer Stem Cells ◽

Clostridium Perfringens ◽

Glycolic Acid ◽

Plga Nanoparticles ◽

Binding Domain ◽

Computational evaluation of a fusion protein consisted of pertussis toxin and filamentous hemagglutinin from Bordetella pertussis to target Claudin-4 using C-terminal fragment of Clostridium perfringens enterotoxin

Journal of Biomolecular Structure and Dynamics ◽

10.1080/07391102.2020.1794966 ◽

2020 ◽

pp. 1-10

Author(s):

Negar Souod ◽

Elham Rismani ◽

Fariborz Bahrami ◽

Saeed Reza Pakzad ◽

Soheila Ajdary

Keyword(s):

Fusion Protein ◽

Clostridium Perfringens ◽

Pertussis Toxin ◽

Bordetella Pertussis ◽

Computational Evaluation ◽

Terminal Fragment ◽

Filamentous Hemagglutinin

The application of an alanine-substituted mutant of the C-terminal fragment of Clostridium perfringens enterotoxin as a mucosal vaccine in mice

Biomaterials ◽

10.1016/j.biomaterials.2011.09.048 ◽

2012 ◽

Vol 33 (1) ◽

pp. 317-324 ◽

Cited By ~ 10

Author(s):

Hidehiko Suzuki ◽

Masuo Kondoh ◽

Hideki Kakutani ◽

Seiji Yamane ◽

Hiroshi Uchida ◽

...

Keyword(s):

Clostridium Perfringens ◽

Mucosal Vaccine ◽

Terminal Fragment

Domain mapping of a claudin-4 modulator, the C-terminal region of C-terminal fragment of Clostridium perfringens enterotoxin, by site-directed mutagenesis

Biochemical Pharmacology ◽

10.1016/j.bcp.2007.12.016 ◽

2008 ◽

Vol 75 (8) ◽

pp. 1639-1648 ◽

Cited By ~ 51

Author(s):

Azusa Takahashi ◽

Eriko Komiya ◽

Hideki Kakutani ◽

Takeshi Yoshida ◽

Makiko Fujii ◽

...

Keyword(s):

Clostridium Perfringens ◽

Terminal Region ◽

Site Directed Mutagenesis ◽

Directed Mutagenesis ◽

Terminal Fragment ◽

Domain Mapping